全文获取类型
收费全文 | 403190篇 |
免费 | 26116篇 |
国内免费 | 2867篇 |
专业分类
耳鼻咽喉 | 5538篇 |
儿科学 | 10198篇 |
妇产科学 | 10682篇 |
基础医学 | 55950篇 |
口腔科学 | 12218篇 |
临床医学 | 31449篇 |
内科学 | 82855篇 |
皮肤病学 | 9517篇 |
神经病学 | 28289篇 |
特种医学 | 14829篇 |
外国民族医学 | 82篇 |
外科学 | 64329篇 |
综合类 | 10850篇 |
现状与发展 | 1篇 |
一般理论 | 74篇 |
预防医学 | 18648篇 |
眼科学 | 10702篇 |
药学 | 32954篇 |
1篇 | |
中国医学 | 2321篇 |
肿瘤学 | 30686篇 |
出版年
2021年 | 3306篇 |
2019年 | 3177篇 |
2018年 | 5177篇 |
2017年 | 3868篇 |
2016年 | 4151篇 |
2015年 | 4572篇 |
2014年 | 6577篇 |
2013年 | 8416篇 |
2012年 | 11489篇 |
2011年 | 11768篇 |
2010年 | 7038篇 |
2009年 | 6531篇 |
2008年 | 10637篇 |
2007年 | 11529篇 |
2006年 | 11277篇 |
2005年 | 10292篇 |
2004年 | 9699篇 |
2003年 | 9363篇 |
2002年 | 8950篇 |
2001年 | 28937篇 |
2000年 | 29430篇 |
1999年 | 24220篇 |
1998年 | 5393篇 |
1997年 | 4422篇 |
1996年 | 3966篇 |
1995年 | 3606篇 |
1994年 | 3214篇 |
1993年 | 2971篇 |
1992年 | 16388篇 |
1991年 | 15183篇 |
1990年 | 14484篇 |
1989年 | 14303篇 |
1988年 | 12876篇 |
1987年 | 12327篇 |
1986年 | 11363篇 |
1985年 | 10590篇 |
1984年 | 7127篇 |
1983年 | 5775篇 |
1982年 | 2824篇 |
1979年 | 5715篇 |
1978年 | 3503篇 |
1977年 | 3117篇 |
1976年 | 2372篇 |
1975年 | 2796篇 |
1974年 | 3216篇 |
1973年 | 3041篇 |
1972年 | 2964篇 |
1971年 | 2893篇 |
1970年 | 2618篇 |
1969年 | 2643篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
11.
Loss‐of‐function mutations in the gene encoding filaggrin underlie a Japanese family with food‐dependent exercise‐induced anaphylaxis 下载免费PDF全文
12.
Y.R. Song B. Wu Y.T. Yang J. Chen L.J. Zhang Z.W. Zhang H.Y. Shi C.L. Huang J.X. Pan P. Xie 《Brazilian journal of medical and biological research》2015,48(11):973-982
Bipolar disorder (BD) is a common psychiatric mood disorder affecting more than 1-2%
of the general population of different European countries. Unfortunately, there is no
objective laboratory-based test to aid BD diagnosis or monitor its progression, and
little is known about the molecular basis of BD. Here, we performed a comparative
proteomic study to identify differentially expressed plasma proteins in various BD
mood states (depressed BD, manic BD, and euthymic BD) relative to healthy controls. A
total of 10 euthymic BD, 20 depressed BD, 15 manic BD, and 20 demographically matched
healthy control subjects were recruited. Seven high-abundance proteins were
immunodepleted in plasma samples from the 4 experimental groups, which were then
subjected to proteome-wide expression profiling by two-dimensional electrophoresis
and matrix-assisted laser desorption/ionization-time-of-flight/time-of-flight tandem
mass spectrometry. Proteomic results were validated by immunoblotting and
bioinformatically analyzed using MetaCore. From a total of 32 proteins identified
with 1.5-fold changes in expression compared with healthy controls, 16 proteins were
perturbed in BD independent of mood state, while 16 proteins were specifically
associated with particular BD mood states. Two mood-independent differential
proteins, apolipoprotein (Apo) A1 and Apo L1, suggest that BD pathophysiology may be
associated with early perturbations in lipid metabolism. Moreover, down-regulation of
one mood-dependent protein, carbonic anhydrase 1 (CA-1), suggests it may be involved
in the pathophysiology of depressive episodes in BD. Thus, BD pathophysiology may be
associated with early perturbations in lipid metabolism that are independent of mood
state, while CA-1 may be involved in the pathophysiology of depressive episodes. 相似文献
13.
14.
15.
Nevo N. Goldstein A. L. Staierman M. Eran N. Carmeli I. Rayman S. mnouskin Y. 《Hernia》2022,26(6):1491-1499
Hernia - The minimally invasive surgical repair of combined inguinal and ventral hernias often requires shifting from one approach or plane to another. The traditional enhanced-view totally... 相似文献
16.
17.
18.
Gupta Archana A. Mammo Danny A. Page Michael A. 《Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie》2020,258(1):167-173
Graefe's Archive for Clinical and Experimental Ophthalmology - To evaluate the long-term safety and efficacy of intrastromal bevacizumab for treatment of deep corneal neovascularization in... 相似文献
19.
20.
L.‐Q. Zheng X.‐C. Han Y. Huang H.‐W. Li X.‐D. Niu J. Li 《Clinical and experimental dermatology》2015,40(3):293-297
Porocarcinoma is an unusual, locally aggressive and potentially fatal neoplasm. Several cutaneous malignancies have been described in association with porocarcinoma, including squamous cell carcinoma, basal cell carcinoma and tricholemmal carcinoma. Previous reports have indicated that the occurrence of malignant tumours in combination with porocarcinoma is extremely rare, in particular with regard to Bowen disease (BD). We report an uncommon case of porocarcinoma occurring synchronously in a single BD lesion in a 63‐year‐old woman with multiple BD lesions. The clinical and histological findings confirmed this diagnosis. 相似文献