全文获取类型
收费全文 | 2395093篇 |
免费 | 169094篇 |
国内免费 | 4512篇 |
专业分类
耳鼻咽喉 | 35279篇 |
儿科学 | 75724篇 |
妇产科学 | 69872篇 |
基础医学 | 341922篇 |
口腔科学 | 70244篇 |
临床医学 | 203567篇 |
内科学 | 466233篇 |
皮肤病学 | 52293篇 |
神经病学 | 188630篇 |
特种医学 | 94130篇 |
外国民族医学 | 778篇 |
外科学 | 371282篇 |
综合类 | 53206篇 |
现状与发展 | 7篇 |
一般理论 | 720篇 |
预防医学 | 171883篇 |
眼科学 | 56415篇 |
药学 | 181656篇 |
6篇 | |
中国医学 | 4990篇 |
肿瘤学 | 129862篇 |
出版年
2018年 | 21781篇 |
2015年 | 21596篇 |
2014年 | 30053篇 |
2013年 | 46043篇 |
2012年 | 61460篇 |
2011年 | 65620篇 |
2010年 | 38977篇 |
2009年 | 37088篇 |
2008年 | 63400篇 |
2007年 | 68906篇 |
2006年 | 69855篇 |
2005年 | 68203篇 |
2004年 | 65958篇 |
2003年 | 63999篇 |
2002年 | 63175篇 |
2001年 | 109188篇 |
2000年 | 112364篇 |
1999年 | 95437篇 |
1998年 | 26409篇 |
1997年 | 23893篇 |
1996年 | 23538篇 |
1995年 | 22234篇 |
1994年 | 21062篇 |
1993年 | 19389篇 |
1992年 | 75812篇 |
1991年 | 74105篇 |
1990年 | 72975篇 |
1989年 | 71191篇 |
1988年 | 66383篇 |
1987年 | 65196篇 |
1986年 | 62300篇 |
1985年 | 59336篇 |
1984年 | 44463篇 |
1983年 | 38171篇 |
1982年 | 22846篇 |
1981年 | 20525篇 |
1979年 | 42442篇 |
1978年 | 30158篇 |
1977年 | 26094篇 |
1976年 | 24139篇 |
1975年 | 27006篇 |
1974年 | 31954篇 |
1973年 | 30937篇 |
1972年 | 29614篇 |
1971年 | 27597篇 |
1970年 | 25905篇 |
1969年 | 25018篇 |
1968年 | 23519篇 |
1967年 | 20832篇 |
1966年 | 19475篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
51.
Effects of poor glucose handling on arterial stiffness and left ventricular mass in normal children.
AIM: Cardiovascular risk factors can be present in children and young adults. We previously found abnormal microvascular function in children who had glucose intolerance and insulin resistance. The aim of the present study was to investigate whether they also have abnormalities in left ventricular mass (LVM) and arterial stiffness. METHODS: We measured heart dimensions and LVM using echocardiography, and arterial stiffness using pulse wave analysis in 23 children with good glucose handling (postfeeding glucose: 3.9 to 5 mmol/L) and 21 with poor glucose handling (7.7 to 11.4 mmol/L). RESULTS: The time to pulse reflection was slightly shorter in the poorer glucose handlers (mean+/-SD: 143+/-10 vs 153+/-20 ms, P=0.04), suggestive of increased arterial stiffness. Also in this group, there were significant relationships between intraventricular septal thickness, blood pressure and body mass index, but not in the normal glucose handlers. CONCLUSIONS: We have found that normal children who are in the lowest quintile of glucose tolerance in comparison with their peers are exhibiting the first signs of arterial stiffening. In addition, we have seen the beginnings of a relationship between blood pressure, body mass index and left ventricular enlargement in this group. While these changes may not yet be clinically significant, their emergence might be further evidence of early predisposition to cardiovascular disease. 相似文献
52.
G Garcia-Manero 《Leukemia》2003,17(11):2063-2064
53.
Setting goals to maintain hope. 总被引:3,自引:0,他引:3
54.
55.
56.
There is some evidence suggesting that Parkinson's disease (PD) patients exhibit lower body weight when compared to age-matched healthy subjects. Low body mass index (BMI) is correlated with low bone mineral density, both of which are major risk factors for hip fractures. Possible determinants of weight loss in PD patients include hyposmia, impaired hand-mouth coordination, difficulty chewing, dysphagia, intestinal hypomotility, depression, decreased reward processing of dopaminergic mesolimbic regions, nausea, and anorexia as the side effects of medication, and increased energy requirements due to muscular rigidity and involuntary movements. It is unclear whether PD patients in general, or only a subgroup of those affected, definitely show lower BMI in the advanced stages of the disease. We therefore recommend that the body weight of PD patients be monitored monthly as the disease progresses, and that a patient's nutrition should be supplemented with sufficient amounts of vitamin D and calcium to reduce the risk of hip fractures and strengthen bone density. Because meal times may coincide with unpredictable off periods associated with akinesia and impaired hand-mouth coordination, PD patients also need flexible food schedules that accommodate the associated symptoms of this disease. 相似文献
57.
Jonathan Halford Gandis Mazeika Susan Slifer Marcy Speer Ann M Saunders Warren J Strittmatter Joel C Morgenlander 《Movement disorders》2006,21(4):540-542
Ninety-seven inpatients with tardive dyskinesia (average AIMS score = 13), the majority of whom were schizophrenic, were studied. Forty patients were Caucasian, and 57 were African-American. The APOE genotypes of these patients were compared to previously published genotypes of controls and with previously published studies of APOE genotypes in patients with schizophrenia. There were no significant differences in APOE allele frequencies comparing the African-American tardive dyskinesia population and the African-American control groups. In contrast, significant (< 0.05) P values were obtained comparing the Caucasian tardive dyskinesia population to the Caucasian controls, when comparing allele frequencies and genotypic frequencies. This study suggests that Caucasians bearing an APOE2 allele are at increased risk of developing tardive dyskinesia, whereas African-Americans are not. APOE genotype-specific risks of both tardive dyskinesia and Alzheimer's disease that vary across populations could be due to recruitment of patients or controls or could be due to modifying effects of differing genetic or environmental backgrounds. The mechanism by which the APOE2 allele increases risk of tardive dyskinesia is not known. Further information about the mechanisms of increased risk of tardive dyskinesia could result in stratification of prescribing practices weighing the costs of medications against the relative risk of side effects. 相似文献
58.
59.
60.