全文获取类型
收费全文 | 13681篇 |
免费 | 762篇 |
国内免费 | 126篇 |
专业分类
耳鼻咽喉 | 284篇 |
儿科学 | 238篇 |
妇产科学 | 336篇 |
基础医学 | 2011篇 |
口腔科学 | 387篇 |
临床医学 | 1136篇 |
内科学 | 2740篇 |
皮肤病学 | 252篇 |
神经病学 | 1069篇 |
特种医学 | 638篇 |
外科学 | 1858篇 |
综合类 | 156篇 |
一般理论 | 1篇 |
预防医学 | 752篇 |
眼科学 | 430篇 |
药学 | 1173篇 |
中国医学 | 169篇 |
肿瘤学 | 939篇 |
出版年
2023年 | 97篇 |
2022年 | 245篇 |
2021年 | 465篇 |
2020年 | 202篇 |
2019年 | 329篇 |
2018年 | 432篇 |
2017年 | 301篇 |
2016年 | 391篇 |
2015年 | 573篇 |
2014年 | 640篇 |
2013年 | 854篇 |
2012年 | 1277篇 |
2011年 | 1200篇 |
2010年 | 669篇 |
2009年 | 559篇 |
2008年 | 797篇 |
2007年 | 728篇 |
2006年 | 713篇 |
2005年 | 617篇 |
2004年 | 552篇 |
2003年 | 457篇 |
2002年 | 407篇 |
2001年 | 368篇 |
2000年 | 320篇 |
1999年 | 235篇 |
1998年 | 86篇 |
1997年 | 49篇 |
1996年 | 37篇 |
1995年 | 46篇 |
1994年 | 41篇 |
1993年 | 39篇 |
1992年 | 114篇 |
1991年 | 88篇 |
1990年 | 84篇 |
1989年 | 87篇 |
1988年 | 71篇 |
1987年 | 61篇 |
1986年 | 51篇 |
1985年 | 49篇 |
1984年 | 29篇 |
1983年 | 28篇 |
1982年 | 20篇 |
1980年 | 13篇 |
1979年 | 13篇 |
1978年 | 16篇 |
1977年 | 13篇 |
1976年 | 11篇 |
1975年 | 14篇 |
1974年 | 17篇 |
1973年 | 10篇 |
排序方式: 共有10000条查询结果,搜索用时 9 毫秒
991.
992.
993.
Brian H. Tran T. JoAnna Nguyen Brian H. Hwang Evan N. Vidar Gabrielle B. Davis Linda S. Chan Karen Woo Alex K. Wong 《Breast (Edinburgh, Scotland)》2013,22(4):444-448
Venous thromboembolism (VTE) is a potentially preventable disease that carries significant morbidity and mortality. Although malignancy is associated with increased risk for VTE, it varies according to cancer type. Despite the fact that breast cancer is the most common form of cancer in women, the incidence and risk factors associated with VTE in patients undergoing mastectomy have not been well characterized. To address this we utilized the ACS-NSQIP database to identify and characterize independent risk factors for VTE in 49,028 mastectomy patients. We identified 116 cases of VTE in the 49,028 cases analyzed (0.23%). Obesity (BMI > 30, OR = 1.91, p < 0.001), inpatient status (OR = 3.75, p < 0.001), venous catheterization (OR = 2.67, p = 0.012), prolonged operative time >3 h (OR = 4.36, p < 0.001), and immediate reconstruction (OR = 3.23, p < 0.001) were found to be independent risk factors for VTE. While the incidence of VTE is rare in mastectomy patients, the heightened awareness and increased VTE prophylaxis should be considered in high risk groups. 相似文献
994.
Yoon Jin Hwang Bong Hyun Chang Jun Woo Kim Gyu Seog Choi Young Kook Yun Albert Chui Yang Ii Kim 《Journal of Hepato-Biliary-Pancreatic Surgery》1999,6(3):320-323
Resection is the best hope for the cure of colorectal metastasis to the liver. However, surgery is indicated for only a few
patients, especially those who have major vascular involvement. We report a 55-year-old woman with a liver metastasis from
the cecum that showed a tumor thrombus in the right side of the heart. She had undergone laparoscopic right hemicolectomy
for cecal cancer 6 months before, and presented with a palpable mass in the epigastrium. Abdominal ultrasonography, computed
tomography, hepatic angiogram, and echocardiography showed a huge mass on the left lobe of the liver, with a tumor thrombus
which extended to the right ventricle through the left hepatic vein and inferior vena cava. Tumor thrombectomy, through a
right atriotomy, was success-fully performed under cardiopulmonary bypass, followed by left hepatic lobectomy. The patient's
postoperative course was uneventful.
Received for publication on Oct. 5, 1998; accepted on Jan. 11, 1999 相似文献
995.
Chun-Nan Yeh Hsiang-Lin Lee Yu-Yin Liu Kun-Chun Chiang Tsann-Long Hwang Yi-Yin Jan Miin-Fu Chen 《Langenbeck's archives of surgery / Deutsche Gesellschaft fur Chirurgie》2008,393(6):849-855
Background We conducted a prospective and case-controlled study to evaluate the impact of supplement of alanyl-glutamine dipeptide (Gln)
in parenteral nutrition on perioperative immune and nutritional changes and clinical outcomes for patients undergoing gastrointestinal
(GI) operations.
Materials and methods During 2006, 70 patients undergoing GI surgeries were allocated equally into two groups. One group received regular parenteral
nutrition and the other received the same formulation and supplemented with the Gln; the two groups were isonitrogenous. The
infusion was started from 1 day before operation to the sixth day after operation for 7 days. Blood samples were collected
on the morning of the day before the operation and on the morning 6 days after the operation and analyzed for immune and nutrition
parameters.
Results There were no differences between the two groups in terms of clinical characteristics, operative procedures, biochemistry,
nutritional status, and immune status preoperatively. After GI surgery, significant reduction in nutritional and immune parameters
were observed in both groups, demonstrated by significant difference of albumin, C-reactive protein (CRP), lymphocyte count,
T cell, and CD8 cell. The length of hospital stay is slightly longer in the control group patients, but not to statistical
significance (16.3 ± 21.3 versus 12.2 ± 6.8 days, p = 0.299). In terms of morbidity, there was no difference between the two groups, but two patients in the control group had
wound infection; none was noted in the Gln group (p = 1.0). No surgical mortality was noted in this study.
Conclusions Perioperative parenteral nutrition supplemented with Gln is beneficial for patients undergoing GI surgery. Gln supplementation
significantly attenuated postoperative inflammation and ameliorated postoperative immunodepression as well as nutritional
depression in GI surgery. 相似文献
996.
Tae-Hee Han Cheol-Hwan Kim Ju-Young Chung Sang-Hun Park Eung-Soo Hwang 《Emerging infectious diseases》2010,16(10):1623-1625
To investigate prevalence and clinical characteristics of klassevirus in South Korea, we performed molecular screening in fecal and nasopharyngeal samples from hospitalized children with gastroenteritis. A total of 26 (8.8%) of 294 fecal samples were positive for klassevirus. Klassevirus may be a possible cause of gastroenteritis. 相似文献
997.
The uterus is an unusual site for metastasis from an extrapelvic neoplasm. We report a case of uterine metastasis with extensive calcification. Plain radiography, ultrasonography and CT showed diffuse calcification within the uterine wall and T2-weighted MR images showed abnormally high signal intensity of the entire myometrium. 相似文献
998.
M H Hwang Z E Piao D K Murdock J J Giardina I Pacold H S Loeb C V Reyes P J Scanlon 《Catheterization and cardiovascular diagnosis》1989,16(3):209-213
The influence of contrast media on coagulation has an important association with thromboembolic complication during coronary angiography. In this study, whole blood was methodically mixed with nonionic contrast medium, Iohexol (IOH), conventional ionic contrast medium, Hypaque-76 (H76), and low osmolar ionic dimer Hexabrix (HB) in vitro. The thrombotic propensity of contrast agents can be evaluated by measuring the clot formation of the mixtures. The experiments were repeated with whole blood after systemic heparinization. In the in vitro study, 5 ml of canine (N = 10) and 3 ml of human (N = 11) whole blood was incubated for 30 min in glass tubes with equal volumes of IOH, H76, HB, and 0.9% NaCl before heparinization. Clot formation with IOH and 0.9% NaCl were seen both in dogs (4.0 +/- 0.7 gm and 5.6 +/- 0.8 gm) and in patients (1.4 +/- 0.9 gm and 2.9 +/- 1.3 gm), whereas no clot was seen with H76 or XB. Following heparinization, no clot was visualized in any mixture of whole blood with contrast media or 0.9% NaCl. Similar results were observed in the catheter-syringe system with canine blood (N = 11) mixed with the contrast agents. Blood clots found in 15 min and 30 min of IOH were 0.07 +/- 0.08 gm and 0.44 +/- 0.20 gm (P less than 0.01) and of NaCl were 0.29 +/- 0.37 gm and 0.69 +/- 0.38 gm (P less than 0.01).(ABSTRACT TRUNCATED AT 250 WORDS) 相似文献
999.
The responses to slow constant velocity rotations in the clockwise (CW) and counterclockwise (CCW) directions about an axis tilted 10 degrees from the earth's vertical were studied in static tilt-sensitive neurons in the vestibular nuclei of decerebrate cats. Each unit responded to any 360 degrees unidirectional rotation with a position-dependent discharge maximum. The location of the maximum, obtained by rotation in one direction, differed from that obtained by an oppositely directed rotation (phase difference). In about 80% of the units such phase difference (up to 160 degrees in second-order neurons) in response to oppositely directed rotations was unaffected by different amplitudes of head displacement (5-25 degrees). Units were thus classified into two groups depending on the location of the CW discharge maximum relative to the CCW counterpart. The direction of rotation had no influence on the response gains of these units. 相似文献
1000.
Catecholaminergic (CA) nerve terminals in the paraventricular hypothalamic nucleus (PVN) of adult rats were studied at 4, 21, 56 and 180 days after a single injection of 6-hydroxydopamine (6-OHDA) neurotoxin into the right lateral ventricle of the brain. We previously described and quantified the extent of CA terminal sprouting in the PVN after 6-OHDA lesions. For this communication we studied parameters, specifically the bouton sizes and the synaptic frequencies of CA terminals during the renewal process, and evaluated how changes of these parameters are related to axonal sprouting. The CA boutons were identifiable in the electron microscope by exhibiting small granular vesicles (SGVs) after central administration of 5-hydroxydopamine (5-OHDA) marker. The marked CA boutons were measured and further categorized according to whether or not they were associated with distinct synaptic specializations at various post-lesion stages. The average sizes of CA boutons were strikingly similar in their diameters (1.0 micron) for both control and experimental tissues. However, CA boutons larger than 2.1 micron were rare and seen more often in the experimental tissues with 6-OHDA lesion and were sustained up to 180 days after lesions. Catecholaminergic profiles with ultrastructural features of growth cones were also seen in the PVN following the 6-OHDA lesions, indicating that there is growth activity in the PVN after 6-OHDA lesion. There were 33% of CA boutons in the PVN from the control tissues that appeared to have synaptic contacts.(ABSTRACT TRUNCATED AT 250 WORDS) 相似文献