全文获取类型
收费全文 | 1482945篇 |
免费 | 100132篇 |
国内免费 | 2059篇 |
专业分类
耳鼻咽喉 | 19955篇 |
儿科学 | 51629篇 |
妇产科学 | 38542篇 |
基础医学 | 204357篇 |
口腔科学 | 35397篇 |
临床医学 | 125517篇 |
内科学 | 295269篇 |
皮肤病学 | 28975篇 |
神经病学 | 118694篇 |
特种医学 | 61036篇 |
外国民族医学 | 660篇 |
外科学 | 231027篇 |
综合类 | 29878篇 |
现状与发展 | 1篇 |
一般理论 | 385篇 |
预防医学 | 115306篇 |
眼科学 | 31194篇 |
药学 | 105957篇 |
2篇 | |
中国医学 | 3084篇 |
肿瘤学 | 88271篇 |
出版年
2018年 | 35994篇 |
2017年 | 28190篇 |
2016年 | 32182篇 |
2015年 | 13623篇 |
2014年 | 18361篇 |
2013年 | 27588篇 |
2012年 | 43713篇 |
2011年 | 60296篇 |
2010年 | 42221篇 |
2009年 | 34258篇 |
2008年 | 58355篇 |
2007年 | 64326篇 |
2006年 | 41003篇 |
2005年 | 42125篇 |
2004年 | 42786篇 |
2003年 | 43211篇 |
2002年 | 40325篇 |
2001年 | 64649篇 |
2000年 | 67423篇 |
1999年 | 56861篇 |
1998年 | 15571篇 |
1997年 | 14238篇 |
1996年 | 14464篇 |
1995年 | 13794篇 |
1994年 | 13082篇 |
1993年 | 12040篇 |
1992年 | 44829篇 |
1991年 | 43773篇 |
1990年 | 42520篇 |
1989年 | 40373篇 |
1988年 | 37134篇 |
1987年 | 36489篇 |
1986年 | 33818篇 |
1985年 | 32474篇 |
1984年 | 24316篇 |
1983年 | 20448篇 |
1982年 | 11931篇 |
1981年 | 10806篇 |
1980年 | 9729篇 |
1979年 | 21510篇 |
1978年 | 14978篇 |
1977年 | 12645篇 |
1976年 | 11833篇 |
1975年 | 12681篇 |
1974年 | 14760篇 |
1973年 | 14174篇 |
1972年 | 12993篇 |
1971年 | 11771篇 |
1970年 | 11112篇 |
1969年 | 10087篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
991.
Lidong Zhang James E Littlejohn Yu Cui Xiaobo Cao Chander Peddaboina W Roy Smythe 《Molecular cancer》2010,9(1):110
Background
Bortezomib, a proteasome-specific inhibitor, has emerged as a promising cancer therapeutic agent. However, development of resistance to bortezomib may pose a challenge to effective anticancer therapy. Therefore, characterization of cellular mechanisms involved in bortezomib resistance and development of effective strategies to overcome this resistance represent important steps in the advancement of bortezomib-mediated cancer therapy. 相似文献992.
P Sundaresan R Yeghiaian-Alvandi V Gebski 《Journal of Medical Imaging and Radiation Oncology》2010,54(1):69-75
Palliative whole brain radiotherapy (WBRT) is often recommended in the management of multiple brain metastases. Allowing for WBRT waiting time, duration of the WBRT course and time to clinical response, it may take 6 weeks from the point of initial assessment for a benefit from WBRT to manifest. Patients who die within 6 weeks (‘early death’) may not benefit from WBRT and may instead experience a decline in quality of life. This study aimed to develop a prognostic index (PI) that identifies the subset of patients with lung cancer with multiple brain metastases who may not benefit from WBRT because of ‘early death’. The medical records of patients with lung cancer who had WBRT recommended for multiple brain metastases over a 10-year period were retrospectively reviewed. Patients were classified as either having died within 6 weeks or having lived beyond 6 weeks. Potential prognostic indicators were evaluated for correlation with ‘early death’. A PI was constructed by modelling the survival classification to determine the contribution of these factors towards shortened survival. Of the 275 patients recommended WBRT, 64 (23.22%) died within 6 weeks. The main prognostic factor predicting early death was Eastern Cooperative Oncology Group (ECOG) status >2. Patients with a high PI score (>13) were at higher risk of ‘early death’. Twenty-three per cent of patients died prior to benefit from WBRT. ECOG status was the most predictive for ‘early death’. Other factors may also contribute towards a poor outcome. With further refinement and validation, the PI could be a valuable clinical decision tool. 相似文献
993.
994.
995.
996.
997.
998.
Deborah P Jones Carlos A Camargo Frank E Speizer R Graham Barr 《The Journal of asthma》2007,44(4):291-295
The authors tested the hypothesis that short stature predicts adult-onset asthma independent of obesity among women in the Nurses' Health Study. Height, weight, and physician-diagnosed asthma were assessed with validated questionnaire items. Proportional hazard models adjusted separately for weight and body mass index. The rate of newly diagnosed asthma was 1.55 times greater in the shortest versus the tallest quintile after adjustment for weight (95% CI, 1.26-1.91). After adjustment for body mass index, the rate ratio was 1.16 (95% CI, 0.94-1.42). Short stature predicted adult-onset asthma in a large cohort of women, but this association was not independent of obesity. 相似文献
999.
Background
The fibromyalgia syndrome (FMS) is suggested to be a manifestation of depression or affective spectrum disorder. We measured the cognitive style of patients with FMS to assess personality styles in 44 patients with fibromyalgia syndrome (FMS) by comparing them with 43 patients with major depressive disorder (MDD) and 41 healthy controls (HC). 相似文献1000.