全文获取类型
收费全文 | 180篇 |
免费 | 9篇 |
国内免费 | 1篇 |
专业分类
儿科学 | 3篇 |
妇产科学 | 14篇 |
基础医学 | 21篇 |
口腔科学 | 4篇 |
临床医学 | 16篇 |
内科学 | 12篇 |
皮肤病学 | 5篇 |
神经病学 | 35篇 |
特种医学 | 4篇 |
外科学 | 28篇 |
综合类 | 3篇 |
预防医学 | 12篇 |
眼科学 | 1篇 |
药学 | 18篇 |
肿瘤学 | 14篇 |
出版年
2023年 | 2篇 |
2022年 | 5篇 |
2021年 | 13篇 |
2020年 | 4篇 |
2019年 | 10篇 |
2018年 | 5篇 |
2016年 | 12篇 |
2015年 | 7篇 |
2014年 | 15篇 |
2013年 | 17篇 |
2012年 | 7篇 |
2011年 | 8篇 |
2010年 | 4篇 |
2009年 | 3篇 |
2008年 | 18篇 |
2007年 | 10篇 |
2006年 | 8篇 |
2005年 | 8篇 |
2004年 | 14篇 |
2003年 | 4篇 |
2002年 | 7篇 |
2000年 | 1篇 |
1998年 | 1篇 |
1997年 | 2篇 |
1996年 | 1篇 |
1995年 | 1篇 |
1994年 | 1篇 |
1992年 | 2篇 |
排序方式: 共有190条查询结果,搜索用时 0 毫秒
51.
52.
Rashid F Ahmed R Mahmood A Ahmad Z Bibi N Kazmi SU 《Archives of pharmacal research》2007,30(8):932-937
Investigations on the chemical constituents of the fruits of Prunus armeniaca have led to the isolation of two new flavonoid glycosides, 4',5,7-trihydroxy flavone-7-O-[beta-D-mannopyranosyl (1'-->2")]-beta-D-allopyranoside (1) and 3,4',5,7-tetrahydroxy-3',5'-di-methoxy flavone 3-O-[alpha-L-rhamnopyranosyl (1'-->6")]-beta-D-galactopyranoside (2), from the butanolic fraction of the fruits. The butanolic extract exhibited antibacterial activity against both Gram positive and Gram negative bacteria. The structures of these compounds were elucidated through spectral studies, including 2D-NMR (COSY, NOESY, J-resolved), HMQC and HMBC experiments. 相似文献
53.
Megan E. Reller Anita K. M. Zaidi Shazia Sultana Shazia Azeem Beenish Hanif Shahida Qureshi Rumina Hasan Zulfiqar Bhutta Rehana Akhter Donald A. Goldmann 《Journal of clinical microbiology》2009,47(1):245-246
We compared anaerobic lytic (AL) and pediatric aerobic resin-containing (Peds Plus/F) blood culture media for the isolation of Salmonella enterica serotype Typhi or Paratyphi A from children. The yields from AL and Peds Plus/F media were the same with equal volumes of blood, but recovery was faster from AL medium than Peds Plus/F medium (10.7 and 16.4 h, respectively) (P < 0.001). 相似文献
54.
Ratts RB Lovett-Racke AE Choy J Northrop SC Hussain RZ Karandikar NJ Racke MK 《Journal of neuroimmunology》2006,178(1-2):117-129
Human T cells adopt a CD28-CD57+ phenotype in chronic viral infections and this has been hypothesized to result from continuous stimulation, however this phenotype may be due to direct viral effects on T cells. Employing MS patients before and after chronic in vivo administration of the antigen glatiramer acetate (GA) we examine this hypothesis. Pre-treatment glatiramer acetate-specific CD8 T cells were CD57-Perforin-. This changed to a predominantly CD28-CD57+Perforin+ response after administration of this drug. This phenotype was only observed after chronic stimulation and not in a recall response to mumps. The relevance to GA's mechanism of action is discussed. 相似文献
55.
Hansen BS Hussain RZ Lovett-Racke AE Thomas JA Racke MK 《Journal of neuroimmunology》2006,172(1-2):94-103
Infections can trigger or exacerbate the course of Multiple Sclerosis, and both bacterial and viral agents have been implicated. These agents are recognized by host cells via pathogen-associated molecular patterns activating TLRs. We investigated the role that PAMPs play in the animal model Experimental Autoimmune Encephalomyelitis, and found various MyD88-dependent PAMPs can participate as the adjuvant to induce EAE. Studies with IRAK1-deficient mice suggest that signaling through TLRs is not required in the target organ to develop disease. This suggests that PAMPs play an important role in priming of autoreactive T cells in EAE and potentially MS. 相似文献
56.
57.
Yabe I Matsushima M Soma H Basri R Sasaki H 《Journal of the neurological sciences》2008,266(1-2):164-166
In this study, we examined the usefulness and validity of the Scale for the Assessment and Rating of Ataxia (SARA) in assessing cerebellar ataxia in 27 patients with spinocerebellar degeneration. The inter-rater reliability of the SARA scores between the two neurologists was high. The scores on SARA correlated significantly with the Barthel index and scores on the International Cooperative Ataxia Rating Scale (ICARS). Scores on ICARS and SARA did not correlate with the total length traveled (TLT) or the root mean square area (RMS) of body sways measured by body stabilometry. The time required to examine each patient for SARA was approximately 4 min, one-third the time required for ICARS. Our results indicate that SARA is useful for the evaluation of cerebellar ataxic patients in daily examinations and that body sway analysis by stabilometry is influenced by factors other than cerebellar ataxia, such as muscle weakness, which should be taken into account when body sway analysis is used to evaluate the severity of cerebellar ataxia. 相似文献
58.
59.
Shinwari Rehana Wilson Michael Lowery Abiodun Olumide Shaikh Masood Ali 《Archives of women's mental health》2022,25(1):95-105
Archives of Women's Mental Health - Intimate partner violence (IPV) is one of the most prevalent forms of violence that women suffer globally. Women in Afghanistan have been exposed to high... 相似文献
60.
Kathryn H Schmitz Rehana L Ahmed Douglas Yee 《Cancer epidemiology, biomarkers & prevention》2002,11(12):1597-1604
We assessed the effects of twice weekly strength training on several proposed risk factors for breast and colon cancer: body fat, waist circumference, fasting insulin, fasting glucose, insulin-like growth factor I (IGF-I), and several IGF-binding proteins. Fifty-four healthy women, 30-50 years old, were randomized to no-contact control or treatment: 15 weeks of supervised strength training followed by 6 months of unsupervised training. Fifteen-week changes included reductions in percentage of body fat, fasting insulin, fasting glucose, and IGF-I that were larger in the treatment than control participants (treatment versus control mean +/- SE: % body fat -1.97 +/- 0.42 versus -0.43 +/- 0.40, P = 0.01; insulin (uU/ml) -0.29 +/- 0.35 versus 0.81 +/- 0.38, P = 0.055; glucose (mg/dl) -1.92 +/- 1.27 versus 1.21 +/- 1.36, P = 0.13; and IGF-I (ng/ml) -30.47 +/- 9.75 versus 5.86 +/- 10.44, P = 0.02). There was no treatment effect on IGF-binding proteins 1 and 3 or either of two surrogate measures of free IGF-I. By 39 weeks changes in percentages of body fat were largely maintained; IGF-I returned to baseline levels in the treatment group but remained 15% lower in treatment compared with control participants. Strength training produced favorable changes in several proposed cancer risk factors. The importance of these changes to long-term cancer prognosis, diagnosis, and/or recurrence remains to be determined. 相似文献