The self-recovery of facial skin barrier and erythema after nanochip treatment

Objective: To determine the degree of acute skin damage and the time required for the recovery of facial skin barrier function after the skin was treated with micro-needles and nanochips of various tip lengths. Methods: For this split face comparative study, a total of 16 subjects were enrolled and randomly divided into 2 groups. In the first group, one of the facial side of each subject was treated with 0.25-mm long nanotips for a total of 6 times while the other facial side was treated with 0.25-mm traditional micro-needles with a straight blade for a total of 6 times. In the second group, one of the facial side was treated with 0.5-mm nanotips for a total of 6 times while the other facial side was treated with 0.5-mm traditional micro-needles with a straight blade for a total of 6 times. Evaluations for trans-epidermal water loss (TEWL), skin hydration and erythema were carried out at baseline, 0, 4, 8, 24, 48 and 72 hours after the treatment. Results: There was no significant difference in TEWL, skin hydration and erythema between the two facial sides of the subjects in the Group one who were treated with 0.25 mm nanochips and traditional micro-needles. However, in the subjects of the Group two, the mean TEWL of the facial side treated with 0.5 mm nanochips was relatively lower than that of the 0.5 mm traditional micro-needles treated facial side at 0, 4, 8 and 24 hours after the treatment. Mean erythema of the facial side treated with 0.5-mm nanochips micro-needles was also relatively lower than that of the 0.5-mm traditional micro-needles treated facial side at 8 hours after the treatment. Rapid recovery of skin barrier function was observed within 4–8 hours after treatment with various lengths of nanochips while it took at least 48–72 hours for recovery of skin barrier function after treatment with various lengths of traditional micro-needles as measured by TEWL. Conclusion: The skin disruption caused by nanotips treatment recovers quicker than the traditional microneedle treatment at equal lengths.     

Effect of menthol on ocular drug delivery

Background  

To assess how safe and effective it is to use menthol as a permeability enhancer in ophthalmic drug delivery systems.     

高压氧治疗脑外伤病人的效果观察

高压氧治疗是指周期性呼吸超过一个大气压纯氧的治疗.高压氧可提高血氧含量和血氧弥散度,从而改善脑组织的缺氧,使脑组织氧分压相应提高,同时高压氧又可使脑组织线粒体中H+-ATP酶活性增加,从而促进脑组织的修复[1].     

探讨子宫内膜病变的诊断与治疗

目的 探讨子宫内膜病变诊断与治疗以及妇女病筛查的重要性;方法对158例有症状绝经妇女进行超声检查,并行诊断性刮宫,内膜送病理检查,分析其中的阳性符合率,以期超声作为绝经妇女内膜癌的主要筛查手段;结论超声是经济、实用、无痛、无创、快捷的子宫内膜病变筛查的可靠检查方法,对临床诊疗有重要的指导意义.     

36例人工心脏起搏器置入后并发症的观察与护理

[目的]总结人工心脏起搏器置入后并发症的观察与护理措施。[方法]回顾性分析36例人工心脏起搏器置入后发生并发症的临床资料。[结果]本组除1例皮肤过敏致溃烂病人愈合欠佳外,其余均未发生严重后果,康复出院。[结论]加强人工心脏起搏器置入后并发症的观察与护理有利于预后。     

实施6S管理模式提高血液透析室护理工作质量

随着医学科学技术的飞速发展,现代护理管理模式正经历着变革.6S管理是一种先进的管理模式,它的核心和精髓是素养.如果没有员工队伍素质的相应提高,6S管理就难以开展和坚持下去,而人员素质的提升是医院可持续发展的本质.孝感市中心医院血液透析室实行以整理、整顿、清洁、规范、素养、安全为主要内容的6S管理,全科医护人员积极广泛参与,有计划、有步骤、全方位在各领域逐渐落实6S管理,有效提高了血液透析室的工作质量.     

浅析军队疗养员在疗养期间易产生的心理问题及对策

<正>随着医疗模式从单纯生物医学模式向生物-社会-心理医学模式的转变,人们越来越重视心理因素在疾病发生、发展及治疗过程中的作用,也积极探索促进心理健康的各种方法。军队疗养院作为一个医疗卫生保健单位,担负着"平时保健康,战时保打赢"的重要职责。