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排序方式: 共有1312条查询结果,搜索用时 15 毫秒
41.
da Costa Iwyson Henrique Fernandes Silva Renan Morais e Carlos Juliana de Oliveira Silva Maria Cleonice Araújo Pinheiro Maria Karine Cavalcante Martins Bruna Cristina Cardoso Fernandes Paula Frassinetti Castelo Branco Camurça Guedes Marjorie Moreira 《International journal of clinical pharmacy》2019,41(4):888-894
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43.
Andréia Guedes Oliva Fernandes Carolina Souza-Machado Renata Concei??o Pereira Coelho Priscila Abreu Franco Renata Miranda Esquivel Adelmir Souza-Machado álvaro Augusto Cruz 《Jornal brasileiro de pneumologia》2014,40(4):364-372
OBJECTIVE:
To identify risk factors for death among patients with severe asthma.METHODS:
This was a nested case-control study. Among the patients with severe asthma treated between December of 2002 and December of 2010 at the Central Referral Outpatient Clinic of the Bahia State Asthma Control Program, in the city of Salvador, Brazil, we selected all those who died, as well as selecting other patients with severe asthma to be used as controls (at a ratio of 1:4). Data were collected from the medical charts of the patients, home visit reports, and death certificates.RESULTS:
We selected 58 cases of deaths and 232 control cases. Most of the deaths were attributed to respiratory causes and occurred within a health care facility. Advanced age, unemployment, rhinitis, symptoms of gastroesophageal reflux disease, long-standing asthma, and persistent airflow obstruction were common features in both groups. Multivariate analysis showed that male gender, FEV1 pre-bronchodilator < 60% of predicted, and the lack of control of asthma symptoms were significantly and independently associated with mortality in this sample of patients with severe asthma.CONCLUSIONS:
In this cohort of outpatients with severe asthma, the deaths occurred predominantly due to respiratory causes and within a health care facility. Lack of asthma control and male gender were risk factors for mortality. 相似文献44.
Gleber-Netto FO Florêncio TN de Sousa SF Abreu MH Mendon?a EF Aguiar MC 《Journal of oral pathology & medicine》2012,41(8):603-609
J Oral Pathol Med (2012) 41: 603-609 Background: Mucoepidermoid carcinoma is the most common malignant tumor of salivary glands. This tumor is characterized by a great variability in clinical behavior, and little is known about the pathological mechanisms involved in its variance. Angiogenesis is an important step in tumor progression and is believed to be an essential event for metastatic dissemination. Methods: We aimed to investigate angiogenesis and lymphangiogenesis in mucoepidermoid carcinoma measuring the density of neoformed and lymphatic vessels using CD105 and D2-40 antibodies, respectively, and by immunohistochemical evaluation of VEGF-A and VEGF-C proteins. It was also investigated the expression of D2-40 in neoplastic cells. Results: We studied 26 cases of mucoepidermoid carcinoma, which showed great angiogenic activity measured by neoformed vessel density. However, a low density of lymphatics was observed. VEGF-A, VEGF-C, and D2-40 were commonly detected in mucoepidermoid carcinoma, but only VEGF-A expression correlated with neoformed vessel density. Recurrence and nodal metastasis were associated with low VEGF-A expression and low neoformed vessel density, indicating that impaired angiogenesis could lead to an aggressive phenotype. Conclusions: Angiogenesis seems important in the modulation of mucoepidermoid carcinoma pathogenesis; however, none of the parameters analyzed could predict tumor behavior. 相似文献
45.
de Oliveira JA do Amaral Escada AL Alves Rezende MC Mathor MB Alves Claro AP 《Clinical oral implants research》2012,23(4):511-514
Objective: The purpose of the present study was to evaluate the influence of radiation in osseointegrated dental implants installed in tibiae of rats. Material and methods: Screw‐shaped implants (2.5 mm diameter by 3.5 mm length) were custom made from commercially pure titanium bars. Titanium implants were blasted and sterilized before implantation. Animals were divided into two groups of 12 animals each and the rats were not paired after the groups' formation. The experimental group (group 1) received external irradiation 4 weeks after surgery while in the control group (group 2) animals were kept free of radiation. The shear strength required to detach the implant from bone was measured by push‐out testing and osseointegration was histologically evaluated. Results: Results showed that the compressive strength of irradiated implants (33.49 MPa) was significantly lower than the compressive strength of non‐irradiated implants (48.05 MPa). Conclusions: We concluded that the mechanical strength bonding between implants and host tissues decreased after irradiation. To cite this article: Oliveira JAG, Escada ALA, Alves Rezende MCR, Mathor MB, Alves Claro APR. Analysis of the effects of irradiation in osseointegrated dental implants.Clin. Oral Impl. Res. 23 , 2012 511–514.doi: 10.1111/j.1600‐0501.2010.02149.x 相似文献
46.
47.
AP Mishreki E Lim P Cranefield S Pascoe S Jackson DA Stell 《Annals of the Royal College of Surgeons of England》2013,95(5):349-352
Introduction
The results of surgical resection and palliative chemotherapy use in hilar cholangiocarcinoma (HC) have been well publicised but the proportion of patients able to undergo these treatments and the comparative outcomes in a population of patients with HC are less well known.Methods
Patients with HC were identified by review of all patients undergoing percutaneous cholangiography over a nine-year period (2002–2010) in a tertiary facility. The treatment undertaken and outcomes were recorded.Results
Overall, 68 patients were identified (37 female) with a median age of 70 years. Forty-five (66%) were treated solely by insertion of a metal stent (median survival 4.73 months) and nine (13%) also received palliative chemotherapy (median survival 13.7 months). Persisting jaundice after stent insertion was noted in 18 of 35 patients (51%) tested within one month of death. Fourteen patients (21%) underwent surgical resection (median survival 20.2 months).Conclusions
Patients undergoing surgical resection had significantly longer survival than those receiving only a palliative stent but not compared with those also receiving palliative chemotherapy, with short-term follow-up. Only a third of patients, however, receive active treatment (surgery or chemotherapy) and improvements in long-term biliary palliation are needed. 相似文献48.
49.
Piovesan C Antunes JL Mendes FM Guedes RS Ardenghi TM 《Journal of public health dentistry》2012,72(2):156-163
Objective: This study assessed the relation of child oral health‐related quality of life with school performance and school absenteeism. Methods: We followed a cross‐sectional design with a multistage random sample of 312 12‐year‐old schoolchildren living in Brazil. The participants completed the child perceptions questionnaire (CPQ11–14) that provides information about psychological factors, while their parents or guardians answered questions on their socioeconomic status measured by parents' education level and household income. A dental examination of each child provided information on the prevalence of caries and dental trauma. Data on school performance, which included the results of baseline Brazilian language (Portuguese) tests, and school absenteeism (school days missed) were obtained from the school register. Multilevel linear regression was used to investigate the association among psychological and socioeconomic status and children's school performance. Results: In the multiple model, after adjusting for individual covariates, being a girl was associated with higher school performance (P < 0.05), whereas low household income (P < 0.05), higher mean of CPQ11–14 (P < 0.05), and higher school days missed (P < 0.001) were identified as individual determinants of lower school performance. When the school‐level covariates were included in the model, the association between subjects' level characteristics and school performance still persisted. Conclusion: Children's school performance and absence were influenced by psychological and socioeconomic conditions. 相似文献
50.
Lucieni Oliveira Conterno Silvana Martins Dias Toni Rubiana Gon?alves Konkiewitz Elaine Salla Guedes Rubens Tofano de Barros Marcos Gradim Tiveron 《Brazilian Journal Of Cardiovascular Surgery》2014,29(2):167-176