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111.
112.
Choe Seong Wook MD Cho Wan Ik MD Lee Chang Kyun MD † Seo Seong Jun MD 《Dermatologic surgery》2005,31(5):502-508
BACKGROUND: Masseteric muscle hypertrophy is an uncommon dition represented as a swelling of the masseter muscle. Recent reports have demonstrated the successful use of botulinum in the treatment of masseteric hypertrophy. OBJECTIVE: This study was a prospective trial to evaluate the effectiveness of botulinum toxin type A (Botox) in the treatment of masseteric muscle hypertrophy according to doses of 10, 20, and 30 U. MATERIALS AND METHODS: Twenty-two patients were referred to the dermatologic clinic for the management of masseteric muscle hypertrophy. Ultrasonographic measurements of the thickness of the masseter muscle were performed, and clinical photographs were taken before treatment and 1, 2, 3, 4, 6, and 9 months after the treatment. RESULTS. The median values of percentage reduction of muscle mass were 10.3%, 16.5%, 23.7%, 24.7%, 21.6%, 16.5% in the 10 U group; 11.9%, 18.8%, 24.8%, 27.7%, 26.7%, and 21.8% in the 20 U group; and 12.0%, 19.4%, 25.0%, 27.8%, 37.8%, and 24.1% in the 30 U group. CONCLUSION. The adequate dose of botulinum toxin type A for treatment of masseteric muscle hypertrophy should be above 20 U. The effect of botulinum toxin type A is maintained for at least 9 months as the treatment of masseteric muscle hypertrophy. 相似文献
113.
消化道类癌的诊断与治疗(附44例报告) 总被引:3,自引:0,他引:3
目的探讨消化道类癌的诊断与治疗. 方法回顾性分析我院1990年1月~2005年4月44例消化道类癌的临床资料. 结果本组44例中直肠(包括直肠乙状结肠交界处)类癌29例发生率最高65.9%(29/44),结肠4例9.1%(4/44),阑尾1例2.3%(1/44),小肠2例4.5%(2/44),十二指肠2例4.5%(2/44),胃5例11.4%(5/44),肝1例2.3%(1/44).44例中治疗了39(39/44,88.6%),其中手术切除14例,内镜下粘膜切除术(EMR)20例(5例EMR后病理断端残余癌细胞又追加手术局部切除),内镜下直接钳除5例,5例未治疗.直径≤1 cm 30例占68.2%, 26例全部治愈,15例(50%)行EMR完全切除,其中20例肠镜随访10~84个月,均无复发,预后好;直径1~2 cm 4例占9.1%,手术局部切除,1例1年后肝转移;直径>2 cm 10例占22.7%,均位于直肠外,8例手术,2例未治疗,3例死亡,5例有远处或淋巴结转移,预后差.44例中6例发生远处或淋巴结转移,转移率13.6%. 结论内镜是诊断消化道类癌的首选方法,≤1cm的类癌可在内镜下行EMR切除. 相似文献
114.
Zhang Ying-lin张应霖 Liao Da-mei廖大美 Wei Yong-gui魏永贵and Bai Guo-rong白国荣Luzhou Medical College Sichuan 《中华医学杂志(英文版)》1987,100(1):56-57
In 1980, 267 patients with related symp-
toms were examined by tomography in our hos-
pital. Among them the styloid process (SP) of
128 cases were 30 mm or more in length. Pha-
ryngeal palpation was performed in 98. The SPs
of 61 patients were palpable and tender. Diagno-
sis was based on the related symptoms, tomogra-
phy, positive pharyngeal palpation and SP tender-
ness. Tomography showed that the longest SP
was 75 mm, while the longest one with symptoms
was 65 mm. The medial angulations of the SPs
were from 100 t0 27° and the anterior angulations
from 300 t0 50°. 相似文献
115.
S F Viegas A F Tencer J Cantrell M Chang P Clegg C Hicks C O'Meara J B Williamson 《The Journal of hand surgery》1987,12(6):978-985
An experimental model with a static positioning frame, pressure-sensitive film (Fuji), and a microcomputer-based video digitizing system, previously developed by the two senior authors, was used in this study to examine the effects of increasing perilunate instability on the load transfer characteristics of the wrist. These effects included a significant dorsal ulnar shift of the scaphoid centroid with increasing perilunate instability together with a less dramatic palmar ulnar shift of the lunate centroid. Overall, the scaphoid contact area was found to decrease as the stage of perilunate instability increased, even in ulnar deviation and/or extension, which in the normal wrist was found to be the positions that had the greatest scaphoid contact area. Average pressures in the high pressure zones were found to significantly increase in wrists with a stage III instability compared with normal wrists. An increase in the intercentroid (scaphoid/lunate) distance was most evident with the wrist in 20 degrees extension, neutral radioulnar deviation, and 90 degrees supination. 相似文献
116.
LHRH-PE40识别结肠癌细胞膜表面蛋白的研究 总被引:1,自引:0,他引:1
目的探讨人结肠癌细胞系Lovo及人白血病细胞系Jurket细胞膜表面蛋白能否识别LHRH-PE40及是否存在竞争性抑制。方法将结肠癌细胞系Lovo及白血病细胞系Jurket制备成细胞膜,利用125I标记的LHRH-PE40与两种细胞膜进行放射性配基分析,与LHRH进行竞争结合分析。结果人结肠癌细胞系Lovo的结合竞争符合特异性配基-受体结合、竞争;而白血病细胞系Jurket未见配基-受体特异性结合。其中LHRH-PE40与Lovo细胞的亲和力:Kd=10·6±2·33nmol/L,容量Bmax=345±7·59pmol/mg。结论LHRH是结肠癌免疫治疗的有效靶点,LHRH-PE40对过度表达LHRH受体的结肠癌具有特异性杀伤作用,而对无LHRH表达的肿瘤无杀伤作用,对于药物的临床应用有着指导意义。 相似文献
117.
118.
119.
Sixty strains of Riemerella anatipestifer were isolated from ducks and geese with infectious serositis in Taiwan. Sixty per cent of the isolates (36/60) contained a 3.9 b plasmid, 12% (7/60) contained 6.5 b and 16 b plasmids, 5% (3/60) contained 2.9, 16 and 18 b plasmids and 13% contained no plasmid (14/60). The 3.9 b plasmid (designated as pCFC1) was completely sequenced to determine if it encoded virulence factors. pCFC1 was 27% G-C and had four large open reading frames (ORF). Two of the ORFs (designated as VapD1 and VapD2) encoded proteins that shared 80, 83, 69 and 67 (VapD1) and 50, 48, 21 and 20% (VapD2) identity with virulence-associated proteins of Actinobacillus Actinomycetemcomitans, Dichelobcater nodosus, Haemophilus influenzae and Neisseria gonorrheae, respectively. pCFC1 also had an ORF (designated as RepAl) that encoded a protein with approximately 30% identity to the RepA proteins of Neisseria gonorrhoeae, Campylobactor hyointestinalis and Pseudomonas aeroginosa. The region upstream of the RepA ORF had an A-T-rich region that was followed by four 21 bp perfect and one 20 bp imperfect direct repeat. The fourth ORF (designated as RepA2) encoded a protein with a region that was 44% homologous to the Helicobactor pylori replication protein. 相似文献
120.
牛骨形成蛋白在骨不连中的临床应用 总被引:2,自引:0,他引:2
应用牛骨形成蛋白(bovineBoneMorphogeneticProtein简称b-BMP)成功的治愈13例骨不连病人。经过13个月~29个月随访观察,效果较好。本组病人术前平均已做过1.5次手术。13例病人中,有12例被1次治愈。1例病人再次行内固定加用牛骨形成蛋白的植入也被治愈。骨形成蛋白的应用方式,采用同锻石膏复合后植入骨不连处。平均每个病人植入100mgBMP,13例病人平均治愈时间为4.7个月。术后没有任何并发症。 相似文献