Pulmonary toxicity of inhaled and intravenous talc

Talc (magnesium silicate) is a widely used, generally considered benign substance. It is principally used as an inert filler material in drug tablets or as a drying ingredient in baby powders. However, in both cases inappropriate use can lead to severe pulmonary toxicological responses. On the one hand, intravenous injection of 'solubilized', CNS active pills can produce microemboli in small pulmonary vessels. This can lead to various degrees of granuloma formation, compromised pulmonary function, or death. Overzealous application of baby powder can also produce severe pulmonary complications if the infant inspires the powder. Although the data are relatively scarce, a number of reports suggest the existence of a chronic problem in this area.     

Training Occupational Therapy Managers

There is a need for occupational therapists to become competent managers in a diverse range of health care settings. In this paper, the author's continuing education course on management which they have conducted at the West Australian Institute of Technology (now Curtin University of Technology) over the past four years. Details of participants, their reasons for attending and their comments on the course are included. The authors emphasise the need for more continuing education in management and the provision of skills for coping with organisational life, in particular in a female dominated profession such as occupational therapy.     

Productive Aging: A Quality of Life Agenda

Although the fact that, in general, the US population is living longer is said to be the public health success story of the 20th century, the boom in the population aged 65 years and older is having and will continue to have major implications for all age groups as well as for the nation's health, social, and economic institutions. The concept of productive aging can provide guidance in addressing these implications. The assumptions of productive aging reflect today's reality that older people are repositories of wisdom and experience and important assets for society; relatively healthy, with the potential for maintaining that condition until late in life; capable of making economic and social contributions that benefit themselves, their families, and their communities; and in need of purposeful and meaningful roles and activities in life. A productive aging activity model emphasizes involvement in paid work, volunteerism, education, fitness and exercise, leisure and travel, advocacy and political action, and consumerism. This article discusses the concept of productive aging, a related activity model, and qualitative focus group research undertaken in conjunction with the 1995 White House Conference on Aging. J Am Diet Assoc. 1998;98:1445–1448.     

Non-A, non-B hepatitis and antibody to hepatitis C virus

Stored serum samples from the Transfusion-transmitted Viruses Study in the 1970s were tested for the presence of antibody to hepatitis C virus (anti-HCV). Single specimens from five control subjects who did not receive transfusions tested negative for anti-HCV. Of four control subjects who did not receive transfusions and who developed non-A, non-B (NANB) hepatitis after hospitalization, three remained anti-HCV negative; the fourth person with postoperative NANB hepatitis tested anti-HCV positive before the operation. Five transfusion recipients with posttransfusion hepatitis B virus infection remained seronegative; a sixth with NANB hepatitis as well as hepatitis B virus infection had seroconversion for anti-HCV. Five of nine transfusion recipients with NANB hepatitis had anti-HCV seroconversion. These results show that present anti-HCV testing demonstrates an etiologic basis for approximately half of the cases of transfusion-associated NANB hepatitis, particularly those that develop chronicity. Although cases of NANB hepatitis without seroconversion may be explained otherwise, they may be caused by another, presently unidentified, virus.