全文获取类型
收费全文 | 513篇 |
免费 | 46篇 |
国内免费 | 6篇 |
专业分类
耳鼻咽喉 | 1篇 |
儿科学 | 15篇 |
妇产科学 | 7篇 |
基础医学 | 34篇 |
口腔科学 | 27篇 |
临床医学 | 49篇 |
内科学 | 105篇 |
皮肤病学 | 8篇 |
神经病学 | 21篇 |
特种医学 | 100篇 |
外科学 | 47篇 |
综合类 | 66篇 |
预防医学 | 32篇 |
眼科学 | 6篇 |
药学 | 28篇 |
中国医学 | 4篇 |
肿瘤学 | 15篇 |
出版年
2023年 | 2篇 |
2022年 | 5篇 |
2021年 | 9篇 |
2020年 | 7篇 |
2019年 | 7篇 |
2018年 | 16篇 |
2017年 | 12篇 |
2016年 | 11篇 |
2015年 | 16篇 |
2014年 | 18篇 |
2013年 | 28篇 |
2012年 | 21篇 |
2011年 | 21篇 |
2010年 | 42篇 |
2009年 | 29篇 |
2008年 | 19篇 |
2007年 | 21篇 |
2006年 | 23篇 |
2005年 | 13篇 |
2004年 | 8篇 |
2003年 | 11篇 |
2002年 | 5篇 |
2001年 | 5篇 |
2000年 | 12篇 |
1999年 | 7篇 |
1998年 | 15篇 |
1997年 | 17篇 |
1996年 | 17篇 |
1995年 | 15篇 |
1994年 | 15篇 |
1993年 | 16篇 |
1992年 | 2篇 |
1991年 | 3篇 |
1990年 | 4篇 |
1989年 | 10篇 |
1988年 | 8篇 |
1987年 | 7篇 |
1986年 | 6篇 |
1985年 | 13篇 |
1984年 | 5篇 |
1983年 | 5篇 |
1982年 | 2篇 |
1981年 | 8篇 |
1980年 | 4篇 |
1979年 | 3篇 |
1978年 | 3篇 |
1977年 | 5篇 |
1976年 | 5篇 |
1975年 | 7篇 |
1968年 | 1篇 |
排序方式: 共有565条查询结果,搜索用时 0 毫秒
51.
52.
U. Rüb H. Heinsen† E. R. Brunt‡ B. Landwehrmeyer§ W. FA Den Dunnen¶ K. Gierga T. Deller 《Neuropathology and applied neurobiology》2009,35(1):4-15
Recent progress in oculomotor research has enabled new insights into the functional neuroanatomy of the human premotor oculomotor brainstem network. In the present review, we provide an overview of its functional neuroanatomy and summarize the broad range of oculomotor dysfunctions that may occur in Huntington's disease (HD) patients. Although some of these oculomotor symptoms point to an involvement of the premotor oculomotor brainstem network in HD, no systematic analysis of this functional system has yet been performed in brains of HD patients. Therefore, its exact contribution to oculomotor symptoms in HD remains unclear. A possible strategy to clarify this issue is the use of unconventional 100-µm-thick serial tissue sections stained for Nissl substance and lipofuscin pigment (Nissl-pigment stain according to Braak). This technique makes it possible to identify the known nuclei of the premotor oculomotor brainstem network and to study their possible involvement in the neurodegenerative process. Studies applying this morphological approach and using the current knowledge regarding the functional neuroanatomy of this human premotor oculomotor brainstem network will help to elucidate the anatomical basis of the large spectrum of oculomotor dysfunctions that are observed in HD patients. This knowledge may aid clinicians in the diagnosis and monitoring of the disease. 相似文献
53.
54.
55.
A method of automatic exposure termination (AET) for xeromammography has been devised, significantly reducing the rate of repeat exposures due to poor choice of manual exposure factors. AET images are of good quality and are reliably produced. The concept of AET is based on the existence of an optimal transmitted exposure to the selenium plate, which is easily determined experimentally. In routine clinical xeromammography, a repeat rate of 20% was eliminated by the use of AET. 相似文献
56.
F. A. El-Yazbi M. A. Korany Mona Bedair 《Journal of clinical pharmacy and therapeutics》1985,10(4):373-377
A simple and rapid colorimetric method for the determination of imipramine hydrochloride and desipramine hydrochloride in their tablet formulations and in biological fluids is presented. The method is based on the reaction of these drugs with 3-methyl-2-benzothiazolone hydrazone in the presence of ferric chloride, with direct measurement at 635 nm. Cyclohexane was used to extract these drugs from serum and urine, at basic pH, by a single manual extraction. The method can detect 0.5 μg/ml of each drug. The main advantages of this method are its simplicity and high sensitivity. 相似文献
57.
Focused US system for MR imaging-guided tumor ablation 总被引:8,自引:0,他引:8
Cline HE; Hynynen K; Watkins RD; Adams WJ; Schenck JF; Ettinger RH; Freund WR; Vetro JP; Jolesz FA 《Radiology》1995,194(3):731
58.
59.
Purpose: This study examines 90 patients presenting with choroidal or ciliochoroidal melanoma to the Professorial Unit at the Sydney Eye Hospital. The indications for treatment, and the outcome for the eye and vision are presented together with an account of mortality and the incidence of metastases. Methods: A retrospective analysis of 90 choroidal melanoma patients managed by one surgeon over a 16-year period was undertaken. Initial findings, investigations performed, incidence of metastatic disease, treatment received and complication rates and mortality, where applicable, were recorded. Results: The group was followed for an average of 64 months (range, 5–172 months). Primary treatment was with either Iodine125 (1251) brachytherapy, local excision or enucleation. Radiation retinopathy was prominent in 1251 cases resulting in poor visual acuity when the tumour resided in the posterior pole. Local excision even of large tumours was effective particularly if peripheral. Overall metastatic disease was seen in 11% with 5-year survival rates for the metastatic group being 10%. Prognosis after diagnosis of metastases was poor. Conclusions: Specific therapy for choroidal melanoma must relate to the size and location of the tumour at the time of diagnosis. Visual outcome relates directly to the proximity of the tumour to the optic nerve and fovea. Metastatic disease latency can be prolonged; therefore caution about prognosis is required long after therapy is given. The 5-year survival is encouraging with all forms of therapy. However, as the natural history of ocular melanoma is variable and not fully delineated it is important to monitor the effects of conservative therapy. Further long-term survival data is required to distinguish whether one form of treatment is advantageous over the others, although case-control studies are difficult for ethical and practical reasons. In this regard the Collaborative Ocular Melanoma Study (COMS) will provide further evidence for the safety and efficacy of conservative therapy with brachytherapy compared to enucleation. 相似文献
60.