全文获取类型
收费全文 | 186907篇 |
免费 | 10805篇 |
国内免费 | 221篇 |
专业分类
耳鼻咽喉 | 2863篇 |
儿科学 | 6428篇 |
妇产科学 | 4659篇 |
基础医学 | 28120篇 |
口腔科学 | 5975篇 |
临床医学 | 17668篇 |
内科学 | 33524篇 |
皮肤病学 | 4851篇 |
神经病学 | 19391篇 |
特种医学 | 7221篇 |
外科学 | 26471篇 |
综合类 | 949篇 |
现状与发展 | 1篇 |
一般理论 | 72篇 |
预防医学 | 12306篇 |
眼科学 | 3832篇 |
药学 | 12604篇 |
中国医学 | 265篇 |
肿瘤学 | 10733篇 |
出版年
2023年 | 1080篇 |
2022年 | 970篇 |
2021年 | 2331篇 |
2020年 | 1925篇 |
2019年 | 2580篇 |
2018年 | 4191篇 |
2017年 | 3490篇 |
2016年 | 4331篇 |
2015年 | 3984篇 |
2014年 | 4750篇 |
2013年 | 7564篇 |
2012年 | 10114篇 |
2011年 | 11064篇 |
2010年 | 6321篇 |
2009年 | 4935篇 |
2008年 | 10656篇 |
2007年 | 11172篇 |
2006年 | 10713篇 |
2005年 | 10779篇 |
2004年 | 9954篇 |
2003年 | 9850篇 |
2002年 | 9578篇 |
2001年 | 5922篇 |
2000年 | 7073篇 |
1999年 | 4488篇 |
1998年 | 2118篇 |
1997年 | 1753篇 |
1996年 | 1381篇 |
1995年 | 1234篇 |
1994年 | 1148篇 |
1993年 | 1048篇 |
1992年 | 1495篇 |
1991年 | 1339篇 |
1990年 | 1347篇 |
1989年 | 1361篇 |
1988年 | 1193篇 |
1987年 | 1260篇 |
1986年 | 1081篇 |
1985年 | 1193篇 |
1984年 | 1108篇 |
1983年 | 916篇 |
1982年 | 814篇 |
1981年 | 785篇 |
1980年 | 712篇 |
1979年 | 816篇 |
1978年 | 684篇 |
1977年 | 677篇 |
1976年 | 594篇 |
1975年 | 621篇 |
1974年 | 628篇 |
排序方式: 共有10000条查询结果,搜索用时 532 毫秒
11.
Bela Anand-Apte Jennifer R. Chao Ruchira Singh Heidi Stöhr 《Journal of neuroscience research》2019,97(1):88-97
Sorsby fundus dystrophy (SFD), an autosomal dominant, fully penetrant, degenerative disease of the macula, is manifested by symptoms of night blindness or sudden loss of visual acuity, usually in the third to fourth decades of life due to choroidal neovascularization (CNV). SFD is caused by specific mutations in the Tissue Inhibitor of Metalloproteinase-3, (TIMP3) gene. The predominant histo-pathological feature in the eyes of patients with SFD are confluent 20–30 m thick, amorphous deposits found between the basement membrane of the retinal pigment epithelium (RPE) and the inner collagenous layer of Bruch's membrane. SFD is a rare disease but it has generated significant interest because it closely resembles the exudative or “wet” form of the more common age-related macular degeneration (AMD). In addition, in both SFD and AMD donor eyes, sub-retinal deposits have been shown to accumulate TIMP3 protein. Understanding the molecular functions of wild-type and mutant TIMP3 will provide significant insights into the patho-physiology of SFD and perhaps AMD. This review summarizes the current knowledge on TIMP3 and how mutations in TIMP3 cause SFD to provide insights into how we can study this disease going forward. Findings from these studies could have potential therapeutic implications for both SFD and AMD. 相似文献
12.
13.
14.
15.
Rocha Déborah Ribeiro Nery Jaqueline Freire Furini Leonardo Negri Constantino Carlos José Leopoldo Eller Lizziane Kretli Winkelströter Nai Gisele Alborghetti Nakagaki Wilson Romero 《Lasers in medical science》2020,35(8):1703-1709
Lasers in Medical Science - Studies reported the harmful effects of 2,4-D on body tissues, provoking changes in the anatomy and physiology of the kidneys, liver, and testicles. Thus, the objective... 相似文献
16.
17.
Jeffrey Buenaflor Parker Sommerville Hang Qian Christine Luscombe 《Macromolecular chemistry and physics.》2020,221(2)
A comparative study involving bimetallic nickel catalysts designed from disubstituted N,N,N′,N′‐tetra(diphenylphosphanylmethyl)benzene diamine bridging ligands is reported. Catalyst behavior is explored in the Kumada catalyst‐transfer polymerization (KCTP) using poly(3‐hexylthiophene) (P3HT) as the model system. The success of a controlled polymerization is monitored by analyzing monomer conversion, degree of polymerization, end‐group identity, and molecular weight distribution. The characterization of P3HT obtained from KCTP initiated with the bimetallic catalysts shows chain‐growth behavior; however, the presence of Br/Br end‐groups and broader molecular weight distribution reveals a reduced controlled polymerization compared to the commonly employed Ni(dppp)Cl2. The observed increase in intermolecular chain transfer and termination processes in KCTP initiation with the bimetallic catalysts can be attributed to a weaker Ni(0)‐π‐aryl complex interaction, which is caused by increased steric crowding of the coordination sphere. 相似文献
18.
19.