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Dr. Theodor Wiznitzer MD FACS Ruben Orda MD MSc Jaim B. Bawnik MD Jose J. Bubis MD 《Digestive diseases and sciences》1976,21(6):459-464
The effect of chlorophylla on experimental acute pancreatitis in guinea pigs was investigated. Pancreatitis was induced by intrapancreatic infiltration of a sodium taurocholate solution. Animals treated with intrapancreatic or intraperitoneal injections of chlorophylla showed higher survival rate than untreated controls.Supported in part by a Research Grant from the Chief Scientist, The Ministry of Health, Israel. 相似文献
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I. G. M. Cleator MB ChBEd FRCSE FRCS FRCS J. L. Stoller MB FRCSE FRCS P. N. Nunn MB FRCS I. B. Holubitsky MD FACS FRCS F. R. C. Johnstone MB MSc FRCSE FACS R. C. Harrison MD MS FRCS 《Digestive diseases and sciences》1973,18(4):301-310
The purpose of this study was to assess whether consideration of age and body weight measurements improved discrimination between normal subjects and duodenal ulcer subjects using the maximal acid output test. Seventy-seven male volunteers were the normal group, and 155 patients with surgically proven duodenal ulcers were the ulcer group. We found that the ratio of maximal acid output to actual weight gave the best discrimination between the two groups. Using this ratio, there were 45 hypersecretors in the ulcer group, and only 1 false-positive among the normal subjects. A graphic method is described which employs the ratio of acid to weight and can correctly classify two-thirds of the ulcer group. The disadvantage of this method, however, is that one-third of the control group in our series were misclassified as hypersecretors; therefore, the clinician must consider history and barium meal findings as well as this evaluation of the subject.Deceased. 相似文献
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Barrett's esophagus: Pathogenesis,epidemiology, functional abnormalities,malignant degeneration,and surgical management 总被引:4,自引:0,他引:4
Barrett's esophagus (i.e. columnar epithelial metaplasia in the distal esophagus) is an acquired condition that in most patients results from chronic gastroesophageal reflux. It is a disorder of the white male in the Western world with a prevalence of about 1/400 population. Due to the decreased sensitivity of the columnar epithelium to symptoms, Barrett's esophagus remains undiagnosed in the majority of patients. Gastroesophageal reflux disease in patients with Barrett's esophagus has a more severe character and is more frequently associated with complications as compared with reflux patients without columnar mucosa. This appears to be due to a combination of a mechanically defective lower esophageal sphincter, inefficient esophageal clearance function, and gastric acid hypersecretion. Excessive reflux of alkaline duodenal contents may be responsible for the development of complications (i.e., stricture, ulcer, and dysplasia). Therapy of benign Barrett's esophagus is directed towards treatment of the underlying reflux disease. Barrett's esophagus is associated with a 30- to 125-fold increased risk for adenocarcinoma of the esophagus. The reasons for the dramatic rise in the incidence of esophageal adenocarcinoma, which occurred during the past years, are unknown. High grade dysplasia in a patient with columnar mucosa is an ominous sign for malignant degeneration. Whether an esophagectomy should be performed in patients with high grade dysplasia remains controversial. Complete resection of the tumor and its lymphatic drainage is the procedure of choice in all patients with a resectable carcinoma who are fit for surgery. In patients with tumors located in the distal esophagus, this can be achieved by a transhiatal en-bloc esophagectomy and proximal gastrectomy. Early adenocarcinoma can be cured by this approach. The value of multimodality therapy in patients with advanced tumors needs to be shown in randomized prospective trials. 相似文献
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Rapid,high‐fluence multi‐pass q‐switched laser treatment of tattoos with a transparent perfluorodecalin‐infused patch: A pilot study
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Brian S. Biesman MD FACS Michael P. O'Neil PhD Cara Costner RN FNP 《Lasers in surgery and medicine》2015,47(8):613-618