慢性砷中毒自觉症状和皮肤改变影响因素的Logistic分析

目的探讨慢性砷中毒患者自觉症状、皮肤色素异常丑过度角化的影响因素。方法选择山西大同地区山阴县黑疙瘩乡大营村进行调查问卷及体检,结果进行单因素及多因素Logistic逐步回归分析。结果单因素分析提示,年龄、迁入时间、饮含砷井水时间、吸烟、饮茶等与自觉症状、色素异常及皮肤角化显著相关,水果是保护因素。多因素Logistic逐步回归分析结果表明,年龄、迁入时间是自觉症状的主要危险因素;年龄是色素异常的主要危险因素,水果摄入是保护因素;年龄、迁入时间、饮含砷井水时间是皮肤过度角化的主要危险因素,水果摄入是保护因素。结论自觉症状及皮肤改变主要与砷的撮入及蓄积量有关。砷中毒病区地理环境背景也是影响皮肤改变的因素之一。水果等抗氧化物质的摄入可能起保护作用。     

日本血吸虫与HBV合并感染对幽门螺杆菌感染的影响

目的 :探讨HBV与日本血吸虫合并感染对幽门螺杆菌 (Hp)感染的影响。 方法 :利用Hp全菌抗原检测HBV、日本血吸虫单独或合并感染者血清抗HpIgG抗体。 结果 :HBV与血吸虫合并感染时 ,血清HpIgG抗体检出率 ( 85.7% )明显高于HBV或血吸虫单独感染 (阳性率分别为 4 5.5%和 72 .9% ) ,合并感染时血清抗体水平 ( 0 .87± 0 .1 0 )亦高于单独感染 ( 0 .77± 0 .2 0 ,0 .70± 0 .1 7) ,差异有显著性意义。HBV阳性者与HBV阴性者之间Hp 感染率和抗体水平相近。结论 :HBV和血吸虫合并感染对Hp感染具有协同作用     

脑梗塞患者脂蛋白(A)水平与肾脏早期损害

为探讨脑梗塞患者脂蛋白（Ａ）水平与肾脏早期损害的关系,应用ＥＬＩＳＡ法及化学显色终点法分别检测４０例梗塞患者血清ＬＰ（Ａ）水平和尿氨基葡萄糖苷酶活力。结果表明,脑梗塞组血ＬＰ（Ａ）及ＮＡＧ均明显高于正常对照组,且ＬＰ（Ａ）值与尿ＮＡＧ活力呈正相关。     

430名新疆哈萨克族成人同身寸长度与身高关系的研究

目的：研究新疆哈萨克族成人同身寸长度与身高的关系,为人类学、法医学研究以及针灸取穴提供基础资料。方法：应用 Ｈｒｄｌｉｃｋａ 标准和我国普遍采用的方法测量了４３０ 名（男１９７ 名,女２３３ 名）新疆哈萨克族成人同身寸长和身高。结果：按性别和年龄分组,计算出各组同身寸的均值、身高的均值及身高与同身寸的比值,并提出了由同身寸推算身高的回归方程。结论：通过同身寸长可推算身高,同身寸长和身高有显著性的直结回归关系。     

血塞通、爱维治、胰岛素治疗急性脑梗死34例临床观察

目的：观察血塞通、爱维治、胰岛素对脑梗死的综合治疗作用。方法：选择34例病人为治疗组,随机抽取37例应用低右加复方丹参注射液加维脑路通治疗的病人为对照组,通过比较观察确定治疗效果。结果：治疗组显效率为79．4％,总有效率为94.1％。经统计表明,两组病人治疗显效率有显著性差异（P＜0．05）。结论：该疗法效果明显且无任何毒副作用,具有较高的临床应用价值。     

利培酮与氯氮平治疗首发精神分裂症的对照研究

目的：比较利培酮和氯氮平治疗首发精神分裂症的有效性和安全性。方法：６０例ＢＰＲＳ总分≥４０分,符合ＣＣＭＤ－２－Ｒ精神分裂症诊断标准的患者,随机分为两组进行对照研究,分别给予利培酮和氯氮平口服治疗,以ＢＰＲＳ减分率为疗效评定指标,以ＴＥＳＳ评价副反应指标。结果：利培酮治疗首发精神分裂症疗效肯定,８周末有效率为９０％,与氯氮平相仿。利培酮在治疗１周后起效,焦虑、抑郁和迟滞等症状群起效更早,明显早于氯氮平。剂量较小者锥体外系副反应轻,其它不良副反应发生率和严重程度均较氯氮平少而轻。结论：利培酮是治疗精神分裂症有效、安全的一线抗精神病药物     

CT 对腮腺区肿块的诊断价值

评价ＣＴ对腮腺肿瘤的诊断价值。方法８８例腮腺区肿瘤进行ＣＴ平扫,ＣＴ增强扫描和／或腮腺造影ＣＴ扫描。结果：７８例为腺内肿瘤,其中７例为恶性;１０例为腺肿瘤。对ＣＴ肋腺区肿瘤定位准确,能准确显示肿瘤的范围,大小,数目及浸润情况。     

Duration and recovery profile of cisatracurium after succinylcholine during propofol or isoflurane anesthesia

Study Objective: To determine the duration and recovery profile of maintenance doses of cisatracurium besylate following succinylcholine, and during propofol or isoflurane anesthesia.

Design: Randomized, open-label study.

Setting: Operating suite of a university-affiliated medical center.

Patients: Forty ASA physical status I and II adult patients having elective surgery with general anesthesia lasting longer than 90 minutes.

Interventions: Following a standardized induction sequence, a baseline electromyogram (EMG) was obtained. An intubating dose of intravenous (IV) succinylcholine 1.0 mg/kg was administered. Ventilation was maintained with a face mask until the first twitch (T₁) of the evoked train-of-four (TOF) reached 10% of control when tracheal intubation was performed. Spontaneous recovery from neuromuscular blockade was allowed to occur until the first twitch returned to 25% of control. Patients then were randomized to receive cisatracurium as follows. Group 1: 0.025 mg/kg [0.5 × 95% effective dose (ED₉₅)]; Group 2: 0.05 mg/kg (ED₉₅); Group 3: 0.05 mg/kg (ED₉₅); and Group 4: 0.1 mg/kg (2×ED₉₅). Anesthesia for Groups 1 and 2 were maintained with isoflurane 1% to 2%, 66% nitrous oxide (N₂O) in oxygen (O₂), and in Groups 3 and 4, anesthesia was maintained with propofol 80 to 160 μg/kg/min, 66% N₂O in O₂. The TOF-evoked EMG was recorded at 10-second intervals. The time for the evoked EMG to spontaneously return to 25%, 50%, and 75% of the original baseline was recorded.

Measurements and Main Results: There were 10 patients in each of the four groups. The duration of action of cisatracurium 0.05 mg/kg (ED₉₅) after an intubating dose of succinylcholine is 24.5 ± 10 minutes and 21.3 ± 9 minutes during anesthesia maintained with isoflurane and propofol, respectively. Doubling the dose of cisatracurium resulted in approximately twice the duration of action (40.2 ± 7 min) during propofol anesthesia. Following a dose of cisatracurium 0.025 mg/kg (0.5×ED₉₅), the T₁ of the EMG-evoked response did not decrease below 25% in 7 of 10 patients.

Conclusion: Following succinylcholine, the duration of action of a single dose of cisatracurium 0.05 mg/kg is 20 to 25 minutes during anesthesia maintained with propofol or isoflurane. The duration and recovery profile of cisatracurium is dose dependent during propofol and isoflurane anesthetics. Cisatracurium 0.025 mg/kg is an inadequate maintenance dose following recovery from succinylcholine and it fails to provide adequate surgical relaxation.     

晚期肺癌73例外科治疗分析

目的 总结近９ａ实施的肺癌手术２０３例,其中属于Ⅲｂ或Ⅳ期的晚期肺癌７３例,旨在讨论晚期肺癌的手术指征,手术操作要点。方法 行全肺切除１８例（左肺１５例,右肺３例）,肺叶切除５４例,肺癌切除后复发余肺切除１例,经心包内处理肺血管１７例,合并民房部分切除２例;支气管成形术１３敢管隆凸成形术１例。结果 除１例因急性呼吸功能衰竭导致死亡外,其余均临床治愈,术后生存率１ａ内为９５％,１ａ以不足２ａ为８０％     

薄层扫描法测定金龙祛痹丸中士的宁的含量

目的：马钱子粉系金龙祛痹丸中具毒怀的中药,为确保本品的安全有效,须建立其含量测定方法。方法：采用薄层扫描法测定金龙祛痹丸中士的宁的含量。以甲苯－丙酮－乙醇－浓氨试液为展开剂;单波长反射法锯齿扫描,测定波长为２５４ｎｍ。结果：通过方法学考察,点样量在０．５３５－３．２１０μｇ范围内线性关系良好,平均回收率为９９．１％。结论：试验表明,方法可靠,数据准确,操作简便、 行。