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Summary. The vagina is a common source of non-sporing anaerobic bacteria which may be the cause of postoperative infection after hysterectomy. A single vaginal pessary containing 1 g of metronidazole inserted the night before abdominal hysterectomy reduced the mean duration of postoperative pyrexia from 15·4 to 8·3 h ( P <0·05).  相似文献   
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The Health of Subjects Living with a Permanent Ileostomy   总被引:5,自引:0,他引:5  
The alms of the present study were to survey the general stateof health of a group of fleostomists, including social, psychologicaland sexual aspects, and to investigate a range of metabolicfunctions in the same patients. The subjects studied were takenat random from patients who had been treated by proctocolectomyand ileostomy in Oxford. There were 39 subjects whose operationhad been performed for ulcerative colitis and 12 subjects whohad had the operation for Crohn's disease involving the colon.A control group consisting of 39 healthy volunteers, matchedfor age and sex with the 39 patients who had had ulcerativecolitis were also studied. The general health of the ileostomists,as judged by their medical history, the findings on completephysical examination and the results of standard biochemicaland haematological investigations was good or excellent Virtuallyall were pursuing their normal occupations. Most of them enjoyedtheir normal recreations but several had given up swimming.An appreciable number considered that they had received inadequateexplanation and guidance before and after the institution ofthe ileostomy. Psychological abnormalities, as judged by responsesto standard inventories, were minor. There was little evidenceof physical impairment of sexual activity but psychologicalproblems were not unusual . The dietary habits of the ileostomists were essentially normalbut they consumed more fluid and more salt than the controlsubjects. In spite of this, the ileostomists showed evidenceof mild dehydration and aldosteronism. It is recommended thatan Qeostomist should consume 15 ml/Kg body weight of additionalfluid and 100 mg/Kg body weight of additional salt each day.There was a mild degree of iron deficiency which was correctibleby oral supplements. Vitamin B12 absorption was enhanced inthe ileostomists who had had ulcerative colitis. There was noevidence of folate depletion. The ileostomists had increasedretention of calcium. This suggests that they were probablydeficient in calcium at the time of operation and were slowlycorrecting the deficit. Male ileostomists had a high incidenceof urinary stones, possibly related to a low pH and volume ofthe urine and a high level of plasma uric acid. The ileostomistshad a high incidence of gallstones. The gastrointestinal hormoneprofile in the fleostomists showed significant differences fromnormal in the values of motflin, en-teroglucagon and neurotensin.  相似文献   
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CHANGE OF SEX     
DEWHURST CJ  GORDON RR 《Lancet》1963,2(7319):1213-1216
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Summary. Pregnancy-associated plasma protein-A (PAPP-A) and Schwangerschaftsprotein 1 (SP1) levels were measured in single serum samples from 60 patients admitted with vaginal bleeding in the first 14 weeks of pregnancy. When based on ultrasound diagnoses the prediction of non-viability (the predictive value) was 97% for SP1 and 84% for PAPP-A. Whereas the prediction of viability (above –2SD of the normal range) with SP1 was 88% the value with PAPP-A was only 57%; the poorer result obtained with PAPP-A probably reflects its longer half-life. Pregnancy outcome is not related to the duration of bleeding.  相似文献   
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