Melorheostosis: Presentation of a case followed up for 24 years

Summary The case of a woman affected by Melorheostosis of the left arm, who was followed for 24 years, is presented. After a brief review of the main clinico-radiological features and the most likely pathogenetic theory, the authors point out the slow but inexorable progression of the alterations and their localization, which is strictly limited to the dermatome supplied by a spinal nerve.

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Zusammenfassung Es wird über einen Fall von Melorheostose des linken Armes bei einer Frau berichtet, dessen Verlauf über 24 Jahre beobachtet wurde. Die Autoren weisen auf die hauptsächlichen klinischen und radiologischen Erscheinungen, die mögliche Pathogenese und auf das langsame unaufhaltsame Fortschreiten der Veränderung hin und stellen fest, daß auch in dem von ehnen beobachteten Fall die Lokalisation der Veränderung der Sklerotomanordnung entspricht.

     

Differenzialdiagnose und Therapieoptionen bei Tumoren der Konjunktiva

The diagnostic classification of most conjunctival tumors is based on case history, inspection, and examination with the slit lamp microscope. Further imaging procedures are rarely indicated when malignant processes are not circumscribed. Clinical classification then also includes palpation and echographic examination of regional lymph nodes. Pigmented and nonpigmented melanocytic nevi are the most frequent conjunctival tumors. An important practical biomicroscopic cardinal symptom of the most frequent nevi is the presence of epithelial pseudocysts. Essential in practice is the histopathological confirmation of the clinical diagnosis, e.g., distinguishing between nonpigmented melanomas and sebaceous gland carcinomas with a pagetoid growth pattern or squamous cell carcinomas. Depending on the course and findings, the following therapeutic measures can be indicated: cryotherapy, chemotherapy, radiotherapy, modified enucleation, orbital exenteration, or a combination of different methods.     

让我们为明天祝福

再没有多久，世界将随着历史的脚步进入二十一世纪，在这辞旧迎新的时刻即将到来之际，审视人类过去留下的足迹，展望未来世界的晨曦，我们的心情既是格外喜悦，又是异样沉重。数千年来，人类勤奋地开拓和孜孜不倦地创造，使得我们这个世界愈来愈多姿多彩，到处充满了活力，人们的物质享受与科技进步齐头并进，人类几十个世纪的梦想正在逐渐实现。     

Problem der Mehrlingsschwangerschaft nach assistierter Reproduktion

In western countries, techniques of assisted reproduction are responsible for the considerable increase in the rate of multiple pregnancies and deliveries in the last two decades. These pregnancies and deliveries are associated with high risks for babies, pregnant women and mothers. Obstetricians and neonatologists are often faced with the problem of extremely premature delivery and growth retardation in such cases. Limiting the number of preembryos for transfer would obviously seem to be the most important strategy for minimizing the multiple pregnancy rate. The specific situation in this area in Europe, especially in Germany, is shown. Experience so far with elective single embryo transfer is described.