全文获取类型
收费全文 | 16780篇 |
免费 | 1462篇 |
国内免费 | 44篇 |
专业分类
耳鼻咽喉 | 167篇 |
儿科学 | 438篇 |
妇产科学 | 369篇 |
基础医学 | 2374篇 |
口腔科学 | 376篇 |
临床医学 | 1826篇 |
内科学 | 3658篇 |
皮肤病学 | 291篇 |
神经病学 | 1276篇 |
特种医学 | 713篇 |
外国民族医学 | 17篇 |
外科学 | 2297篇 |
综合类 | 175篇 |
一般理论 | 6篇 |
预防医学 | 1562篇 |
眼科学 | 196篇 |
药学 | 1105篇 |
中国医学 | 21篇 |
肿瘤学 | 1419篇 |
出版年
2022年 | 108篇 |
2021年 | 266篇 |
2020年 | 180篇 |
2019年 | 277篇 |
2018年 | 355篇 |
2017年 | 248篇 |
2016年 | 311篇 |
2015年 | 352篇 |
2014年 | 435篇 |
2013年 | 583篇 |
2012年 | 841篇 |
2011年 | 862篇 |
2010年 | 481篇 |
2009年 | 448篇 |
2008年 | 741篇 |
2007年 | 758篇 |
2006年 | 739篇 |
2005年 | 733篇 |
2004年 | 677篇 |
2003年 | 694篇 |
2002年 | 641篇 |
2001年 | 570篇 |
2000年 | 605篇 |
1999年 | 559篇 |
1998年 | 215篇 |
1997年 | 176篇 |
1996年 | 173篇 |
1995年 | 140篇 |
1994年 | 120篇 |
1993年 | 133篇 |
1992年 | 398篇 |
1991年 | 350篇 |
1990年 | 330篇 |
1989年 | 289篇 |
1988年 | 310篇 |
1987年 | 260篇 |
1986年 | 277篇 |
1985年 | 266篇 |
1984年 | 211篇 |
1983年 | 208篇 |
1982年 | 110篇 |
1981年 | 101篇 |
1980年 | 109篇 |
1979年 | 162篇 |
1978年 | 128篇 |
1977年 | 101篇 |
1975年 | 91篇 |
1974年 | 115篇 |
1973年 | 121篇 |
1971年 | 91篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
51.
Angelika Heese Ulrike Lacher Hans Uwe Koch Janna Kubosch Yasmin Ghane Klaus-Peter Peters 《Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete》1996,47(11):817-824
Zusammenfassung
Die Typ I-Allergien gegen Latex sind in den vergangenen Jahren zu einem zunehmenden berufsdermatologischen Problem geworden,
zumal mindestens 10% der Angestellten im Gesundheitswesen betroffen sind. In der Dermatologischen Klinik der Universit?t Erlangen-Nürnberg
stieg die Anzahl der j?hrlich diagnostizierten Patienten mit Latexallergien von 1989 bis 1995 auf das 12fache, wobei der Anteil
der schweren, generalisierten Formen der Erkrankung von 10,7% (1989/1990) auf 44% (1994/1995) zunahm.
Unter den m?glichen Ausl?sern der Latexallergie (wasserl?sliche Proteine mit Molekulargewichten von 2 bis 200 kD) sind mindestens
5 Hauptproteine mit bereits bekannter Prim?rstruktur zu berücksichtigen. Zus?tzlich gibt es Hinweise für Markerproteine, die
in bestimmten Risikogruppen geh?uft zur Ausl?sung spezifischer IgE-Antik?rper führen (z.B. 46 kD-Protein in medizinischen
Berufen, 14,6 kD- und 27 kD-Proteine bei Kindern mit Spina bifida). Das Vorkommen von Kreuzreaktionen zwischen Latex und unterschiedlichen
Früchten (besonders Avocado, Kiwi, Banane, E?kastanie) bei 60 bis 70% der Latexallergiker ist bei der allergologischen Abkl?rung
und Beratung dieser Patienten zu beachten. Wesentliche Aspekte der Prophylaxe umfassen die konsequente Umstellung medizinischer
Einrichtungen auf ungepuderte Latexhandschuhe mit niedrigem Proteingehalt. Eine Zusammenstellung von OP- und Untersuchungshandschuhen,
welche Angaben über die von uns ermittelten Proteinkonzentrationen (modifizierte Lowry-Methode und Hochdruck-Flüssigkeits-Chromatographie,
HPLC) enth?lt, soll ein Leitfaden bei der Auswahl allergologisch geeigneter Handschuhe sein.
Eingegangen am 10. August 1996 Angenommen am 21. August 1996 相似文献
52.
53.
Immunopathology of glomerulonephritis associated with chronic woodchuck hepatitis virus infection in woodchucks (Marmota monax).
下载免费PDF全文
![点击此处可从《The American journal of pathology》网站下载免费的PDF全文](/ch/ext_images/free.gif)
D. N. Peters H. Steinberg W. I. Anderson W. E. Hornbuckle P. J. Cote J. L. Gerin R. M. Lewis B. C. Tennant 《The American journal of pathology》1992,141(1):143-152
Retrospective analysis of necropsy findings of 705 woodchucks was performed to determine the prevalence and morphology of immune-mediated glomerulonephritis, its relationship to woodchuck hepatitis virus (WHV) infection, and the presence of major WHV antigens. Twenty-six woodchucks had glomerular lesions. Renal tissue of the 26 animals was evaluated histologically and immunohistochemically for immune-mediated glomerulonephritis. Of these 26 animals, immune-mediated glomerulonephritis was diagnosed in six, all of which were chronic WHV carriers. Membranous glomerulonephritis was identified in three animals, two of which also had mesangial proliferation. Host immunoglobulin was present within the mesangium and along capillary loops in all three. Woodchuck hepatitis virus core antigen (WHcAg) was present along capillary loops of two of these animals, one membranous and one mixed, and in the mesangium of all three. Woodchuck hepatitis virus surface antigen (WHsAg) deposition was similar to WHcAg deposition but was only present along capillaries in those animals with mixed nephritis. The remaining three animals had mesangial proliferation. WHsAg and host immunoglobulin deposition were predominately mesangial; WHcAg was not detected. Transmission electron microscopy showed thickening of the capillary loop basement membranes and subepithelial electron-dense deposits in animal one, and deposits in the mesangium in animal six. 相似文献
54.
55.
56.
In order to identify risk factors for preterm birth in singletons, data from a population-based case control survey on the island of Curacao were re-analysed. Both medical and sociodemographic variables were examined. Overall, a history of previous preterm birth and severe hypertension during the index pregnancy were indicators of adverse pregnancy outcome, in terms of preterm birth. The contribution of sociodemographic factors to the risk of preterm birth is relatively low. 相似文献
57.
58.
A comprehensive study of smoking in primary school children in Hong Kong: implications for prevention.
下载免费PDF全文
![点击此处可从《Journal of epidemiology and community health》网站下载免费的PDF全文](/ch/ext_images/free.gif)
J Peters A J Hedley T H Lam C L Betson C M Wong 《Journal of epidemiology and community health》1997,51(3):239-245
STUDY OBJECTIVE: To identify factors associated with smoking behaviour in primary school children in Hong Kong. DESIGN: A cross sectional survey in which both children and parents completed questionnaires. The main outcome measure was the smoking status of the children; and risk factors (knowledge of and attitude to smoking and demographic and socioeconomic background) were identified as predictors of ever/never smoking. SETTING AND SUBJECTS: Altogether 9598 primary school children, aged 8-13 years, and attending 27 schools from two districts in Hong Kong participated. MAIN RESULTS: The prevalence of ever-smoking was 12% (1119)-15% (760) in boys and 7% (359) in girls. It ranged from 3% in 8 year old girls to 52% in 13 year old boys. The factors associated with ever-smoking included the following: being a boy (adjusted odds ratio 2.21; 95% confidence interval 1.89, 2.59), increasing age per year (1.48; 1.40, 1.57), living in Kwai Tsing district (1.29; 1.10, 1.50), having one or more smokers at home (2.07; 1.78, 2.39), and having a father who was not working (1.41; 1.19, 1.67). Children who were ever-smokers had both seen and approved of their friends' smoking (8.79; 5.33, 14.50), had a more positive attitude towards smoking (3.35; 2.21, 5.09), and were more successful in recognising cigarette brand names and logos (1.67; 1.42, 1.96), but they lacked confidence (1.78; 1.32, 2.39). CONCLUSIONS: The influences on child smoking are multifactorial and programmes in Hong Kong are falling to curb them. The control of these risk factors must be incorporated in the smoking prevention policy of Hong Kong and supported by future enforced legislation. 相似文献
59.
Douglas M. Silverstein Ira Greifer Vaughn Folkert Boyce Bennett Howard E. Corey Adrian Spitzer 《Pediatric nephrology (Berlin, Germany)》1994,8(6):752-753
We report a patient who developed Henoch-Schönlein purpura (HSP) 13 years after he presented with IgA nephropathy (IgAN). In both HSP and IgAN renal biopsy most commonly reveals focal proliferative glomerulonephritis on light microscopy and immunofluorescence displays mesangial IgA deposits. In addition, patients with HSP or IgAN have elevated serum IgA levels, circulating IgA immune complexes, IgA-bearing lymphocytes, immunoglobulin-producing cells, and binding of IgG to glomerular components of similar molecular weight. The occurrence of both diseases in the same patient or the same families and the presence of immune abnormalities compatible with HSP or IgAN in relatives of patients with these diseases suggest a common pathogenesis. 相似文献
60.
Extended duration of herpes simplex virus DNA in genital lesions detected by the polymerase chain reaction. 总被引:18,自引:0,他引:18
R W Cone A C Hobson J Palmer M Remington L Corey 《The Journal of infectious diseases》1991,164(4):757-760
To evaluate the utility of the polymerase chain reaction (PCR) for documenting herpes simplex virus (HSV) in persons with reactivated genital lesions viral isolation was compared with a recently developed PCR method. Three women experiencing four episodes of recurrent genital herpes were followed for 10 days per episode with daily examination and duplicate swabs of the lesions, one for HSV culture and one for PCR. HSV type 2 was cultured from three of four episodes and the mean duration of viral isolation from recurrent genital lesions was 2.6 days. PCR detected HSV DNA from lesion swabs during all four episodes, and HSV DNA was positive for an average of 6.8 days. HSV DNA was demonstrated in ulcerative lesions on 15 of 17 days versus 3 of 17 days by viral isolation (P less than .01). HSV PCR became negative when the lesions reepithelialized. These data suggest that PCR is a more sensitive measure of HSV infection than routine viral culture and that PCR detects the presence of HSV at times when culture is negative. 相似文献