全文获取类型
收费全文 | 9411篇 |
免费 | 603篇 |
国内免费 | 188篇 |
专业分类
耳鼻咽喉 | 204篇 |
儿科学 | 64篇 |
妇产科学 | 48篇 |
基础医学 | 1777篇 |
口腔科学 | 167篇 |
临床医学 | 892篇 |
内科学 | 2269篇 |
皮肤病学 | 348篇 |
神经病学 | 715篇 |
特种医学 | 417篇 |
外科学 | 980篇 |
综合类 | 65篇 |
现状与发展 | 1篇 |
预防医学 | 385篇 |
眼科学 | 111篇 |
药学 | 945篇 |
中国医学 | 169篇 |
肿瘤学 | 645篇 |
出版年
2024年 | 4篇 |
2023年 | 57篇 |
2022年 | 303篇 |
2021年 | 509篇 |
2020年 | 214篇 |
2019年 | 274篇 |
2018年 | 321篇 |
2017年 | 231篇 |
2016年 | 360篇 |
2015年 | 457篇 |
2014年 | 571篇 |
2013年 | 612篇 |
2012年 | 1063篇 |
2011年 | 936篇 |
2010年 | 485篇 |
2009年 | 396篇 |
2008年 | 532篇 |
2007年 | 513篇 |
2006年 | 403篇 |
2005年 | 392篇 |
2004年 | 271篇 |
2003年 | 266篇 |
2002年 | 218篇 |
2001年 | 172篇 |
2000年 | 174篇 |
1999年 | 130篇 |
1998年 | 56篇 |
1997年 | 45篇 |
1996年 | 20篇 |
1995年 | 21篇 |
1994年 | 22篇 |
1993年 | 16篇 |
1992年 | 26篇 |
1991年 | 18篇 |
1990年 | 24篇 |
1989年 | 13篇 |
1988年 | 16篇 |
1987年 | 9篇 |
1986年 | 9篇 |
1985年 | 10篇 |
1984年 | 5篇 |
1983年 | 5篇 |
1982年 | 2篇 |
1981年 | 3篇 |
1979年 | 4篇 |
1976年 | 4篇 |
1973年 | 2篇 |
1958年 | 1篇 |
1940年 | 1篇 |
1939年 | 1篇 |
排序方式: 共有10000条查询结果,搜索用时 78 毫秒
951.
Sang-Pyo Lee Sang-Heon Kim Tae Hyung Kim Jang Won Sohn Dong Ho Shin Sung Soo Park Ho Joo Yoon 《Journal of Korean medical science》2010,25(1):148-151
An 82-yr-old man was presented with fever and cough accompanied by generalized erythematous rash. He had taken mexiletine for 5 months, as he had been diagnosed with dilated cardiomyopathy and ventricular arrhythmia. Laboratory studies showed peripheral blood eosinophilia and elevated liver transaminase levels. Chest radiographs showed multiple nodular consolidations in both lungs. Biopsies of the lung and skin lesions revealed eosinophilic infiltration. After a thorough review of his medication history, mexiletine was suspected as the etiologic agent. After discontinuing the mexiletine and starting oral prednisolone, the patient improved, and the skin and lung lesions disappeared. Subsequently, mexiletine was confirmed as the causative agent based on a positive patch test. Drug-induced hypersensitivity syndrome is a severe adverse reaction to drugs and results from treatment with anticonvulsants, allopurinol, sulfonamides, and many other drugs. Several cases of mexiletine-induced hypersensitivity syndrome have been reported in older Japanese males with manifestation of fever, rash, peripheral blood eosinophilia, liver dysfunction without other organ involvement. Here, we report a case of mexiletine-induced hypersensitivity syndrome which presented as eosinophilic pneumonia in a Korean male. 相似文献
952.
H J Jang H K Lim W J Lee S H Kim K A Kim E Y Kim 《Journal of ultrasound in medicine》2000,19(5):293-299
A prospective study was performed to evaluate whether pulse inversion harmonic imaging and tissue harmonic imaging improve the lesion conspicuity and change ultrasonographic characteristics of focal hepatic lesions. Three radiologists evaluated 97 focal hepatic lesions by consensus: cirrhosis‐related nodules (n = 23), metastases (n = 23), hemangiomas (n = 27), and cysts (n = 24). In our study, pulse inversion harmonic imaging was judged superior to both tissue harmonic imaging and conventional imaging in conspicuity and overall quality for cirrhosis‐related nodules, metastases, and cysts (P < 0.05). Compared with conventional imaging, both pulse inversion harmonic imaging and tissue harmonic imaging provided better conspicuity, clearer internal echogenicity, and stronger through‐transmission of cysts (P < 0.05). Pulse inversion harmonic imaging was judged to be better in depicting internal morphology for cirrhosis‐related nodules and metastases than conventional imaging (P < 0.05). For hemangiomas, no statistically significant difference was found in all parameters except better posterior enhancement by tissue harmonic imaging than other techniques. In conclusion, pulse inversion harmonic imaging showed the best conspicuity and also enhanced characteristics of both cystic and solid hepatic lesions. Tissue harmonic imaging was judged superior to conventional imaging in evaluating cysts but was not beneficial for solid lesions. The results of this trial may be specific to the machine used for this study. 相似文献
953.
Dae-Hyun Jang 《Developmental neurorehabilitation》2014,17(6):414-419
Objective: To identify factors associated with the efficacy of botulinum toxin-A (BoNT-A) injections. Methods: Thirty-eight children with spastic cerebral palsy (CP) received BoNT-A injections into the gastrocnemius. The baseline anti-botulinum antibodies were checked. The Static dorsiflexion range of motion (ROM), Modified Tardieu Scale (MTS) and Physician Rating Scale (PRS) were assessed at pre-injection as well as 4- and 12-week post-injection. Results: No samples contained anti-botulinum antibodies. Greater baseline MTS dynamic range was associated with greater changes in MTS dynamic ranges at 4-week post-injection. More frequent physical therapy was associated with greater changes in static dorsiflexion ROM at 4-week post-injection and greater changes in PRS at 4- and 12-week post-injection. Conclusion: The improvement in PRS at 12-week post-injection was associated with the frequency of physical therapy. Therefore, intensive physical therapy programs may be necessary to maintain the beneficial effects of BoNT-A injections in children with CP. 相似文献
954.
Keun Young Shin Jun Heo Ji Yeon Kim Sang Jik Lee Se Young Jang Soo Young Park Min Kyu Jung Chang Min Cho Won Young Tak Young Oh Kweon 《Clinical and molecular hepatology》2011,17(2):148-151
Radiofrequency ablation (RFA) is performed as an alternative to surgical resection for primary or secondary liver malignancies. Although RFA can be performed safely in most patients, early and late complications related to mechanical or thermal damage occur in 8-9.5% cases. Hemocholecyst, which refers to hemorrhage of the gallbladder, has been reported with primary gallbladder disease or as a secondary event associated with hemobilia. Hemobilia, defined as hemorrhage in the biliary tract and most commonly associated with accidental or iatrogenic trauma, is a rare complication of RFA. Here we report a case of hemocholecyst associated with hemobilia after RFA for hepatocellular carcinoma that was successfully managed by laparoscopic cholecystectomy. 相似文献
955.
956.
Min Soo Jang Jun Gyu Jang Sang Hwa Han Jong Bin Park Dong Young Kang Sang Tae Kim Kee Suck Suh 《The Journal of dermatology》2013,40(8):606-612
There are no reports on the clinicopathological features of mycosis fungoides (MF) among veterans exposed to Agent Orange, one of the herbicides used during the Vietnam War. To evaluate the clinical, histopathological and genotypic findings of Vietnam War veterans with MF and a positive history of exposure to Agent Orange, we performed a comparative clinicopathological study between MF patients with a history of Agent Orange exposure and those without a history of Agent Orange exposure. Twelve Vietnam War veterans with MF were identified. The mean interval from Agent Orange exposure to diagnosis was 24.5 years (range, 9–35). Skin lesions were significantly present on exposed and unexposed areas. Most patients (75%) experienced pruritus (mean visual analog scale score of 6.7). MF was manifested by plaques in 10 patients and by lichenification in five. Histopathological features of most cases were consistent with MF. Biopsy specimens also demonstrated irregular acanthosis (66.7%). In the comparative study, MF patients with a history of Agent Orange exposure differed significantly from those without exposure to Agent Orange in demographic and clinical characteristics. In addition, patients with exposure had an increased tendency for lesions in the exposed area. Notably, our patients showed a higher frequency (33.3%) of mycosis fungoides palmaris et plantaris than in previous studies. Histologically, irregular acanthosis was more frequently observed than ordinary MF. Our results indicate that dermatologists should pay close attention to these clinicopathological differences. Careful assessment of history of exposure to defoliants is warranted in some cases suspicious for MF. 相似文献
957.
Purpose: To evaluate the complications of high-intensity focused ultrasound (HIFU) in patients with hepatic and pancreatic cancer.
Materials and Methods: From January 2006 to December 2008, 133 sessions of HIFU treatment were performed in 114 consecutive patients with primary
hepatic tumor (n = 57), hepatic metastasis (n = 22), and pancreatic cancer (n = 35) under general anesthesia. The extracorporeal, ultrasound-guided Model-JC system (HAIFU, Chongqing, China) was used.
Artificial pleural effusion was created to obtain an adequate sonographic window for ablating hepatic dome masses in 53 patients.
We reviewed medical records and imaging findings before, during, and after HIFU. Results: All patients had skin redness, edema, and pain in the treatment regions. All hepatic tumor patients had necrosis of the
ribs along the main ultrasound beam path that did not require further treatment. Major complications included biliary obstruction,
symptomatic pleural effusion, pneumothorax and fistula formation between an abdominal wall abscess and the ablated hepatic
tumor. In 35 pancreatic cancer patients, major complications included third-degree burns and fistula formation between the
tumor and duodenum. Delayed complications in hepatic tumor patients included a diaphragmatic rupture and rib fractures along
the ultrasound pathway. Conclusion: The complications of HIFU develop mainly around the targeted lesions or along the ultrasound beam pathway. It is essential
to have awareness of the possible complications related to HIFU and its imaging features for to avoiding serious complications. 相似文献
958.
Warty dyskeratoma (WD) is a rare epidermal tumor that frequently arises as a papule or nodule on the head or neck of middle-aged or older persons. Histologically, it shows a cup-shaped keratin-filled invagination of an acanthotic epidermis, suprabasilar clefting with villi projecting into the clefts and acantholytic dyskeratotic cells are also present. The changes almost always involve a single hair follicle. We describe a distinctive case of WD that showed involvement of two adjoining follicles within a solitary lesion. 相似文献
959.
960.