全文获取类型
收费全文 | 1503篇 |
免费 | 67篇 |
国内免费 | 13篇 |
专业分类
耳鼻咽喉 | 16篇 |
儿科学 | 144篇 |
妇产科学 | 11篇 |
基础医学 | 127篇 |
口腔科学 | 16篇 |
临床医学 | 88篇 |
内科学 | 251篇 |
皮肤病学 | 39篇 |
神经病学 | 96篇 |
特种医学 | 123篇 |
外科学 | 178篇 |
综合类 | 67篇 |
预防医学 | 64篇 |
眼科学 | 19篇 |
药学 | 235篇 |
中国医学 | 25篇 |
肿瘤学 | 84篇 |
出版年
2023年 | 6篇 |
2022年 | 13篇 |
2021年 | 35篇 |
2020年 | 10篇 |
2019年 | 25篇 |
2018年 | 30篇 |
2017年 | 19篇 |
2016年 | 18篇 |
2015年 | 22篇 |
2014年 | 34篇 |
2013年 | 37篇 |
2012年 | 78篇 |
2011年 | 80篇 |
2010年 | 42篇 |
2009年 | 50篇 |
2008年 | 81篇 |
2007年 | 65篇 |
2006年 | 76篇 |
2005年 | 63篇 |
2004年 | 52篇 |
2003年 | 46篇 |
2002年 | 50篇 |
2001年 | 43篇 |
2000年 | 31篇 |
1999年 | 35篇 |
1998年 | 49篇 |
1997年 | 32篇 |
1996年 | 32篇 |
1995年 | 18篇 |
1994年 | 30篇 |
1993年 | 23篇 |
1992年 | 43篇 |
1991年 | 39篇 |
1990年 | 34篇 |
1989年 | 29篇 |
1988年 | 30篇 |
1987年 | 16篇 |
1986年 | 17篇 |
1985年 | 19篇 |
1984年 | 8篇 |
1983年 | 7篇 |
1982年 | 15篇 |
1981年 | 10篇 |
1980年 | 9篇 |
1978年 | 10篇 |
1971年 | 5篇 |
1970年 | 7篇 |
1969年 | 7篇 |
1968年 | 6篇 |
1966年 | 5篇 |
排序方式: 共有1583条查询结果,搜索用时 0 毫秒
101.
Thioacetamide (100 mg/kg), when administered to normal rats, caused a significant increase in the activities of 5'-nucleotidase and gamma-glutamyl transpeptidase and a decrease in the activities of glucose 6-phosphatase and succinate dehydrogenase enzymes in the liver. DNA, RNA, and proteins were increased while the cytochrome P450 in the microsomal fraction and the glycogen content in the liver were decreased significantly. Elevations in the activities of GOT, GPT, and alkaline phosphatase and bilirubin content in serum were also observed. Picroliv, a standardised glycoside fraction of Picrorhiza kurroa, in doses of 12.5 and 25 mg/kg prevented most of the biochemical changes induced by thioacetamide in liver and serum. The hepatoprotective activity of Picroliv was comparable with that of silymarin, a known hepatoprotective agent obtained from seeds of Silybum marianum. 相似文献
102.
A 2-year-old girl with cyanotic congenital heart disease needed to undergo gastrostomy. To avoid the use of general anesthesia, a percutaneous gastrostomy was performed as an interventional radiologic procedure with the patient under sedation and with the use of local anesthesia. The placement of a nasogastrocutaneous guide wire under fluoroscopic guidance provided a stable tract for placement of the gastrostomy tube. 相似文献
103.
A whole blood method requiring less than 4 ml of heparinized blood was developed to assess the practicality of preparing whole blood samples that could be easily stored, transported and readily used to determine the lymphocyte phenotypes and proliferation responses of individuals from remote areas who are infected with the human immunodeficiency virus. Minor modifications in standard whole blood procedure for lymphocyte phenotyping have significantly increased the stability of light scatter and fluorescence intensity of the cells for subsequent flow cytometry (FC) analysis. These changes include removal of lysis solution prior to fixation, fixation of monoclonal antibody-stained cells in 1% paraformaldehyde for 30 minutes and storage of fixed samples in medium containing 1% bovine serum albumin. Lymphocyte subsets and their functional subsets could reliably be determined on samples stored for up to 4 weeks. Further, blood samples could be kept at room temperature for up to 96 hours or at ambient temperature during transportation from Africa before staining for FC without affecting their quantitation. While samples could be processed for FC analysis under field-laboratory conditions, proliferation assays could only be performed on samples that were transported within 48 hours of their collection. The whole blood method saves time and expense and decreases the volumes of blood required to perform phenotypic analysis and functional assays on specimens collected in remote areas. 相似文献
104.
105.
Hypotensive activity of 2-(2-(4-(3-methylphenyl)-1-piperazinyl)ethyl) quinoline (compound 71/73; centhaquin) was studied in cat and rat. The compound lowered the blood pressure and reduced the heart rate of anaesthetized and unanaesthetized (decerebrate) cat in a dose-dependent manner (0.01-1.0 mg/kg i.v. or 1.0-2.5 mg/kg intraduodenally). The hypotensive effect was insignificant in spinal transected cat but more marked in deafferented and vagotomized animals. Localization of centhaquin to brain by intravertebral arterial injection (5-10 micrograms) or by topical application to the exposed ventral surface of medulla or floor of the fourth ventricle caused hypotension and bradycardia as well as reduced the excitability of the vasomotor loci. It was also effective in rats after single as well as multiple dosing. The compound seems to act centrally to reduce the blood pressure. 相似文献
106.
107.
108.
109.
110.