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排序方式: 共有7647条查询结果,搜索用时 15 毫秒
101.
Michael J Curtis Richard A Bond Domenico Spina Amrita Ahluwalia Stephen P A Alexander Mark A Giembycz Annette Gilchrist Daniel Hoyer Paul A Insel Angelo A Izzo Andrew J Lawrence David J MacEwan Lawrence D F Moon Sue Wonnacott Arthur H Weston John C McGrath 《British journal of pharmacology》2015,172(14):3461-3471
102.
103.
Filippo M. Cauti MD Pietro Rossi MD Carmelo La Greca MD Agostino Piro MD Natale Di Belardino MD Alberto Battaglia MD Federico Ferraris MD Domenico Pecora MD Carlo Lavalle MD Antonio Scalone MD Luca Rossi MD Andrea Di Cori MD Francesco Solimene MD Roberto Mantovan MD Stefano Pedretti MD Luigi Iaia MD Stefano Bianchi MD Matteo Anselmino MD 《Journal of cardiovascular electrophysiology》2021,32(5):1296-1304
104.
105.
Laura Di Domenico Chiara E Sabbatini Giulia Pullano Daniel Lvy-Bruhl Vittoria Colizza 《Euro surveillance : bulletin européen sur les maladies transmissibles = European communicable disease bulletin》2021,26(15)
Following the spread of the SARS-CoV-2 B.1.1.7 variant, social distancing was strengthened in France in January 2021. Using a two-strain mathematical model calibrated on genomic surveillance, we estimated that curfew measures allowed hospitalisations to plateau by decreasing transmission of the historical strains while B.1.1.7 continued to grow. School holidays appear to have further slowed down progression in February. Without progressively strengthened social distancing, a rapid surge of hospitalisations is expected, despite the foreseen increase in vaccination rhythm. 相似文献
106.
Francesco Solimene MD Mario Giannotti Santoro MD Antonio De Simone MD Maurizio Malacrida MSc Giuseppe Stabile MD Claudio Pandozi MD Gemma Pelargonio PhD MD Filippo Maria Cauti MD Marco Scaglione MD Domenico Pecora MD Maria Grazia Bongiorni MD Alberto Arestia MD Gabriella Grimaldi MD Maurizio Russo MD Maria Lucia Narducci PhD MD Luca Segreti MD 《Journal of cardiovascular electrophysiology》2021,32(6):1540-1548
107.
Ceci F Picchio M Palimento D Calì B Corelli S Spaziani E 《Diseases of the colon and rectum》2008,51(7):1107-1112
Purpose This study was designed to assess the long-term results of stapled hemorrhoidopexy in 291 patients with Grade III and Grade
IV hemorrhoids after a minimum follow-up of five years.
Methods Records of patients submitted to stapled hemorrhoidopexy for Grade III and Grade IV hemorrhoids between January 1999 and December
2002 were retrospectively analyzed. Long-term outcome was evaluated with a standardized questionnaire and an office visit,
including anorectal examination and rigid proctoscopy.
Results A total of 291 patients with Grade III (57.4 percent) and Grade IV (42.6 percent) hemorrhoids were evaluated. Intraoperative
(20.3 percent) and postoperative (4.8 percent) bleeding was the most frequent complication. The questionnaire was submitted
to all patients at a median follow-up of 73 (range 60–93) months. There were no symptoms related to hemorrhoids in 65.3 percent
of patients, moderate symptoms in 25.4 percent of patients, and severe symptoms in 9.3 percent of patients. Fifty-three (18.2
percent) patients had recurrence. Reoperation was necessary in 21 (7.2 percent) patients (4 in Grade III hemorrhoids and 17
in Grade IV hemorrhoids; P < 0.001), with no recurrent symptoms and/or prolapse. Patient satisfaction for operation was 89.7 percent.
Conclusions Stapled hemorrhoidopexy is a safe and effective treatment for Grade III and Grade IV hemorrhoids. Recurrence requiring reoperation
was higher in Grade IV hemorrhoids than in Grade III hemorrhoids.
Reprints are not available. 相似文献
108.
Prothrombin antigen levels in symptomatic and asymptomatic carriers of the 20210A prothrombin variant 总被引:9,自引:0,他引:9
Paolo Simioni Daniela Tormene Davide Manfrin Sabrina Gavasso Sonia Luni Domenico Stocco & Antonio Girolami 《British journal of haematology》1998,103(4):1045-1050
A recently discovered variant in the prothrombin gene (20210A) has been found in approximately 5–10% of patients with venous thromboembolism. It has been shown that patients with this variant present with high levels of prothrombin in plasma and this is maintained to be the most likely mechanism by which the risk of thrombosis is increased. We have evaluated prothrombin antigen levels in 50 carriers of the 20210A allele and compared with non-carriers. 327 subjects were subdivided according to deficiency status and previous thrombosis. 30 symptomatic and 20 asymptomatic carriers had increased mean prothrombin levels as compared to symptomatic ( n = 178) or asymptomatic ( n = 99) non-carriers. The percentage of subjects with prothrombin levels above cut-off values of 1.15 u/ml or 1.30 u/ml was significantly higher in carriers of the prothrombin variant as compared to non-carriers, regardless of a previous thrombosis. However, among non-carriers the percentage of those with prothrombin levels above cut-off values was significantly higher in the group of symptomatic as compared to asymptomatic individuals. In conclusion, increased prothrombin antigen levels, as detected by a specific ELISA, were found among 50 symptomatic and asymptomatic carriers of the 20210A prothrombin variant as well as among a large group of symptomatic non-carriers. The data are in agreement with those found by using functional tests for the determination of prothrombin levels in these patients. 相似文献
109.
Di Candia Domenico Boracchi Michele Ciprandi Barbara Giordano Gaia Zoja Riccardo 《International journal of legal medicine》2022,136(5):1291-1296
International Journal of Legal Medicine - Synthetic cathinones are a class of psychoactive drugs that have become, in recent years, of quite common observation in medical and toxicological forensic... 相似文献
110.
Francesco Minni Riccardo Casadei Barbara Perenze Vincenzo Maria Greco Nicola Marrano Alessandra Margiotta Domenico Marrano 《Pancreatology》2004,4(6):509-520
BACKGROUND: The aim of the study is to analyze pancreatic metastases and their clinical, radiological, therapeutic and prognostic features. METHODS: Three cases of pancreatic metastases observed and a world literature review of 333 cases were recorded. RESULTS: Pancreatic metastases are due more frequently to renal cell carcinoma; they are usually metachronous and characterized by a long period of time between the resection of the primary tumor and their detection. The differential diagnosis with other pancreatic masses is difficult, but an accurate anamnesis, some peculiar findings of imaging techniques and percutaneous fine needle aspiration could allow preoperative diagnosis. Pancreatic resections are the treatment of choice allowing the better palliation and improving survival. 150/234 pancreatic metastases underwent pancreatic resections (resectability index = 64.1%); 88/132 patients are alive with a mean follow-up of 27.1 months; of the 44 dead patients the mean survival time was 21.3 months. Among pancreatic metastases the primary tumor with better prognosis is renal cell carcinoma. CONCLUSION: Pancreatic metastases are rare; their preoperative diagnosis is difficult but useful and possible. Surgical resection is suggested because the patient still may have a prolonged survival. 相似文献