全文获取类型
收费全文 | 2125篇 |
免费 | 170篇 |
国内免费 | 131篇 |
专业分类
耳鼻咽喉 | 19篇 |
儿科学 | 29篇 |
妇产科学 | 31篇 |
基础医学 | 303篇 |
口腔科学 | 54篇 |
临床医学 | 231篇 |
内科学 | 438篇 |
皮肤病学 | 15篇 |
神经病学 | 114篇 |
特种医学 | 35篇 |
外科学 | 274篇 |
综合类 | 199篇 |
预防医学 | 96篇 |
眼科学 | 49篇 |
药学 | 227篇 |
7篇 | |
中国医学 | 143篇 |
肿瘤学 | 162篇 |
出版年
2024年 | 7篇 |
2023年 | 31篇 |
2022年 | 95篇 |
2021年 | 94篇 |
2020年 | 65篇 |
2019年 | 65篇 |
2018年 | 67篇 |
2017年 | 74篇 |
2016年 | 59篇 |
2015年 | 85篇 |
2014年 | 99篇 |
2013年 | 89篇 |
2012年 | 164篇 |
2011年 | 169篇 |
2010年 | 91篇 |
2009年 | 78篇 |
2008年 | 120篇 |
2007年 | 106篇 |
2006年 | 96篇 |
2005年 | 97篇 |
2004年 | 82篇 |
2003年 | 76篇 |
2002年 | 68篇 |
2001年 | 38篇 |
2000年 | 58篇 |
1999年 | 31篇 |
1998年 | 23篇 |
1997年 | 30篇 |
1996年 | 25篇 |
1995年 | 24篇 |
1994年 | 18篇 |
1993年 | 12篇 |
1992年 | 30篇 |
1991年 | 26篇 |
1990年 | 26篇 |
1989年 | 24篇 |
1988年 | 21篇 |
1987年 | 13篇 |
1986年 | 8篇 |
1985年 | 3篇 |
1984年 | 9篇 |
1983年 | 10篇 |
1982年 | 3篇 |
1981年 | 2篇 |
1979年 | 5篇 |
1977年 | 2篇 |
1976年 | 1篇 |
1974年 | 1篇 |
1972年 | 4篇 |
1933年 | 1篇 |
排序方式: 共有2426条查询结果,搜索用时 15 毫秒
31.
32.
Jie Zhou Bangmin Zhou Xiaoyue Kou Tao Jian Limei Chen Xinghua Lei Shijian Jia Xiaoying Xie Xianbo Wu 《Medicine》2023,102(9)
Acupoint application has served as an important complementary and adjunctive therapy in China. The purpose of this study is to explore the impact of summer acupoint application treatment (SAAT) on the abundance and biological structure of gut microbiota in healthy Asian adults. Based on the CONSORT guidelines, 72 healthy adults were included in this study, randomly divided into 2 groups, receiving either traditional (acupoint application within known relevant meridians, Group A) or sham (treated with placebo prepared by mixing the equal amount of starch and water, Group B) SAAT. SAAT stickers include extracts from Rhizoma Corydalis, Sinapis alba, Euphorbia kansui, Asari Herba, and the treatment group received 3 sessions of SAAT for 24 months, administered to BL13 (Feishu), BL17 (Geshu), BL20 (Pishu), and BL23 (Shenshu) acupoints. Fecal microbial analyses via ribosomal ribonucleic acid (rRNA) sequencing were performed on donor stool samples before and after 2 years of SAAT or placebo treatment to analyze the abundances, diversity, and structure of gut microbiota. No significant baseline differences were present between groups. At the phylum level, the baseline relative abundance of Firmicutes, Bacteroidetes, Proteobacteria, Actinobacteria, and Fusobacteria was identified in fecal samples collected from each group. After treatment, the relative abundance of Firmicutes was significantly increased in both groups (P < .05). Notably, a significant decrease in the relative abundance of Fusobacteria was observed in the SAAT treatment group (P < .001), while the abundance of Bacteroidetes was decreased significantly in the placebo group (P < .05). At the genus level, the relative abundance of Faecalibacterium and Subdoligranulum species in the 2 groups were all significantly increased (P < .05). In addition, a significant reduction in the relative abundance of Blautia, Bacteroides, and Dorea in Group A (P < .05) and Eubacterium hallii group and Anaerostipes (P < .05) in Group B was observed after treatment. Our findings indicated SAAT substantially influenced the bacterial community structure in the gut microbiota of healthy Asian adults, which might serve as potential therapeutic targets for related diseases, and provided a foundation for future studies aimed at elucidating the microbial mechanisms underlying SAAT for the treatment of various conditions such as obesity, insulin resistance, irritable bowel syndrome. 相似文献
33.
The crystallization and viscosity of modified blast furnace slag are key factors in fiber forming conditions. In this paper, the crystallization behavior of modified blast furnace slag under continuous cooling conditions was studied by differential scanning calorimetry, and its crystallization kinetics with different acidity coefficients were established. On this basis, the evolution law of the crystallization phase and the influence of crystallization on the viscosity of modified blast furnace slag with different acidity coefficients were analyzed. The results indicated that the crystallization phases of slag with acidity coefficients of 1.05 and 1.20 were, respectively, Melilite and Anorthite. During the cooling process at the acidity coefficient of 1.05, the critical rates of precipitation of Melilite and Anorthite were 50 °C/s and 20 °C/s, respectively, while they were 20 °C/s and 15 °C/s, respectively, at the acidity coefficient of 1.20. With the increase of the acidity coefficient, the crystal growth mode of slag changed from two-dimensional and three-dimensional mixed crystallization to surface nucleation and one-dimensional crystallization. The crystallization activation energy of slag with acidity coefficients of 1.05 and 1.20 were 698.14 kJ/mol and 1292.50 kJ/mol, respectively. In addition, the change trend of viscosity was related to crystal size and content. 相似文献
34.
Yang Bai Liang Wen Yulong Zhao Jianan Li Chen Guo Xiaobin Zhang Jiaming Yang Yushu Dong Litian Ma Guobiao Liang Yun Kou Enxin Wang 《Medicine》2022,101(18)
Information about coronavirus disease 2019 (COVID-19) patients with pre-existing chronic obstructive pulmonary disease (COPD) is still lacking. The aim of this study is to describe the clinical course and the outcome of COVID-19 patients with comorbid COPD.This retrospective study was performed at Wuhan Huoshenshan Hospital in China. Patients with a clear diagnosis of COVID-19 who had comorbid COPD (N = 78) were identified. COVID-19 patients without COPD were randomly selected and matched by age and sex to those with COPD. Clinical data were analyzed and compared between the two groups. The composite outcome was the onset of intensive care unit admission, use of mechanical ventilation, or death during hospitalization. Multivariable Cox regression analyses controlling for comorbidities were performed to explore the relationship between comorbid COPD and clinical outcome of COVID-19.Compared to age- and sex-matched COVID-19 patients without pre-existing COPD, patients with pre-existing COPD were more likely to present with dyspnea, necessitate expectorants, sedatives, and mechanical ventilation, suggesting the existence of acute exacerbations of COPD (AECOPD). Greater proportions of patients with COPD developed respiratory failure and yielded poor clinical outcomes. However, laboratory tests did not show severer infection, over-activated inflammatory responses, and multi-organ injury in patients with COPD. Kaplan–Meier analyses showed patients with COPD exhibited longer viral clearance time in the respiratory tract. Multifactor regression analysis showed COPD was independently correlated with poor clinical outcomes.COVID-19 patients with pre-existing COPD are more vulnerable to AECOPD and subsequent respiratory failure, which is the main culprit for unfavorable clinical outcomes. However, COPD pathophysiology itself is not associated with over-activated inflammation status seen in severe COVID-19. 相似文献
35.
肠造口病人生活质量的研究进展 总被引:9,自引:0,他引:9
介绍了肠造口病人生活质量状况的研究进展。从影响肠造口病人生活质量的相关因素及所采取的措施进行了综述。 相似文献
36.
Fan Kou Lei Wu Yan Guo Bailu Zhang Baihui Li Ziqi Huang Xiubao Ren Lili Yang 《癌症生物学与医学(英文版)》2022,19(5):685-695
Objective: Lung cancer is the most common cause of cancer-related deaths worldwide. Somatic copy number alterations(SCNAs) have been used to predict responses to therapies in many cancers, including lung cancer. However, little is known about whether they are predictive of radiotherapy outcomes. We aimed to understand the prognostic value and biological functions of SCNAs.Methods: We analyzed the correlation between SCNAs and clinical outcomes in The Cancer Genome Atlas data for 486 patients wit... 相似文献
37.
38.
39.
40.
Maneesha Bhaya M.D. Ferit Onur Mutluer M.D. Edward Mahan M.D. Luke Mahan Ming C. Hsiung M.D. Wei–Hsian Yin M.D. Ph.D. Jeng Wei M.D. MsD Shen–Kou Tsai M.D. Ph.D. Guang–Yu Zhao M.D. Wei–Hsian Yin M.D. Manish Pradhan M.D. Rajesh Beniwal M.D. Deepak Joshi M.D. Fatemeh Nabavizadeh M.D. Amitoj Singh M.B.B.S. Navin C. Nanda M.D. 《Echocardiography (Mount Kisco, N.Y.)》2013,30(3):345-353