全文获取类型
收费全文 | 3758篇 |
免费 | 184篇 |
国内免费 | 33篇 |
专业分类
耳鼻咽喉 | 85篇 |
儿科学 | 147篇 |
妇产科学 | 134篇 |
基础医学 | 262篇 |
口腔科学 | 152篇 |
临床医学 | 344篇 |
内科学 | 919篇 |
皮肤病学 | 169篇 |
神经病学 | 287篇 |
特种医学 | 143篇 |
外科学 | 824篇 |
综合类 | 55篇 |
预防医学 | 76篇 |
眼科学 | 125篇 |
药学 | 132篇 |
中国医学 | 8篇 |
肿瘤学 | 113篇 |
出版年
2023年 | 32篇 |
2022年 | 63篇 |
2021年 | 90篇 |
2020年 | 77篇 |
2019年 | 80篇 |
2018年 | 124篇 |
2017年 | 100篇 |
2016年 | 143篇 |
2015年 | 146篇 |
2014年 | 153篇 |
2013年 | 227篇 |
2012年 | 291篇 |
2011年 | 280篇 |
2010年 | 168篇 |
2009年 | 126篇 |
2008年 | 261篇 |
2007年 | 268篇 |
2006年 | 249篇 |
2005年 | 223篇 |
2004年 | 200篇 |
2003年 | 166篇 |
2002年 | 152篇 |
2001年 | 80篇 |
2000年 | 46篇 |
1999年 | 46篇 |
1998年 | 16篇 |
1997年 | 10篇 |
1996年 | 9篇 |
1995年 | 5篇 |
1994年 | 9篇 |
1993年 | 7篇 |
1992年 | 15篇 |
1991年 | 9篇 |
1990年 | 8篇 |
1989年 | 8篇 |
1988年 | 10篇 |
1987年 | 9篇 |
1986年 | 6篇 |
1985年 | 7篇 |
1984年 | 6篇 |
1979年 | 5篇 |
1976年 | 2篇 |
1974年 | 3篇 |
1972年 | 2篇 |
1971年 | 2篇 |
1970年 | 4篇 |
1969年 | 3篇 |
1967年 | 8篇 |
1966年 | 4篇 |
1909年 | 2篇 |
排序方式: 共有3975条查询结果,搜索用时 15 毫秒
21.
22.
Dr. med. R. Kaya 《Virchows Archiv : an international journal of pathology》1907,189(3):466-512
Ohne ZusammenfassungHierzu drei Textabbildungen und Taf. XIV. 相似文献
23.
Blythe A. Layton Devrim Kaya Christine Kelly Kenneth J. Williamson Dana Alegre Silke M. Bachhuber Peter G. Banwarth Jeffrey W. Bethel Katherine Carter Benjamin D. Dalziel Mark Dasenko Matthew Geniza Andrea George Anne-Marie Girard Roy Haggerty Kathryn A. Higley Denise M. Hynes Jane Lubchenco Katherine R. McLaughlin F. Javier Nieto Aslan Noakes Matthew Peterson Adriana D. Piemonti Justin L. Sanders Brett M. Tyler Tyler S. Radniecki 《Environmental health perspectives》2022,130(6)
Background: Positive correlations have been reported between wastewater SARS-CoV-2 concentrations and a community’s burden of infection, disease or both. However, previous studies mostly compared wastewater to clinical case counts or nonrepresentative convenience samples, limiting their quantitative potential.Objectives: This study examined whether wastewater SARS-CoV-2 concentrations could provide better estimations for SARS-CoV-2 community prevalence than reported cases of COVID-19. In addition, this study tested whether wastewater-based epidemiology methods could identify neighborhood-level COVID-19 hotspots and SARS-CoV-2 variants.Methods: Community SARS-CoV-2 prevalence was estimated from eight randomized door-to-door nasal swab sampling events in six Oregon communities of disparate size, location, and demography over a 10-month period. Simultaneously, wastewater SARS-CoV-2 concentrations were quantified at each community’s wastewater treatment plant and from 22 Newport, Oregon, neighborhoods. SARS-CoV-2 RNA was sequenced from all positive wastewater and nasal swab samples. Clinically reported case counts were obtained from the Oregon Health Authority.Results: Estimated community SARS-CoV-2 prevalence ranged from 8 to 1,687/10,000 persons. Community wastewater SARS-CoV-2 concentrations ranged from 2.9 to gene copies per liter. Wastewater SARS-CoV-2 concentrations were more highly correlated (Pearson’s ; ) with community prevalence than were clinically reported cases of COVID-19 (Pearson’s ; ). Monte Carlo simulations indicated that wastewater SARS-CoV-2 concentrations were significantly better than clinically reported cases at estimating prevalence (). In addition, wastewater analyses determined neighborhood-level COVID-19 hot spots and identified SARS-CoV-2 variants (B.1 and B.1.399) at the neighborhood and city scales.Discussion: The greater reliability of wastewater SARS-CoV-2 concentrations over clinically reported case counts was likely due to systematic biases that affect reported case counts, including variations in access to testing and underreporting of asymptomatic cases. With these advantages, combined with scalability and low costs, wastewater-based epidemiology can be a key component in public health surveillance of COVID-19 and other communicable infections. https://doi.org/10.1289/ EHP10289相似文献
24.
Bahadir Kirilmaz Serkan Saygi Hasan Gungor Ugur Onse Turk Emin Alioglu Serdar Akyuz Fatih Asgun Istemihan Tengiz Ertugrul Ercan 《老年心脏病学杂志》2012,9(3):237-242
Objectives Although development of new treatment modalities limited digoxin usage, digoxin intoxication is still an important issue which could be easily overlooked. In this report we analyzed a case series definitively diagnosed as digoxin intoxication in the modern era. Methods We analyzed 71 patients hospitalized with digoxin intoxication confirmed by history, complaints, clinical and electrocardiograph (ECG) findings, and serum digoxin levels > 2.0 ng/mL, during a five year period. The demographic and clinical data, indications for digoxin use, digoxin dosage, concurrent medications, laboratory data, hospital monitoring, and ECG findings were obtained from all patients. Results Thirty-eight of 71 patients (53.5%) had symptoms of heart failure during admission or later. Sixty-four percent of patients were older than 75 years. The percentage of females was 67%. Atrial fibrillation, hypertension and gastrointestinal complaints were more frequent in the females (64% in females, 30% in males, P = 0.007; 81% in female, 52% in males, P = 0.01; 50% in female, 17.3% in males, P = 0.008, respectively). The mortality rate during the hospital course was 7%. Conclusion This report demonstrated the reduced mortality rates in patients with digoxin intoxication over the study period. Gastrointestinal complaints are the most common symptoms in this population. 相似文献
25.
26.
M. Erkoçoğlu A. Kaya D. Azkur Ş. Özyer C. Özcan M. Beşli E. Civelek C.N. Kocabaş 《Allergologia et immunopathologia》2013,41(3):169-175
BackgroundEmerging evidence suggests that sex steroid hormones may influence respiratory symptoms. The existing literature about the role of oral contraceptive pill (OCP) on respiratory disease is scarce and conflicting especially during the adolescent period. In this study, we aimed to investigate the effect of OCPs on current wheezing among adolescents and young adults.MethodsA questionnaire was administered face-to-face to adolescents and young women by a physician. The questionnaire included ISAAC survey-comprised questions on ever wheezing, current wheezing, allergic diseases, smoking history (active or passive), and family history of allergic diseases and questions on OCP usage status. The effect of OCPs on wheezing was evaluated by logistic regression analysis.ResultsA total of 487 subjects aged between 11.3 and 25.6 years participated in the study and 196 (40.2%) reported that they had used OCPs. 7.4% of the participants had physician-diagnosed asthma and 10.3% of them were active smokers. It was detected that OCPs were associated with increased risk for current wheezing (odds ratio, 2.36; 95% CI, 1.25–4.47 adjusted for asthma and current smoker) and this risk was related with the usage during the past year.ConclusionYoung women taking oral contraceptives had a higher rate of current wheezing, suggesting that sex steroids may be of importance for respiratory health. 相似文献
27.
28.
29.
30.
Seda Tasdemir Hakan Parlakpinar Nigar Vardi Emin Kaya Ahmet Acet 《Fundamental & clinical pharmacology》2013,27(3):299-307
Inflammatory bowel disease has been linked to elevated T cells. Excessive production of reactive oxygen species and apoptosis are known to be accompanied by intestinal inflammation. This study was designed to investigate the effects of melatonin (MEL) and erythropoietin (EPO), which is a known anti‐inflammatory and antiapoptotic agent, in dinitrobenzene sulfonic acid (DNBS)–induced colitis in pinealectomized (Px) rats. In microscopically results, epithelial and goblet cell loss, absence of crypts, and increased colonic caspase‐3 activity were observed in the DNBS group. Also, in flow cytometric analysis, the percentage of CD4+ T cells was highest in the DNBS group. Treatment with MEL or EPO had a curative effect on DNBS‐induced colitis. The MEL + EPO groups showed significantly greater improvement when compared with the other treatment groups. Our results indicate that the combination of EPO and MEL may exert more beneficial effects than either agent used alone. 相似文献