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PIER-CARL MONTECUCCHI ANNA MARIA LAZZARINI LUIGI BARBIERI FIORENZO STIRPE MARCO SORIA DOUGLAS LAPPI 《Chemical biology & drug design》1989,33(4):263-267
The N-terminal portion of some type 1 ribosome-inactivating proteins (RIPs) isolated from the seeds of Gelonium multifiorum, Momordica charantia, Bryonia dioica, Saponaria oficinalis and from the leaves of Saponaria oficinalis are reported in the present paper. Their relationship with other RIPS is discussed. 相似文献
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FABRIZIO D'ASCENZO M.D. FRANCESCO COLOMBO M.D. UMBERTO BARBERO M.D. CLAUDIO MORETTI M.D. PIERLUIGI OMEDÈ M.D. MATTHEW J. REED M.D. GIUSEPPE TARANTINI M.D. GIACOMO FRATI M.D. JAMES J. DI NICOLANTONIO PharmD. GIUSEPPE BIONDI ZOCCAI M.D. FIORENZO GAITA M.D. 《Journal of interventional cardiology》2014,27(3):233-241
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SERENA BENINATI M.D. JACOPO PERVERSI M.D. MARCO SCAGLIONE M.D. ANTONIO MONTEFUSCO M.D. FIORENZO GAITA M.D. 《Pacing and clinical electrophysiology : PACE》2011,34(4):e33-e37
Radiofrequency catheter ablation is now the first line treatment for atrioventricular nodal reentrant tachycardia. The success rate is high with a low incidence of complications. However, a possible proarrhythmic effect of radiofrequency energy has been rarely reported and no study has demonstrated a direct correlation between the anatomic site of the radiofrequency application and the origin of a new post‐ablation arrhythmia. We present a case of a focal atrial tachycardia that occurred after slow pathway radiofrequency catheter ablation for atrial nodal reentrant tachycardia and originating close to the previous ablation site. This tachycardia was successfully treated with a second ablation session. (PACE 2011; 34:e33–e37) 相似文献
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MATTEO ANSELMINO M.D. Ph.D. ALESSANDRO BLANDINO M.D. SERENA BENINATI M.D. CHIARA ROVERA M.D. CARLO BOFFANO M.D. MARCO BELLETTI M.D. DOMENICO CAPONI M.D. MARCO SCAGLIONE M.D. FEDERICO CESARANI M.D. FIORENZO GAITA M.D. 《Journal of cardiovascular electrophysiology》2011,22(1):1-7
LA and PV Anatomy in Patients With AF. Introduction: Although transcatheter atrial fibrillation (AF) ablation requires accurate anatomic knowledge, pulmonary vein (PV) anatomy has not been fully investigated. Aim of this study is to describe left atrium (LA) and PV anatomy by magnetic resonance angiography (MRA) in a large cohort of patients with AF. Methods: MRA was performed in 473 patients preceding transcatheter AF ablation (paroxysmal 60.9%; persistent 39.1%). The Venice Chart classification was used to classify PV branching patterns. Results: About 40% of the patients presented typical PV branching pattern (2 left and 2 right PVs). A representative number of patients presented a common left trunk (19.9% and 11.0% short and long, respectively). A right middle PV was described in 12.5% and 2 right middle PVs in 1.5% patients. The remaining patients presented other complex, previously unclassified patterns: 6.3% presented an accessory PV originating from LA areas not describable as right or “upper” and 8.7% a common left trunk plus right middle PV. Diameters and circumference of each PV, LA, and LA appendage volumes resulted larger in patients presenting persistent compared to paroxysmal AF (P < 0.001). Conclusion: This study highlights that “typical” PV branching pattern is not a common finding. That 25.6% of the patients present at least 1 accessory PV needs to be kept in careful consideration when planning and performing transcatheter AF ablation. In addition, not only LA volume, but also each PV ostia and LA appendage are significantly enlarged in patients with persistent compared to paroxysmal AF. (J Cardiovasc Electrophysiol, Vol. 22, pp. 1‐7, January 2011) 相似文献
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A Meta‐Analysis of Sex‐Related Differences in Outcomes After Primary Percutaneous Intervention for ST‐Segment Elevation Myocardial Infarction
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FEDERICO CONROTTO M.D. FABRIZIO D'ASCENZO M.D. KARIN H HUMPHRIES D.Sc. JOHN G WEBB M.D. PAOLO SCACCIATELLA M.D. COSTANZA GRASSO M.D. MAURIZIO D'AMICO M.D. GIUSEPPE BIONDI‐ZOCCAI M.D. FIORENZO GAITA M.D. SEBASTIANO MARRA M.D. 《Journal of interventional cardiology》2015,28(2):132-140
Introduction
The increasing use of primary percutaneous coronary intervention (pPCI) has improved clinical outcome in ST‐segment elevation myocardial infarction (STEMI) patients, but the impact of sex on early and mid‐term outcomes remains to be defined.Methods
Medline, Cochrane Library, Biomed Central, and Google Scholar were searched for articles describing differences in baseline, periprocedural, and midterm outcomes after pPCI, by sex. The primary end point was all‐cause mortality at early and mid‐term follow‐up. Secondary endpoints included in‐hospital bleeding and stroke.Results
Sixteen studies were included. Women were older, had more frequent hypertension, diabetes mellitus, and hypercholesterolemia, as well as longer ischemia time and more shock at presentation. Men were more likely to have had a previous myocardial infarction. Female sex emerged as independently associated to early mortality (OR 1.1; 95%CI, 1.02–1.18) but not to mid‐term mortality (OR, 1.01; 95%CI, 0.99–1.03). The pooled analysis showed a significantly higher risk of in hospital stroke (OR, 1.69; 95%CI, 1.11–2.56) and major bleeding (OR, 2.04; 95%CI, 1.51–2.77) in women.Conclusions
As compared to men, women undergoing pPCI have more bleedings and strokes, and a worse early, but not mid‐term mortality. These findings may allow a better risk stratification of pPCI patients.18.
HIN WING YEUNG WAI WAN LI ZHANG FENG LUIGI BARBIERI FIORENZO STIRPE 《Chemical biology & drug design》1988,31(3):265-268
The abortifacient proteins trichosanthin, α-momorcharin and β-momorcharin at nM concentrations inhibit cell-free protein synthesis. The momorcharins and the ribosome-inactivating proteins isolated from Momordica charantia seeds cross-react with the respective antisera. The ribosome-inactivating proteins saporins, pokeweed antiviral protein (PAP) and, to a lesser extent, gelonin have abortifacient activity on pregnant mice. 相似文献
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