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31.
目的探讨腹腔镜经腹腹膜前疝修补术(TAPP)放置腹膜前引流对术后血肿及血清肿的影响。
方法选取2016年6月至2018年5月,江苏省苏州市中西医结合医院收治的单侧腹股沟疝患者90例,随机分为试验组和对照组,2组患者均行TAPP手术。试验组放置腹膜前引流管,对照组不放置引流管。收集2组患者的一般资料、手术相关资料及随访资料进行统计学分析,对比2组患者术后血肿及血清肿发生率差异。
结果全部患者均完成手术及随访。2组患者的一般资料、疝位置、疝分型、手术时间、住院花费、术后住院时间差异无统计学意义(P>0.05)。2组患者的术后发热发生率、急性疼痛发生率差异无统计学意义(P>0.05)。试验组术后血肿发生率明显低于对照组(P<0.05),试验组患者术后1和3个月血清肿发生率明显低于对照组,差异有统计学意义(P<0.05)。2组患者1年随访均观察到1例复发的病例,差异无统计学意义(P>0.05);随访期内2组患者均未出现感染的病例。
结论TAPP中,放置腹膜前引流管能够有效降低患者术后血肿和血清肿的发生率,同时并不增加感染和复发风险。 相似文献
32.
癫痫作为多种病因引起的神经系统慢性、发作性疾病,严重影响着患者的生活质量,因此对其及时诊断和早期治疗极为重要。目前已有多种神经影像技术用于癫痫的定位、定侧和病理生理研究。弥散张量成像是利用水分子在组织中弥散的各向异性成像的磁共振技术,是目前唯一能在活体中无创性地显示脑白质纤维束的方法,它能敏感地显示脑部细微结构,并能揭示各个结构间的功能联系,有助于癫痫的研究。本文主要从癫痫的病因诊断、癫痫手术的辅助指导、癫痫的结构网络及其与癫病功能障碍的相关性研究等方面对DTI应用于癫痫的最新研究进展进行综述。 相似文献
33.
Amosova E. N. Shilova I. V. Zueva E. P. Rybalkina O. Yu. 《Pharmaceutical Chemistry Journal》2020,54(7):721-724
Pharmaceutical Chemistry Journal - Three extracts were produced from the above-ground part of the meadowsweet Filipendula ulmaria (L.) Maxim. using water, 40% ethanol, and 70% ethanol. Comparative... 相似文献
34.
Xin Yi Wong Andrew Qi Jun Lim Qianyu Shen John Whay Kuang Chia Min Hoe Chew Wah Siew Tan 《Current medical research and opinion》2020,36(10):1677-1686
Abstract
Objective
Ras wild-type metastatic colorectal cancers (mCRC) may be treated with anti-vascular endothelial growth factor (VEGF) or anti-epidermal growth factor receptor (EGFR) agents. We aim to estimate patients’ preferences for mCRC treatment and relative importance of cost, efficacy improvement, avoidance of side effects and therapy convenience, and relative uptake between profiles that resemble Bevacizumab (anti-VEGF) and Cetuximab (anti-EGFR), two commonly prescribed mCRC targeted therapies. 相似文献35.
Yaqian Li Jingjing Yu Yun Kuang Chengkun Wu Liu Yang Qiulian Fang 《Current medical research and opinion》2020,36(9):1433-1439
Abstract
Objective
The sex, age, medical history, treatment, tobacco use, race risk (SAMe-TT2R2) Score; the sex, age, medical history, treatment, tobacco use, genotype combination (SAMe-TT2G2) Score; and the so-called modified SAMe-TT2R2 scores have been proposed to predict the anticoagulation quality for patients with non-valvular atrial fibrillation (NVAF). The data from a prospective controlled study is used to validate the SAMe-TT2R2 and SAMe-TT2G2 scores in Chinese NVAF patients treated with warfarin and to evaluate the association of factors with time in therapeutic range (TTR) to predict the quality of oral anticoagulation control. 相似文献36.
37.
Peng Li Sha-Sha Tao Meng-Qin Zhao Jun Li Xiu Wang Hai-Feng Pan 《Immunological investigations》2015,44(7):603-615
Objective: Association of matrix metalloproteinases (MMPs) gene polymorphisms with rheumatoid arthritis is controversial. We conduct a meta-analysis to clarify this dispute.Methods: We systematically searched the electronic PUBMED, EMBASE and CNKI databases for research articles about MMPs (MMP-1, MMP-2, MMP-3, MMP-9) gene polymorphisms and rheumatoid arthritis (RA) up to January 2015. According to the heterogeneity, fixed-effects or random-effects models were used to calculate crude odds ratios (ORs) and 95% confidence intervals (95% CIs).Results: A total of 11 articles involving 2143 cases and 2049 controls were included in this meta-analysis. Overall, no significant associations were observed between MMP-1-1607 1G/2G polymorphism and RA. Stratification by ethnicity, no significant associations were observed in Caucasian populations. Similarly, no significant associations were observed between MMP-3-1171 5A/6A, MMP-9-1562 C/T polymorphisms and RA in overall and Caucasian populations, respectively. However, a weak association was found between MMP-2-1306 C/T polymorphism and RA (C vs. T, OR?=?0.813, 95%CI?=?0.694–0.953, p?=?0.010) in overall populations.Conclusions: The present meta-analysis suggests that MMP-1-1607 1G/2G, MMP-3-1171 5A/6A, MMP-9-1562 C/T polymorphisms are not associated with the susceptibility of RA, but MMP-2 -1306 C/T is weakly associated with susceptibility to RA. Further studies with more sample size are needed for definitive conclusions. 相似文献
38.
European Archives of Oto-Rhino-Laryngology - Several polymorphisms in a disintegrin and metalloproteinase 33 (ADAM33) have been implicated in susceptibility to allergic rhinitis (AR), but the... 相似文献
39.
Dan-Feng Xu Bing Wu Jin-Xin Wang Jian Yu Jian-Xin Xie 《World Journal of Clinical Cases》2021,9(5):1096-1102
BACKGROUNDGuillain-Barré syndrome (GBS) is a rare disorder that typically presents with ascending weakness, pain, paraesthesias, and numbness, which mimic the findings in lumbar spinal stenosis. Here, we report a case of severe lumbar spinal stenosis combined with GBS.CASE SUMMARYA 70-year-old man with a history of lumbar spinal stenosis presented to our emergency department with severe lower back pain and lower extremity numbness. Magnetic resonance imaging confirmed the diagnosis of severe lumbar spinal stenosis. However, his symptoms did not improve postoperatively and he developed dysphagia and upper extremity numbness. An electromyogram was performed. Based on his symptoms, physical examination, and electromyogram, he was diagnosed with GBS. After 5 d of intravenous immunoglobulin (0.4 g/kg/d for 5 d) therapy, he gained 4/5 of strength in his upper and lower extremities and denied paraesthesias. He had regained 5/5 of strength in his extremities when he was discharged and had no symptoms during follow-up.CONCLUSIONGBS should be considered in the differential diagnosis of spinal disorder, even though magnetic resonance imaging shows severe lumbar spinal stenosis. This case highlights the importance of a careful diagnosis when a patient has a history of a disease and comes to the hospital with the same or similar symptoms. 相似文献
40.
目的 总结国产封堵器经皮和经胸途径治疗先天性心脏病的临床疗效。方法 回顾性分析我院2013年1月至2017年12月在X线透视下或单纯超声心动图引导下采用经皮穿刺股静脉或股动静脉法,或者食管超声心动图监测下经胸小切口行先天性心脏病封堵1186例,其中经皮X线下封堵1081例、经皮单纯超声引导下封堵42例、经胸封堵63例;其中动脉导管未闭( patent ductus arteriole,PDA)426例、房间隔缺损(atrial septal defect,ASD)363例、室间隔缺损(ventricular septal defect,VSD)348例、卵圆孔未闭11例、房间隔缺损合并室间隔缺损9例、房间隔缺损合并动脉导管未闭6例、房间隔缺损合并肺动脉瓣狭窄(pulmonary stenosis,PS)12例、动脉导管未闭合并肺动脉瓣狭窄8例、主肺动脉侧支封堵3例[经胸封堵66例改为63例,PDA443例改为426例]。结果 全组病例成功率98.2%(1165/1186),无死亡病例。随访1~36个月,术后第1、3、6、12个月及术后每年常规行超声心动图及心电图检查。术后第1、6、12个月的随访率分别为 92.9%(1102/1186)、84.1%(998/1186)、70.5%(836/1186)。超声心动图提示少量残余分流(<3 mm)18例;三尖瓣少量反流33例,中量反流5例;主动脉瓣轻度反流5例,中度反流1例;心律失常Ⅲ°房室传导阻滞(Avionics Bulletin,AVB[房室传导阻滞(Avionics Bulletin,AVB)])1 例,Ⅱ°AVB 3例,完全性左束支3例,交界性心动过速3例,交界性逸搏2例。结论 国产封堵器在先天性心脏病封堵治疗中具有成功率高、创伤小、并发症低、操作容易、疗效确切、恢复快等特点,是治疗先天性心脏病的理想方法。 相似文献