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排序方式: 共有210条查询结果,搜索用时 15 毫秒
81.
Alireza Heydari Mohammad Tayyebi Rahmatolah Damanpak Jami Asgar Amiri 《Texas Heart Institute journal / from the Texas Heart Institute of St. Luke's Episcopal Hospital, Texas Children's Hospital》2014,41(3):280-285
Noninducibility of the arrhythmia is the widely accepted endpoint of successful ablation of atrioventricular nodal reentrant tachycardia (AVNRT). However, to rely upon that as the only endpoint, the arrhythmia must also be inducible before ablation. Despite the fact that AVNRT is not reproducibly inducible in a significant number of cases, the role of reproducible arrhythmia induction and its relationship with the infusion of isoproterenol after successful ablation of AVNRT has not been well defined.We studied 175 consecutive patients who all underwent successful radiofrequency ablation after showing that they had reproducibly inducible AVNRT without use of isoproterenol. In Group 1 (n=90), isoproterenol was used for arrhythmia reinduction after ablation, whereas in Group 2 (n=85) it was not. The procedural and follow-up data of both groups were recorded, and the results of appropriate statistical tests were analyzed.During a mean follow-up time of 18.7 ± 4.5 months, 4 patients in Group 1 and 3 patients in Group 2 experienced recurrences. Regardless of elimination or modification of slow-pathway conduction, no significant difference was seen in the recurrence rates of AVNRT between the 2 groups (P=0.72).We conclude that, when the original arrhythmia in patients with AVNRT is reproducibly inducible in the basal state, the use of isoproterenol after ablation in order to confirm the noninducibility of AVNRT does not appear to alter the recurrence rates and can be omitted. 相似文献
82.
Xavier Freixa MD Patrick Garceau MD Anita W. Asgar MD 《Catheterization and cardiovascular interventions》2013,81(7):1238-1242
Transcatheter closure of an atrial septal defect (ASD) is considered the standard of care for most of the patients with secundum ASD. The existence of multiple or fenestrated ASD may constitute a challenge to achieve a satisfactory result. Data on the usage of multiple devices for closing multiple defects are limited. The GORE® Septal Occluder (GSO) represents a new generation of transcatheter ASD occluders with a design that provides superior conformability, apposition, and closure performance compared with the previous GORE® HELEX device. The present case report describes the first clinical experience with the implantation of two GSO devices in a patient with multiple ASDs and fenestrated septum. © 2012 Wiley Periodicals, Inc. 相似文献
83.
Ahad A Aqil M Kohli K Sultana Y Mujeeb M Ali A 《Nanomedicine : nanotechnology, biology, and medicine》2012,8(2):237-249
The purpose of this work was to develop and statistically optimize nanotransfersomes for enhanced transdermal of valsartan vis-à-vis traditional liposomes. Nanotransfersomes bearing valsartan were prepared by conventional rotary evaporation method and characterized for various parameters including entrapment efficiency, vesicles shape, size, size distribution, and skin permeation. In vivo antihypertensive activity conducted on Wistar rats was also taken as a measure of performance of nanotransfersomes and liposomes. Nanotransfersomes proved significantly superior in terms of amount of drug permeated in the skin, with an enhancement ratio of 33.97 ± 1.25 when compared to rigid liposomes. This was further confirmed through a confocal laser scanning microscopy study. Nanotransfersomes showed better antihypertensive activity in comparison to liposomes by virtue of better permeation through Wistar rat skin. Finally, it could be concluded that the nanotransfersomes accentuates the transdermal flux of valsartan and could be used as a carrier for effective transdermal delivery of valsartan. FROM THE CLINICAL EDITOR: In this paper, the authors discuss the development and optimization of nanotransfersomes for enhanced transdermal of valsartan and demonstrate accentuated transdermal compared to standard preparations. 相似文献
84.
Ergin A Syrbe U Scheer R Thiel A Adam T Büssow K Duchmann R Zeitz M Sieper J 《Journal of clinical immunology》2011,31(6):998-1009
Background
To clarify the impact of T cell responses towards enteric antigens for chronic intestinal inflammation, we determined T helper 1 reactivity towards conserved Escherichia coli proteins in patients with Crohn’s disease (CD) and healthy individuals and patients with ankylosing spondylitis (AS), who also often show microscopic inflammatory lesions within the gut or even develop overt inflammatory bowel disease. 相似文献85.
Mohammad Ali Saghiri Abbas Delvarani Payman Mehrvarzfar Mohsen Nikoo Mehrdad Lotfi Kasra Karamifar Kamal Asgar Sahar Dadvand 《Saudi Dental Journal》2011,23(3):149-152
Aim
Cytotoxicity of root canal irrigants is important due to their close contact with host tissues. This study was to assess the possible impact of pH on cytotoxic effects of MTAD, 17% EDTA, and 2.6% NaOCl on the human gingival fibroblasts using MTT assay.Materials and methods
Human gingival fibroblasts were exposed to the irrigants and their viability was assessed after 1, 6, and 12 h. The pH of the medium was measured in each interval. Light absorption values were measured for each culture medium using Elisa Reader device.Results
NaOCl had significantly less cytotoxicity than EDTA and MTAD. Also irrigants cytotoxicity decreased in 12, 1, and 6 h, respectively.Conclusion
It seems that variation of the pH resulted in variation in the cytotoxicity of solutions; i.e., it follows the pattern of the pH variation. 相似文献86.
Le Gloan L Mercier LA Dore A Marcotte F Mongeon FP Ibrahim R Asgar A Poirier N Khairy P 《Expert review of cardiovascular therapy》2011,9(12):1547-1556
Advances in the care of patients with a univentricular heart have enabled the majority to survive well into adulthood. Consequently, an increasing number of women with Fontan palliation are contemplating pregnancy. This review summarizes physiologic modifications related to pregnancy in the setting of single-ventricle physiology, discusses potential maternal cardiovascular concerns and describes commonly encountered obstetrical and neonatal complications. Management issues are addressed, including counseling, anesthetic considerations and the need for multidisciplinary specialized care. 相似文献
87.
David Power Ulrich Schfer Paul Guedeney Bimmer E. Claessen Samantha Sartori Sabato Sorrentino Thierry Lefvre Christian Kupatt Didier Tchetche Nicolas Dumonteil John G. Webb Antonio Colombo Stephen Windecker Jurriën M. ten Berg David Hildick‐Smith Peter Boekstegers Axel Linke Christophe Tron Eric Van Belle Anita W. Asgar Raban Jeger Gennaro Sardella Ulrich Hink Oliver Husser Eberhard Grube Ilknur Lechthaler Peter Wijngaard Prodromos Anthopoulos Efthymios N. Deliargyris Debra Bernstein Christian Hengstenberg Roxana Mehran George D. Dangas 《Catheterization and cardiovascular interventions》2019,93(7):1374-1381
88.
Alam MS Ali A Mehdi SJ Alyasiri NS Kazim Z Batra S Mandal AK Rizvi MM 《Tumour biology》2012,33(1):17-22
Definite progress in understanding the etiology of cervical cancer has been achieved, and some types of human papillomavirus
have been established as the central cause of cervical cancer worldwide. This study investigates the human papillomavirus
infection and its correlation with apoptosis and clinicopathologic characteristics in squamous cell carcinoma of uterine cervix.
Human papillomavirus typing was done by type-specific primers for high-risk human papillomavirus using standard polymerase
chain reaction method. Programmed cell death (apoptosis) was determined by terminal deoxynucleotidyl transferase biotin–dUTP
nick end labeling assay. Human papillomavirus infection in tissue biopsy of cervical carcinoma was detected in 131 of 135
(97%) cases. Among the positive cases of human papillomavirus, 123 (94%) cases were human papillomavirus type 16, and five
(4%) cases were human papillomavirus type 18. Out of 135 cervical carcinoma cases, 81 (60%) cases showed presence of apoptosis.
The phenomenon of apoptosis was seen slightly higher in squamous cell carcinoma than in adenocarcinoma (40% in squamous cell
carcinoma and 33% in adenocarcinoma). The human papillomavirus infection in cervical cancer might not play any role in the
occurrence of apoptosis. 相似文献
89.
Anita W Asgar Joaquim Mirò Reda Ibrahim 《Catheterization and cardiovascular interventions》2007,70(4):591-594
Complete transposition of the great arteries has been historically managed by the Mustard (atrial switch) operation. This procedure is associated with longterm complications such as baffle occlusion, which also precludes the insertion of a permanent transvenous pacemaker. Transcatheter techniques have allowed the successful angioplasty and stenting of stenotic baffles but complete occlusions continue to pose a therapeutic challenge. We report the use of a novel technique, a radiofrequency perforation wire for the management of complete occlusion of systemic venous baffles post-Mustard operation. 相似文献
90.
Clinical Rheumatology - The rise in non-communicable diseases in Africa presents challenges for health systems that are burdened by infectious diseases. Gout is one of those diseases that has seen... 相似文献