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31.
Krishna K. Singh Yuxin Dong John T. Belisle Jeffrey Harder Vijay K. Arora Suman Laal 《Clinical and Vaccine Immunology : CVI》2005,12(2):354-358
Serum samples obtained from human immunodeficiency virus (HIV)-infected tuberculosis (TB) patients months prior to clinical TB were used to delineate the profile of Mycobacterium tuberculosis culture filtrate proteins recognized during subclinical TB. A subset of ~12 antigens was recognized by antibodies in these serum samples. Antibodies to two of these antigens (81 [88]-kDa malate synthase [GlcB] and MPT51) were present in serum samples obtained during incipient subclinical TB in 19 (~90%) of the 21 HIV-infected TB patients tested. These antigens will be useful for devising diagnostic tests that can identify HIV-positive individuals who are at a high risk for developing clinical TB. 相似文献
32.
It's all about sex: gender, lung development and lung disease. 总被引:1,自引:0,他引:1
Michelle A Carey Jeffrey W Card James W Voltz Samuel J Arbes Dori R Germolec Kenneth S Korach Darryl C Zeldin 《Trends in Endocrinology and Metabolism》2007,18(8):308-313
Accumulating evidence suggests that gender affects the incidence, susceptibility and severity of several lung diseases. Gender also influences lung development and physiology. Data from both human and animal studies indicate that sex hormones might contribute to disease pathogenesis or serve as protective factors, depending on the disease involved. In this review, the influence of gender and sex hormones on lung development and pathology will be discussed, with specific emphasis on pulmonary fibrosis, asthma and cancer. 相似文献
33.
34.
Jeffrey N Baldwin David M Scott Sangeeta Agrawal Jean K Bartek R Ellen Davis-Hall Thomas P Reardon Edward M DeSimone 《Substance Abuse》2006,27(3):27-37
Alcohol and other drug (AOD) use behaviors of health professions students (HPS) were assessed by surveying both university-based HPS and other nursing programs in a Midwestern state in 1999. Response was 2,646 (56.4%) of surveyed students. Family history of alcohol-related and drug-related problems were reported by 39.8% and 13.9%, respectively, with 42.6% of respondents reporting one or both. Among nursing respondents, 48.1%, 19.2% and 51.1%, respectively, reported family problems with alcohol, drugs, or one or both. Past-year alcohol use was comparable to undergraduate college students (UCS) nationally (83%); heavy drinking, tobacco and recreational drug use by HPS were lower. Past year drug use was highest among medical students. Marijuana was the predominant illicit drug; medical students and males most often reported use. Health professions educational systems should proactively address student AOD prevention, education and assistance needs. 相似文献
35.
The first 150 words of the full text of this article appear below. Key points. . . [Full Text of this Article]
Nerve agents
AChE inhibitionOther cholinesterasesPhysical propertiesLatency and toxicityPharmacological propertiesClinical manifestationsTreatmentPyridostigmineAtropinePralidoxime
- Chemical personal protective equipment must be wornwhen in contact with contaminated casualties.
- Recognizing theclinical features of chemical warfare agent poisoning allowssupportive treatment and appropriate antidotes to be promptlyadministered.
- The mnemonic DUMBELS describes the muscarinicfeatures of the nerve agent poisoning toxidrome.
- There areeffective antidotes for poisoning with nerve agents, blood agents(metabolic poisons), botulinum toxin and kolokol-1.
- There areno specific antidotes for blistering agents (vesicants) andchoking agents.