全文获取类型
收费全文 | 2121312篇 |
免费 | 155828篇 |
国内免费 | 6235篇 |
专业分类
耳鼻咽喉 | 27920篇 |
儿科学 | 68599篇 |
妇产科学 | 59097篇 |
基础医学 | 308864篇 |
口腔科学 | 58731篇 |
临床医学 | 195933篇 |
内科学 | 413475篇 |
皮肤病学 | 42948篇 |
神经病学 | 175645篇 |
特种医学 | 80304篇 |
外国民族医学 | 678篇 |
外科学 | 307386篇 |
综合类 | 44970篇 |
现状与发展 | 2篇 |
一般理论 | 773篇 |
预防医学 | 175664篇 |
眼科学 | 47125篇 |
药学 | 153573篇 |
6篇 | |
中国医学 | 4681篇 |
肿瘤学 | 117001篇 |
出版年
2019年 | 17701篇 |
2018年 | 24595篇 |
2017年 | 18952篇 |
2016年 | 20593篇 |
2015年 | 23443篇 |
2014年 | 32656篇 |
2013年 | 49999篇 |
2012年 | 68685篇 |
2011年 | 72872篇 |
2010年 | 42692篇 |
2009年 | 40060篇 |
2008年 | 67323篇 |
2007年 | 71182篇 |
2006年 | 71211篇 |
2005年 | 69025篇 |
2004年 | 65440篇 |
2003年 | 62702篇 |
2002年 | 61110篇 |
2001年 | 93496篇 |
2000年 | 96102篇 |
1999年 | 81352篇 |
1998年 | 23454篇 |
1997年 | 21256篇 |
1996年 | 21028篇 |
1995年 | 19756篇 |
1994年 | 18603篇 |
1993年 | 17539篇 |
1992年 | 64448篇 |
1991年 | 62676篇 |
1990年 | 60931篇 |
1989年 | 58151篇 |
1988年 | 53954篇 |
1987年 | 52737篇 |
1986年 | 50314篇 |
1985年 | 48159篇 |
1984年 | 36322篇 |
1983年 | 30933篇 |
1982年 | 18640篇 |
1979年 | 33113篇 |
1978年 | 23405篇 |
1977年 | 19451篇 |
1976年 | 18820篇 |
1975年 | 19752篇 |
1974年 | 23920篇 |
1973年 | 23233篇 |
1972年 | 21696篇 |
1971年 | 20181篇 |
1970年 | 18894篇 |
1969年 | 17456篇 |
1968年 | 16709篇 |
排序方式: 共有10000条查询结果,搜索用时 31 毫秒
991.
992.
Irwin L. Flink 《Brain structure & function》2002,205(3):235-244
993.
Acta Endoscopica - L’hémorragie iatrogène en endoscopie digestive reste pour l’essentiel l’apanage des techniques de résection tumorale et de la... 相似文献
994.
995.
M. Wensing A. H. Penninks† S. L. Hefle‡ J. H. Akkerdaas§ R. van Ree§ S. J. Koppelman† C. A. F. M. Bruijnzeel-Koomen A. C. Knulst 《Clinical and experimental allergy》2002,32(12):1757-1762
BACKGROUND: The risk for allergic reactions depends on the sensitivity of individuals and the quantities of offending food ingested. The sensitivity varies among allergic individuals, as does the threshold dose of a food allergen capable of inducing an allergic reaction. OBJECTIVE: This study aimed at determining the distribution of minimum provoking doses of hazelnut in a hazelnut-allergic population. METHODS: Thirty-one patients with a history of hazelnut-related allergic symptoms, a positive skin prick test to hazelnut and/or an elevated specific IgE level, were included. Double-blind, placebo-controlled food challenges (DBPCFC) were performed with seven increasing doses of dried hazelnut (1 mg to 1 g hazelnut protein) randomly interspersed with seven placebo doses. RESULTS: Twenty-nine patients had a positive challenge. Itching of the oral cavity and/or lips was the first symptom in all cases. Additional gastrointestinal symptoms were reported in five patients and difficulty in swallowing in one patient. Lip swelling was observed in two patients, followed by generalized urticaria in one of these. Threshold doses for eliciting subjective reactions varied from a dose of 1 mg up to 100 mg hazelnut protein (equivalent to 6.4-640 mg hazelnut meal). Extrapolation of the dose-response curve showed that 50% of our hazelnut-allergic population will suffer from an allergic reaction after ingestion of 6 mg (95% CI, 2-11 mg) of hazelnut protein. Objective symptoms were observed in two patients after 1 and 1,000 mg, respectively. CONCLUSION: DBPCFCs demonstrated threshold doses in half of the hazelnut-allergic patients similar to doses previously described to be hidden in consumer products. This stresses the need for careful labelling and strategies to prevent and detect contamination of food products with hazelnut residues. 相似文献
996.
Effects of laundry detergents on Dermatophagoides farinae, Dermatophagoides pteronyssinus, and Euroglyphus maynei. 总被引:2,自引:0,他引:2
DiAnn L Vyszenski-Moher Larry G Arlian Jacquelines S Neal 《Annals of allergy, asthma & immunology》2002,88(6):578-583
BACKGROUND: House-dust mites in clothing and bedding are the source of major allergens. Based on studies of Dermatophagoides pteronyssinus only, weekly washing in hot water is recommended to kill dust mites and remove allergens from clothing and bedding. However, in the United States, washing is most often done in warm or cold water, and other mite species are involved. OBJECTIVE: The purpose of this study was to investigate the lethal effects of various temperatures of hot water alone and hot, warm, and cold water containing detergents and chlorine bleach on Dermatophagoidesfarinae, D. pteronyssinus, and Euroglyphus maynei. METHODS: Mites were soaked in test solutions at various temperatures and for various lengths of time, allowed time to recover, and then analyzed for survival. RESULTS: D. farinae was the most temperature-sensitive and chlorine bleach-sensitive of the three species. In 50 degrees C water alone, 100% mortality for D. farinae was obtained in 10 minutes, whereas most D. pteronyssinus and E. maynei survived. However, 53 degrees C-soaks for 12 and 5 minutes were needed to kill all D. pteronyssinus and E. maynei, respectively. Laundry detergents at their recommended and doubled concentrations and chlorine bleach generally increased mite mortalities over water alone for the three species. Soaking for 4 hours in warm water containing various detergents alone induced mortalities of 19 to 50%, 2 to 35%, and 14 to 46% for D. farinae, D. pteronyssinus, and E. maynei, respectively. CONCLUSIONS: Washing bed linens weekly in warm water with a 4-hour presoak containing most detergents and bleach will kill most D. farinae and, depending on the detergent brand, moderate numbers of D. pteronyssinus. Four-hour soaks in warm water containing the recommended concentrations of various detergents alone also kills moderate numbers of D. farinae, D. pteronyssinus, and E. maynei. Therefore, the cumulative effect of weekly washing with long presoaks should significantly reduce mite levels over time in bed linens, particularly when mattresses and pillows are encased to prevent reinfestation. 相似文献
997.
D. Lothschütz M. Jennewein S. Pahl H.F. Lausberg A. Eichler W. Mutschler R.G. Hanselmann M. Oberringer 《Inflammation research》2002,51(8):416-422
OBJECTIVE AND DESIGN: Inflammatory and tumorous bronchi were screened in order to obtain new tumor relevant cytogenetic parameters. MATERIAL OR SUBJECTS: Bronchial cells of 32 patients were cultivated by standard cell culture procedures. METHODS: Tetraploidy and aneuploidy was determined by enumeration of chromosome 7 and 8 versus the number of centrosomes. The resulting data were correlated with histopathological data. RESULTS: Tetra- and aneuploidy of epithelial cells were detectable in 76% of tumor cell cultures, 75% of high grade inflammatory tissues and 40% of non- and low grade-inflammatory tissues. Additionally, we observed centrosome hyper-amplification and multipolar mitoses not only in the tumor but also in the early stages of inflammation. CONCLUSION: Inflammatory bronchi already show tumor-specific features and may consequently represent the preliminary genetic stage of cancer development in bronchi. 相似文献
998.
T. Berghmans F. Crokaert J. Sculier 《European journal of clinical microbiology & infectious diseases》2002,21(9):676-678
Vibrio cholerae was isolated from the blood cultures of a neutropenic patient treated with chemotherapy for non-small-cell lung cancer. Attempts
to isolate Vibrio spp. from a rectal swab and stool were unsuccessful. Piperacillin/tazobactam treatment resulted in eradication of the microorganism
from the patient's blood. Although Vibrio spp. have occasionally been the source of infection in immunocompromised patients, this report describes the first case of
non-0:1 Vibrio cholerae bacteremia in a neutropenic patient with a solid tumour.
Electronic Publication 相似文献
999.
A. Giacometti O. Cirioni G. Greganti A. Fineo R. Ghiselli M. Del Prete F. Mocchegiani B. Fileni F. Caselli E. Petrelli V. Saba G. Scalise 《European journal of clinical microbiology & infectious diseases》2002,21(7):553-556
The in vitro activities of povidone iodine, potassium peroxymonosulfate, and dimethyldidecylammonium chloride were investigated
against 379 nosocomial isolates of Staphylococcus aureus and Pseudomonas aeruginosa responsible for surgical wound infections in patients operated on between July 1995 and June 2001. Overall, the isolates
were inhibited by the antiseptics at concentrations below those used routinely. In spite of increasing resistance to the various
antibiotics used to treat surgical wound infections, no significant variation in the susceptibility to antiseptics was demonstrated
during this 6-year study.
Electronic Publication 相似文献
1000.