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991.
Dermatofibroma (DF) is a very common lesion of the skin and presents in many guises that might cause problems in differential diagnosis. We present a new curiosity: a DF with intracytoplasmic eosinophilic globules. 相似文献
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Alexander Albrecht Benny Levenson Klaus -Dirk Henke J. -Matthias Graf von Schulenburg Alexander Albrecht Peter Bossiljanoff Benny Levenson Rolf Mertens Matthias Redecker Rainer Schräder Hans F. Spieß Kay Thierfelder Bernhard Bohlen Gerd Kleiber Michael Lehnert Gäste Wolfgang Stark Josef Fahn Helmut Heckenstaller Ernst Thiel 《Herz》1999,24(1):89-91
Ohne Zusammenfassung 相似文献
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Rudolf Gmür Carlo P. Marinello Bernhard Guggenheim 《European journal of oral sciences》1999,107(3):225-228
The purpose of this study was the clinical and microbiological re-examination of dental hygienists, who, 30 months before, had shown remarkably high supragingival levels of periodontitis-associated micro-organisms. Interdental plaque was collected from the same molar sites and investigated by the same immunofluorescence assay with taxa-specific monoclonal antibodies as at the initial examination. On average, the 15 re-examined subjects showed slightly increased plaque levels but unchanged bleeding on probing scores (0.3-1.4). Pocket formation was restricted to a single subject. Prevotella intermedia/P. nigrescens and Peptostreptococcus micros were present in every plaque sample. Prevalences of Actinobacillus actinomycetemcomitans, Bacteroides forsythus and Campylobacter rectus were again between 20-40%, but some fluctuation within subjects was noted. The data confirm supragingival plaque as a natural habitat for periodontitis-associated bacteria in periodontially healthy persons, and indicate that colonization with A. actinomycetemcomitans, B. forsythus or C. rectus is mostly stable in spite of better than average personal plaque control. 相似文献
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999.
Coronary collateral flow reversal 总被引:1,自引:0,他引:1
Summary Coronary collaterals demonstrated angiographically are expected to be usable both ways and to remain on standby even if they are no longer used after flow improvement through the physiological pathway. Evidence of these hypotheses is provided by two case reports, one showing spontaneous reversal of collaterals and one showing recruitable reversed collaterals. 相似文献
1000.
Clinical validation of a novel enzyme‐linked immunosorbent spot assay‐based in vitro diagnostic assay to monitor cytomegalovirus‐specific cell‐mediated immunity in kidney transplant recipients: a multicenter,longitudinal, prospective,observational study 下载免费PDF全文
Bernhard Banas Dominik Steubl Lutz Renders Dominik Chittka Miriam C. Banas Thomas Wekerle Martina Koch Oliver Witzke Anja Mühlfeld Claudia Sommerer Antje Habicht Christian Hugo Thomas Hünig Monika Lindemann Traudel Schmidt Anne Rascle Sascha Barabas Ludwig Deml Ralf Wagner Bernhard K. Krämer Bernd Krüger 《Transplant international》2018,31(4):436-450
Impaired cytomegalovirus (CMV)‐specific cell‐mediated immunity (CMV‐CMI) is a major cause of CMV reactivation and associated complications in solid‐organ transplantation. Reliably assessing CMV‐CMI is desirable to individually adjust antiviral and immunosuppressive therapy. This study aimed to evaluate the suitability of T‐Track® CMV, a novel IFN‐γ ELISpot assay based on the stimulation of peripheral blood mononuclear cells with pp65 and IE‐I CMV proteins, to monitor CMV‐CMI following kidney transplantation. A prospective longitudinal multicenter study was conducted in 86 intermediate‐risk renal transplant recipients. CMV‐CMI, CMV viral load, and clinical complications were monitored over 6 months post‐transplantation. Ninety‐five percent and 88–92% ELISpot assays were positive pre‐ and post‐transplantation, respectively. CMV‐specific response was reduced following immunosuppressive treatment and increased in patients with graft rejection, indicating the ability of the ELISpot assay to monitor patients' immunosuppressive state. Interestingly, median pp65‐specific response was ninefold higher in patients with self‐clearing viral load compared to antivirally treated patients prior to first viral load detection (P < 0.001), suggesting that reactivity to pp65 represents a potential immunocompetence marker. Altogether, T‐Track® CMV is a highly sensitive IFN‐γ ELISpot assay, suitable for the immunomonitoring of CMV‐seropositive renal transplant recipients, and with a potential use for the risk assessment of CMV‐related clinical complications (ClinicalTrials.gov Identifier: NCT02083042). 相似文献