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81.
Uetsuka Y Hosoda S Kasanuki H Aosaki M Murasaki K Ooki K Inoue M Akiyama E Kitada M 《Heart and vessels》2000,15(3):124-128
The thrombotest (TT) technique has been widely used in Japan for monitoring oral anticoagulant therapy (OAT). The therapeutic
range was originally recommended to be 10%–25%. However, the International Committee for Standardization in Hematology/International
Committee on Thrombosis and Hemostasis (ICSH/ICTH) recommended using the international normalized ratio of prothrombin time
(PT-INR) for monitoring OAT. It is necessary to use a universal standard measure for monitoring OAT in accordance with the
ICSH/ISTH recommendation. We simultaneously measured TT and PT in blood samples from 1 157 patients on long-term warfarin
therapy, and studied the correlation between TT and PT-INR. An excellent linear correlation was obtained between TT-INR and
PT-INR with the regression equation PT-INR = 1.0420 TT-INR − 0.0987 (r = 0.905, P < 0.001). We also examined the correlation between the incidence of thromboembolism in 170 patients receiving warfarin therapy
after prosthetic valve replacement; 50.5% received concomitant antiplatelet therapy. Thromboembolism occurred in 9 of 170
patients during a mean follow-up period of 2.44 years. The average TT values in patients with and without thromboembolism
were 26.4% (PT-INR: 1.53) and 21.1% (1.73), respectively (P < 0.01). The incidence of thromboembolism did not differ significantly between patients on warfarin alone (average TT: 22.2%)
and those on warfarin and antiplatelet agent (average TT: 20.9%). Our results suggest that the incidence of thromboembolism
is low in Japan despite a less intensive regimen having been adopted.
Received: June 22, 2000 / Accepted: October 4, 2000 相似文献
82.
O Nishida F Moriyasu T Nakamura N Ban K Miura M Sakai H Uchino T Miyake 《Gastroenterology》1986,90(4):1042-1046
Blood flow volume of the portal venous system of 3 patients with splenic artery aneurysm, an uncommon disease, was measured using an ultrasonic duplex system. A huge increase in splenic blood flow volume was found in each case. A large portasystemic shunt through which the portal blood flowed hepatofugally was present in 2 cases. We suspect the shunt is partially responsible for an increase in splenic blood flow volume, which would lead to the formation of splenic artery aneurysm together with portal hypertension. 相似文献
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Katsuyoshi Sakaguchi Sawako Uehara Takakazu Yagi Shouichi Miyawaki 《Orthodontic Waves》2012,71(3):79-84
PurposeIt is clinically believed that humans with a broad and rounded dental arch accompanied by a shallow curve of Spee have good masticatory function. However, the relationship between them has not been elucidated fully. The purpose of this study was to quantitatively examine the relationship between occlusal curvatures and bite force.Materials and methodsBite force was measured and analyzed in 20 young adults with healthy permanent dentition and normal stomatognathic function using a bite force recording system. Study models of the mandibular dental arch were scanned with CCD cameras, and X, Y and Z coordinates of the cusp tips of the molars were recorded. Their occlusal curvatures were analyzed using a three-dimensional measurement system.ResultsBite force showed significant positive correlations (0.52 < R < 0.57) with the radius of the anteroposterior occlusal arc of the molar region and the radii of the translateral occlusal arcs in the second premolar, first molar and second molar regions, and showed significant positive correlation (R = 0.71) with the radius of the occlusal sphere of the molar region.ConclusionsIt was suggested that occlusal curvatures is related with the magnitude of bite force, and that the three dimensional spherical analysis of occlusal curvatures is useful predictor of the masticatory function. 相似文献
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Haruto Uchino Toshitaka Nakamura Kiyohiro Houkin Jun-ichi Murata Hisatoshi Saito Satoshi Kuroda 《Acta neurochirurgica》2013,155(4):599-605
Background
Postoperative hyperperfusion may lead to severe neurological complications after superficial temporal artery to middle cerebral artery (STA-MCA) anastomosis. However, there are no reliable modalities to predict the occurrence of postoperative hyperperfusion during surgery. The purpose of this study is to evaluate whether a semiquantitative analysis of indocyanine green (ICG) videoangiography could be useful in predicting postoperative hyperperfusion after STA-MCA anastomosis.Methods
This study included seven patients who underwent STA-MCA anastomosis due to occlusive carotid artery diseases. During surgery, ICG videoangiography was performed before and after bypass procedures, and ICG intensity–time curves were semiquantitatively analyzed to evaluate hemodynamic changes by calculating maximum intensity, time to peak (TTP), and blood flow index (BFI).Results
Maximum intensity significantly increased from 252.6?±?132.5 to 351.7?±?151.9 after bypass (p?<?0.001). TTP was significantly shortened from 12.9?±?4.4 s to 9.8?±?3.7 s (p?<?0.001). Furthermore, BFI significantly increased from 33.9?±?28.1 to 74.6?±?88.4 (p?<?0.05). Postoperative hyperperfusion was observed in five of seven patients 1 day after surgery. The ratio of BFI before and after bypass procedures was significantly higher in patients with postoperative hyperperfusion than those without, 2.5?±?1.1 and 1.5?±?0.4, respectively (p?=?0.013).Conclusions
These findings suggest that semiquantitative analysis of ICG videoangiography is helpful in predicting occurrence of hyperperfusion after STA-MCA anastomosis in patients with occlusive carotid artery diseases. 相似文献88.
Atsushi Fukunaga Katsuyoshi Shimizu Takahito Yazaki Masato Ochiai 《Acta neurochirurgica》2013,155(9):1693-1697
Background
Microvascular decompression (MVD) for hemifacial spasm (HFS) has been popular, but it may take enough time to master this special operative technique and procedure. This may induce uneven distribution of the number of MVD operations in each institute, possibly resulting in an overall unsatisfactory quality of MVD surgeons. Nakanishi’s approach to MVD operations has the feature of using a, “supine, no retractor” technique, which would achieve various benefits for patients and medical professionals. We would like to recommend this approach for MVD surgeons on the basis of our follow-up outcomes.Methods
A questionnaire, which was based on the method of evaluation for the long-term results of post-MVD operation as recommended by the Japanese Society of MVD, was sent by mail to the 154 HFS patients who had received Nakanishi’s approach at our hospital.Results
Except for 42 patients who had changed their residences, 89 patients (79.5 % of 112) fully answered. The mean postoperative follow-up term was 13.0 years. The 76.4 % of the patients was estimated as excellent. Postoperative deafness was not present. The average value of satisfaction degree for the results of the MVD operation was 87.9 %.Conclusions
This study revealed that Nakanishi’s approach produced good results equivalent of other approaches for HFS patients. This approach is considered to have many advantages comparing to the other approaches. Therefore, we would like to recommend that Nakanishi’s approach would contribute to overall advancement of the level of MVD surgeons. 相似文献89.
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