全文获取类型
收费全文 | 398524篇 |
免费 | 26920篇 |
国内免费 | 4598篇 |
专业分类
耳鼻咽喉 | 5329篇 |
儿科学 | 8368篇 |
妇产科学 | 10344篇 |
基础医学 | 55658篇 |
口腔科学 | 11997篇 |
临床医学 | 32984篇 |
内科学 | 80976篇 |
皮肤病学 | 8710篇 |
神经病学 | 28377篇 |
特种医学 | 14730篇 |
外国民族医学 | 95篇 |
外科学 | 62435篇 |
综合类 | 13561篇 |
现状与发展 | 6篇 |
一般理论 | 65篇 |
预防医学 | 18774篇 |
眼科学 | 10063篇 |
药学 | 33369篇 |
30篇 | |
中国医学 | 3681篇 |
肿瘤学 | 30490篇 |
出版年
2021年 | 3779篇 |
2020年 | 2585篇 |
2019年 | 3437篇 |
2018年 | 5252篇 |
2017年 | 4171篇 |
2016年 | 4198篇 |
2015年 | 5062篇 |
2014年 | 6981篇 |
2013年 | 8476篇 |
2012年 | 11548篇 |
2011年 | 12038篇 |
2010年 | 7321篇 |
2009年 | 6804篇 |
2008年 | 10565篇 |
2007年 | 11359篇 |
2006年 | 11299篇 |
2005年 | 10382篇 |
2004年 | 9468篇 |
2003年 | 9184篇 |
2002年 | 8724篇 |
2001年 | 28679篇 |
2000年 | 29222篇 |
1999年 | 24108篇 |
1998年 | 5448篇 |
1997年 | 4559篇 |
1996年 | 4066篇 |
1995年 | 3715篇 |
1994年 | 3307篇 |
1993年 | 2957篇 |
1992年 | 16166篇 |
1991年 | 14886篇 |
1990年 | 14234篇 |
1989年 | 14027篇 |
1988年 | 12633篇 |
1987年 | 12101篇 |
1986年 | 11141篇 |
1985年 | 10340篇 |
1984年 | 6919篇 |
1983年 | 5604篇 |
1982年 | 2723篇 |
1979年 | 5481篇 |
1978年 | 3345篇 |
1977年 | 2963篇 |
1975年 | 2636篇 |
1974年 | 3064篇 |
1973年 | 2863篇 |
1972年 | 2828篇 |
1971年 | 2773篇 |
1970年 | 2509篇 |
1969年 | 2543篇 |
排序方式: 共有10000条查询结果,搜索用时 281 毫秒
991.
W.-S. Ahn D.-J. Kim† G.-T. Chae‡ J.-M. Lee S.-M. Bae§ J.-I. Sin§ Y.-W. Kim§ S.-E. Namkoong & I. P. Lee 《International journal of gynecological cancer》2004,14(4):589-594
A mushroom extract, Agaricus blazei Murill Kyowa (ABMK), has been reported to possess antimutagenic and antitumor effects. Here, we investigate the beneficial effects of ABMK consumption on immunological status and qualities of life in cancer patients undergoing chemotherapy. One hundred cervical, ovarian, and endometrial cancer patients were treated either with carboplatin (300 mg / m(2)) plus VP16 (etoposide, 100 mg / m(2)) or with carboplatin (300 mg / m(2)) plus taxol (175 mg / m(2)) every 3 weeks for at least three cycles with or without oral consumption of ABMK. We observed that natural killer cell activity was significantly higher in ABMK-treated group (ANOVA, n = 39, P < 0.002) as compared with nontreated placebo group (n = 61). However, no significant difference in lymphokine-activated killer and monocyte activities was observed in a manner similar to the count of specific immune cell populations between ABMK-treated and nontreated groups. However, chemotherapy-associated side effects such as appetite, alopecia, emotional stability, and general weakness were all improved by ABMK treatment. Taken together, this suggests that ABMK treatment might be beneficial for gynecological cancer patients undergoing chemotherapy. 相似文献
992.
M.S. Ågren U. Ostenfeld M.E. Crawford K. Kiss Y. Gong C. Gluud A. FriisMøller F. Kallehave K. Raffn L.N. Jorgensen 《Wound repair and regeneration》2005,13(2):A1-A27
Extended healing time and lack of documented effective treatments of sacrococcygeal pilonidal disease create substantial problems. Locally applied zinc oxide has been reported to promote wound healing. We have compared topical zinc oxide (3%) with placebo meshes for pilonidal wounds healing by secondary intention in a randomized, double‐blind, placebo‐controlled multicenter trial. Sixty‐four consecutive patients, 53 males, aged between 18 and 60 years (median 26 years) with excised pilonidal wounds were centrally randomized to local zinc oxide (30 mg/g, n = 33) or to placebo (n = 31) mesh treatment. Patients were followed with strict recording of beneficial and harmful effects. The median healing times were 54 days (42–71 days, interquartile range, n = 33) for the zinc group and 62 days (55–82 days, n = 31) for the placebo group. This difference was not statistically different (p = 0.32). Based on Cox regression analysis initial wound volume influenced healing negatively (p = 0.016) while smoking (p = 0.011) was associated with faster wound healing. Significantly (p < 0.01) more placebo (n = 12) than zinc oxide‐treated patients (n = 3) needed antibiotics postoperatively. Although topical zinc oxide increased (p < 0.001) wound fluid zinc levels (1830 ± 405 μM, mean ± SEM) compared with placebo (3.1 ± 1.6 μM) serum‐zinc levels did not differ significantly between the zinc (13.5 ± 0.4 μM) and placebo (12.8 ± 0.4 μm) groups on postoperative day 7. No adverse events were recorded. Topical zinc oxide treatment did not accelerate time to closure of open pilonidal wounds but was associated with reduced antibiotic usage. 相似文献
993.
994.
995.
996.
997.
998.
K. Kim T. Mizunari N. Mizutani S. Kobayashi K. Takizawa H. Kamiyama Y. Murai A. Teramoto 《Acta neurochirurgica》2006,148(3):353-357
Summary We describe a giant aneurysm of the anterior communicating artery (ACoA) which was treated with a STA-RA graft-A3 bonnet bypass
and A3–A3 side-to-side anastomosis. A giant and partially thrombosed ACoA aneurysm was partially coated 3 years before his
current presentation, its gradual increase producing visual field disturbances. An A3–A3 side-to-side anastomosis and STA-RA
graft-A3 bonnet bypass were performed. The aneurysm was dissected, and the thrombus removed under transient parent-artery
occlusion. The aneurysmal neck was successfully clipped without encountering ischemic changes. This strategy may be useful
for treating giant or thrombosed aneurysms in the region of the ACoA. 相似文献
999.
Y Xu D Zagoura C Keck D Pietrowski 《Experimental and clinical endocrinology & diabetes》2006,114(10):590-595
Corpus luteum development is regulated by gonadotropins and accompanied by extremely rapid vascularization of the avascular granulosa cell compartiment by endothelial cells (EC). The proliferation of Granulosa cells (GC) and EC is a complex interplay and takes place in a spatially and temporarily coordinated manner. The erythropoietin-producing hepatoma amplified sequence (Eph) receptors and their ligands-the ephrins- are a recently detected family of membrane located protein tyrosine kinases which play a crucial role in the growth and development of nerve and blood vessel network. We report about the mRNA expression pattern of Ephs and their ligands in human GC, in human EC, and in carcinoma cell lines OvCar-3 and Hela. The mRNA of EphA4, EphA7, ephrinA4, ephrinB1 and ephrinB2 was detected in GC and EC, while EphA2 was expressed only in GC. The expression of various Ephs and ephrins did not change in GC after stimulation with human chorion gonadotropin. Our study analyzes for the first time the expression of the complete human Eph/ephriny-system in GC and in EC. The remarkable similarity between these two cell types supports the theory of a functional relationship of EC and GC. In addition, it was shown that hCG is not a major determinant of Eph/ephrin regulation in GC. 相似文献
1000.