全文获取类型
收费全文 | 456篇 |
免费 | 22篇 |
国内免费 | 7篇 |
专业分类
儿科学 | 7篇 |
妇产科学 | 5篇 |
基础医学 | 34篇 |
口腔科学 | 5篇 |
临床医学 | 54篇 |
内科学 | 92篇 |
皮肤病学 | 9篇 |
神经病学 | 15篇 |
特种医学 | 157篇 |
外科学 | 25篇 |
综合类 | 2篇 |
预防医学 | 12篇 |
眼科学 | 2篇 |
药学 | 43篇 |
肿瘤学 | 23篇 |
出版年
2022年 | 2篇 |
2021年 | 3篇 |
2020年 | 3篇 |
2019年 | 3篇 |
2018年 | 8篇 |
2016年 | 4篇 |
2015年 | 7篇 |
2014年 | 4篇 |
2013年 | 13篇 |
2012年 | 13篇 |
2011年 | 11篇 |
2010年 | 9篇 |
2009年 | 12篇 |
2008年 | 12篇 |
2007年 | 12篇 |
2006年 | 18篇 |
2005年 | 12篇 |
2004年 | 7篇 |
2003年 | 5篇 |
2002年 | 6篇 |
2001年 | 6篇 |
2000年 | 8篇 |
1999年 | 4篇 |
1998年 | 16篇 |
1997年 | 24篇 |
1996年 | 23篇 |
1995年 | 14篇 |
1994年 | 21篇 |
1993年 | 12篇 |
1992年 | 6篇 |
1991年 | 11篇 |
1990年 | 9篇 |
1989年 | 23篇 |
1988年 | 18篇 |
1987年 | 10篇 |
1986年 | 21篇 |
1985年 | 15篇 |
1984年 | 15篇 |
1983年 | 7篇 |
1982年 | 14篇 |
1981年 | 6篇 |
1980年 | 6篇 |
1979年 | 2篇 |
1978年 | 5篇 |
1977年 | 9篇 |
1976年 | 6篇 |
1975年 | 6篇 |
1971年 | 1篇 |
1961年 | 1篇 |
1935年 | 1篇 |
排序方式: 共有485条查询结果,搜索用时 15 毫秒
91.
92.
93.
94.
B-mode ultrasound scanning was studied as a noninvasive means of determining skin thickness in the extremities of patients with progressive systemic sclerosis. Skin thickness determined by ultrasonic scanning was compared with skin thickness determined by an established radiographic technique. A high degree of correlation was observed between measurements made by these techniques. Our studies suggest a potential application of B-mode ultrasound in the diagnosis and serial evaluation of patients with progressive systemic sclerosis. 相似文献
95.
Edelman RR; Wedeen VJ; Davis KR; Widder D; Hahn P; Shoukimas G; Brady TJ 《Radiology》1986,161(3):779-783
A new technique is described that allows for the creation of pure pulsatile flow magnetic resonance (MR) images in a single acquisition. Five to 16 electrocardiographically gated images spanning the entire cardiac cycle are obtained with use of a gradient-echo pulse sequence. The section can be varied from 4 mm thick to full thickness projection. Taken singly, each image provides direct assessment of flow direction and velocity. Subtraction of image pairs eliminates signal detected from stationary protons, producing images of pulsatile flow. In this study the technique was used to image the flow of cerebrospinal fluid (CSF) in healthy subjects and in one patient with syringohydromyelia. The data suggest that multiphasic MR imaging provides a powerful means for the noninvasive assessment of CSF pulsatile flow dynamics and may have potential clinical application for the investigation of a variety of abnormalities such as normal pressure hydrocephalus, syrinx, and spinal block. 相似文献
96.
97.
Meuli RA; Wedeen VJ; Geller SC; Edelman RR; Frank LR; Brady TJ; Rosen BR 《Radiology》1986,159(2):411-418
We report the first clinical experience with a new method for projective imaging of blood vessels (angiography) using magnetic resonance. Vascular contrast is produced noninvasively by the phase response of moving protons. Diastolic and systolic gated images produce, respectively, flow signal and flow void; the difference image is a map of the pulsatile flow: an arteriogram. Preliminary studies are presented of the lower extremities of one healthy volunteer and four patients (one each with occlusive disease, soft-tissue tumor, arteriovenous malformation, and venous femoral-popliteal graft). Patient data are compared with accompanying conventional arteriograms, and the new method is discussed. 相似文献
98.
99.
Kristin L Bigos Robert R Bies Bruce G Pollock 《The American journal of geriatric psychiatry》2006,14(12):993-1003
Although geriatric patients are the major recipients of drugs, most research during drug development is conducted in healthy younger adults. Safe and effective drug therapy in the elderly requires an understanding of both drug disposition and response in older individuals. One of the major issues in studying the elderly relates to the ability to study a large number of people in a minimally invasive way. Population pharmacokinetics can be used to model drug concentrations from a large population of sparsely sampled individuals. Population pharmacokinetics characterizes both the interindividual (between-subject) and intraindividual (within-subject) variability, and can identify factors that contribute to pharmacokinetic and pharmacodynamic variability. Population pharmacokinetics can be used to aid in designing large clinical trials by simulating virtual data based on the study design. It can also be used to assess consistency of drug exposure and evaluate its effect on clinical outcome. This article reviews the methods used in pharmacokinetic modeling, as well as providing examples of population pharmacokinetic modeling, highlighting its application to geriatric psychiatry. 相似文献
100.