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DESIGN: The ability of performance on the emotional Stroop task to predict subsequent levels of symptomatology was examined within a longitudinal design in a group of individuals with SAD. Participants were tested in the winter when depressed and again in the summer when remitted. RESULTS: There was no change in emotional Stroop performance across the two time points. However, winter performance on the emotional Stroop task predicted symptom levels in the summer, even with winter symptom levels partialled out. The nature of this relationship was that a greater emotional Stroop effect for threat words in the winter was related to more improved mood in the summer. Furthermore, the strength of the relationship between lower winter emotional Stroop performance and more negative winter mood was associated with poorer mood in the summer. 相似文献
53.
Prostate cancer continues to be a major cause of morbidity and mortality. Surgical and medical management of the disease has improved but there is little effect upon overall survival. Novel therapies such as immunotherapy offer the potential of treating the disease by stimulating the immune system to mount a response to the cancer systemically. This review highlights the pitfalls and progress in the understanding of the role of the immune system in malignancy and also explains the theory behind prostate cancer vaccine trials. 相似文献
54.
A history of pet contact and/or apparent clinical sensitivity was obtained in 65 (55%) of 118 unselected asthmatic children. These 65 children were skin tested and their sera examined for specific IgE using the radioallergosorbent test. Those children who had apparent clinical sensitivities had larger skin test reactions and were more likely to have positive specific IgE results than those without apparent sensitivities. Positive skin tests were very common (80%), but the larger the skin test reaction (weal diameter greater than 4 mm diameter) the more likely was there to be a positive history or a positive specific IgE result. Hence a large skin test reaction can provide a helpful pointer to animal allergy of clinical importance. Commercially available animal extracts have limitations for diagnostic tests. A questionnaire survey of 150 day schools emphasized the potential opportunities for contact with animal allergens at school. 相似文献
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A Baydur M N Koss O P Sharma G E Dalgleish D V Nguyen F G Mullick L A Murakata J A Centeno 《The European respiratory journal》2005,26(2):351-353
Indwelling catheters can disintegrate into tiny fragments and embolise. Once the fragments are detected radiographically, they can be removed using vascular intervention techniques. Rarely, indwelling catheters dwindle into inextricable pieces that embolise into minute pulmonary vessels and lymphatics, causing granulomatous changes microscopically. The present study reports a 54-yr-old female who had received several indwelling central lines during several abdominal surgeries over a 5-yr period. The patient developed a noncaseating granulomatous skin lesion followed by exertional dyspnoea a few months later. Chest radiographs and computed tomography showed diffuse interstitial infiltrates. Open lung biopsy showed two types of granulomas: 1) peri-lymphangitic and peri-bronchiolar non-necrotising granulomas consistent with sarcoidosis; and 2) distinct foreign body granulomas. In some of the foreign body granulomas, confocal Raman spectroscopy identified the presence of bisphenol-A-polycarbonate, a polymer commonly used in biomedical devices. The patient improved following treatment with prednisone followed by methotrexate. The present case illustrates an interesting combination of two causes of granulomatous disease, the importance of examining all biopsy specimens from sarcoidosis patients for foreign particles and the rare occurrence of microscopic embolisation of catheter fragments to the lung with foreign-body giant cell reaction to them. 相似文献
58.
AG Dorsten 《MedR Medizinrecht》2005,23(2):102
Abstrakt Es besteht kein Auskunftsanspruch des Patienten, der die Geltendmachung von Schadensersatzansprüchen aufgrund ärztlicher Fehlbehandlung beabsichtigt, auf Bekanntgabe der Berufshaftpflichtversicherung sowie der Versicherungsvertragsnummer gegenüber dem Arzt. Der Patient muss sich vielmehr zur Geltendmachung seiner Schadensersatzansprüche an den behandelnden Arzt selbst wenden. (Leitsätze des Bearbeiters) 相似文献
59.
A G Dalgleish 《Current opinion in immunology》1991,3(4):543-546
The past year has seen the discovery of new isolates which do not readily fit into the established categories HIV-1, HIV-2 and SIV, as well as the availability of new assays including the use of the polymerase chain reaction. New combination enzyme-linked immunosorbent assays can detect viruses from two or more groups where specific enzyme-linked immunosorbent assays have been developed using peptides and monoclonal antibodies. 相似文献
60.
Three cases are presented in which double-contrast esophagograms revealed one or more plaquelike lesions in the distal esophagus, representing pseudomembrane formation in patients with severe reflux esophagitis. Although to our knowledge this finding has not been reported previously in the radiologic literature, pseudomembranes have been documented endoscopically in patients with reflux esophagitis and biopsy-proved Barrett esophagus. Radiologists should be aware of this finding, since these pseudomembranes may be indistinguishable radiographically from plaquelike carcinomas arising in Barrett esophagus. 相似文献