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1.
Many different strategies are used to recruit students into scientific research careers, including neuroscience research. These strategies are rarely based on knowledge about students; instead, activities are selected based on their ease of implementation. The goal of the LEARN Project is to encourage high school students into mental health science research using the theme of learning and memory. One intervention the authors developed is five Web-based biographies introducing students to contemporary neuroscientist role models studying learning and memory. To guide the design of this intervention, the authors created a survey to determine where students obtain career information and who and what influences their career selection. In a convenience sample of 124 students, the authors found that almost all students use the Internet for information about careers, in addition to consulting family members and teachers. Students' career selections are influenced most by family members, teachers, and people already in the field. The most important factors students look for in their future career are money, fun, and a good match between current interests and future careers. The data affirm the value of outreach efforts that go beyond students to include a broader audience of parents and teachers who play a critical role in career selection. 相似文献
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Zusammenfassung Die Sedimentationsraten der kompletten löslichen Hämagglutinine der Adenoviren wurden bei 16 Prototypen der Untergruppe II im Saccharose-Gradienten bestimmt. Die Werte waren für alle Viren ähnlich (65±10S). Dies bedeutet, daß die strukturellen Komponenten ebenfalls identisch sein dürften, also Dodecon (1).
Durchgeführt mit Unterstützung der Deutschen Forschungsgemeinschaft. 相似文献
Dodecon, the soluble hemagglutinin present in all adenovirus types of subgroup II
Summary The sedimentation rate of the soluble complete hemagglutinins of 16 prototype adenoviruses of subgroup II were determined by means of sucrose gradient centrifugation. The rates were similar for all types (65±10S), thus indicating that the structural components may also be identicali.e. dodecon (1).
Durchgeführt mit Unterstützung der Deutschen Forschungsgemeinschaft. 相似文献
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Flow cytometric analysis of cell proliferation dynamics in the B cell compartment of the mouse 总被引:20,自引:0,他引:20
Using a method which allows simultaneous flow cytometric detectionof cell surface markers and 5-bromo-2'-deoxyuridine (BrdU) incorporation,the distribution and proliferative behavior of B lineage subpopulationswas studied in intact adult mice. In the bone marrow we coulddefine two subsets of B cells on the basis of differential expressionof the pan-B cell marker B220 and of membrane-associated µand immunoglobulin heavy chains. B220dullµ+– Bcells were found to emerge from rapidly dividing cells and probablyrepresent B cells recently generated from B220dullµ–pie-B cells. In contrast, oniy few, If any, of the B220brightµ++B cells were labeled with BrdU after a period of 8 days, suggestingthat these cells represent long-lived B cells residing in thebone marrow. Analysis of BrdU-Incorporation into splenic B cellsshowed that only 20% of these cells had gone through cell divisionduring the preceding 8 days. Almost none of the B cells in theperitoneum, a large fraction of which belongs to the Ly1 B subset,were labeled with BrdU over a period of 7 days in 8-month-oldanimals. 相似文献
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Shielded p-silicon diodes, frequently applied in general photon-beam dosimetry, show certain imperfections when applied in the small photon fields occurring in stereotactic or intensity modulated radiotherapy (IMRT), in electron beams and in the buildup region of photon beam dose distributions. Using as a study object the shielded p-silicon diode PTW 60008, well known for its reliable performance in general photon dosimetry, we have identified these imperfections as effects of electron scattering at the metallic parts of the shielding. In order to overcome these difficulties a new, unshielded diode PTW 60012 has been designed and manufactured by PTW Freiburg. By comparison with reference detectors, such as thimble and plane-parallel ionization chambers and a diamond detector, we could show the absence of these imperfections. An excellent performance of the new unshielded diode for the special dosimetric tasks in small photon fields, electron beams and build-up regions of photon beams has been observed. The new diode also has an improved angular response. However, due to its over-response to low-energy scattered photons, its recommended range of use does not include output factor measurements in large photon fields, although this effect can be compensated by a thin auxiliary lead shield. 相似文献
7.
Merfort I 《Planta medica》1984,50(1):107-108
From the flowers of ARNICA CHAMISSONIS Less, subsp. FOLIOSA var. INCANA, the methylated flavonoids acacetin, pectolinarigenin, hispidulin, jaceosidin, 6-methoxykaempferol, and betuletol have been isolated and identified by spectroscopic methods. Except for acacetin, the same flavonoids were identified in the flowers of ARNICA MONTANA L. Betuletol was found for the first time in the family of Asteraceae. 相似文献
8.
Urinary pharmacokinetics of betalains following consumption of red beet juice in healthy humans. 总被引:1,自引:0,他引:1
Thomas Frank Florian Conrad Stintzing Reinhold Carle Irmgard Bitsch Daniela Quaas Gabriele Strass Roland Bitsch Michael Netzel 《Pharmacological research》2005,52(4):290-297
The aim of the present pilot study was to characterise the renal elimination of betalains after consumption of red beet juice (RBJ). Six healthy, non-smoking female volunteers were given a single oral dose of either 500 mL of a commercial RBJ containing 362.7 mg of betalains and 500 mL of tap water, respectively, in a sequential manner. Urine was collected in intervals up to 24 h post-dose. Renal excretion of betalains was determined spectrophotometrically and quantified as betanin-equivalents. In addition, the identity of individual compounds was confirmed by HPLC coupled with diode-array detection and positive ion electrospray mass spectrometry, respectively. The amount (mean+/-S.D.) of intact betalains (betanin and isobetanin) recovered in urine was 1001+/-273 microg corresponding to 0.28+/-0.08% of the administered dose. Maximum excretion rates were observed after a median tmax,R of 3.0 h (range 2.5-8.0 h) amounting to 91.7+/-30.1 microg/h. The terminal elimination rate constant (lambdaz) and the corresponding half-life were 0.097+/-0.021 h(-1) and 7.43+/-1.47 h, respectively. Using the lambdaz estimates obtained the expected total betalain amount excreted in urine was 1228+/-291 microg. Based on the results obtained it is assumed that either the bioavailability of the betalains is low or that renal clearance is a minor route of systemic elimination for these compounds. The urinary excretion rates of unmetabolised betalains were fast and appeared to be monoexponential suggesting a one-compartment model. In order to get a more complete picture of the pharmacokinetics and health-promoting properties of red beet betalains, quantitative data on betalain bioavailability should include measurements of unchanged compounds and their corresponding metabolites in plasma, urine and bile. 相似文献
9.
Irmgard Ziegler 《Monatsschrift für Kinderheilkunde》1965,56(1):1-66
Ohne Zusammenfassung
Mit 5 Abbildungen 相似文献
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