全文获取类型
收费全文 | 110504篇 |
免费 | 7442篇 |
国内免费 | 1275篇 |
专业分类
耳鼻咽喉 | 968篇 |
儿科学 | 3264篇 |
妇产科学 | 2981篇 |
基础医学 | 14353篇 |
口腔科学 | 1959篇 |
临床医学 | 10029篇 |
内科学 | 25573篇 |
皮肤病学 | 2084篇 |
神经病学 | 11307篇 |
特种医学 | 3408篇 |
外国民族医学 | 2篇 |
外科学 | 12488篇 |
综合类 | 2414篇 |
现状与发展 | 2篇 |
一般理论 | 45篇 |
预防医学 | 7688篇 |
眼科学 | 1710篇 |
药学 | 8610篇 |
8篇 | |
中国医学 | 1104篇 |
肿瘤学 | 9224篇 |
出版年
2023年 | 1094篇 |
2022年 | 2216篇 |
2021年 | 4432篇 |
2020年 | 2674篇 |
2019年 | 3214篇 |
2018年 | 3614篇 |
2017年 | 2890篇 |
2016年 | 3152篇 |
2015年 | 3651篇 |
2014年 | 4774篇 |
2013年 | 5936篇 |
2012年 | 8370篇 |
2011年 | 8412篇 |
2010年 | 4682篇 |
2009年 | 4142篇 |
2008年 | 6628篇 |
2007年 | 6703篇 |
2006年 | 6140篇 |
2005年 | 5671篇 |
2004年 | 5225篇 |
2003年 | 4600篇 |
2002年 | 4124篇 |
2001年 | 1764篇 |
2000年 | 1626篇 |
1999年 | 1600篇 |
1998年 | 895篇 |
1997年 | 702篇 |
1996年 | 620篇 |
1995年 | 531篇 |
1994年 | 482篇 |
1993年 | 401篇 |
1992年 | 827篇 |
1991年 | 714篇 |
1990年 | 635篇 |
1989年 | 653篇 |
1988年 | 560篇 |
1987年 | 513篇 |
1986年 | 492篇 |
1985年 | 393篇 |
1984年 | 374篇 |
1983年 | 297篇 |
1982年 | 215篇 |
1981年 | 175篇 |
1980年 | 157篇 |
1979年 | 242篇 |
1978年 | 164篇 |
1977年 | 146篇 |
1974年 | 146篇 |
1973年 | 146篇 |
1972年 | 139篇 |
排序方式: 共有10000条查询结果,搜索用时 625 毫秒
21.
22.
23.
Alessia Scarselli Silvia Di Cesare Claudia Capponi Simona Cascioli Maria L. Romiti Gigliola Di Matteo Alessandra Simonetti Paolo Palma Andrea Finocchi Barbarella Lucarelli Rita M. Pinto Ippolita Rana Giuseppe Palumbo Maurizio Caniglia Paolo Rossi Rita Carsetti Caterina Cancrini Alessandro Aiuti 《Journal of clinical immunology》2015,35(4):373-383
24.
25.
26.
27.
AbstractAim: Competency-based medical education aims to foster mastery goals in learners. We examined medical students’ mastery approach (beneficial) and mastery avoidance (maladaptive) goals and their associations with students’ basic psychological needs, self-compassion, and self-efficacy.Methods: This was a cross-sectional study employing an online questionnaire. Two hundred medical students in all four years of the medical program completed the questionnaire, containing measures of mastery goals, basic psychological needs (autonomy, competence, relatedness), self-compassion, and self-efficacy. Regression analyses were performed.Results: Of the three basic psychological needs, the need for competence was significant in explaining both types of mastery goals. Self-efficacy and self-compassion were significant in explaining mastery approach and mastery avoidance goals, respectively.Conclusions: Creating learning environments that are supportive of students’ need for competence, raising students’ awareness of the value of learning from mistakes in competency acquisition, and providing opportunities for students to experience self-efficacy may foster beneficial mastery approach goals in medical students. 相似文献
28.
Erika Cecon Anna Ivanova Marine Luka Florence Gbahou Anne Friederich Jean‐Luc Guillaume Patrick Keller Klaus Knoch Raise Ahmad Philippe Delagrange Michele Solimena Ralf Jockers 《Journal of pineal research》2019,66(2)
Melatonin receptors play important roles in the regulation of circadian and seasonal rhythms, sleep, retinal functions, the immune system, depression, and type 2 diabetes development. Melatonin receptors are approved drug targets for insomnia, non‐24‐hour sleep‐wake disorders, and major depressive disorders. In mammals, two melatonin receptors (MTRs) exist, MT1 and MT2, belonging to the G protein‐coupled receptor (GPCR) superfamily. Similar to most other GPCRs, reliable antibodies recognizing melatonin receptors proved to be difficult to obtain. Here, we describe the development of the first monoclonal antibodies (mABs) for mouse MT1 and MT2. Purified antibodies were extensively characterized for specific reactivity with mouse, rat, and human MT1 and MT2 by Western blot, immunoprecipitation, immunofluorescence, and proximity ligation assay. Several mABs were specific for either mouse MT1 or MT2. None of the mABs cross‐reacted with rat MTRs, and some were able to react with human MTRs. The specificity of the selected mABs was validated by immunofluorescence microscopy in three established locations (retina, suprachiasmatic nuclei, pituitary gland) for MTR expression in mice using MTR‐KO mice as control. MT2 expression was not detected in mouse insulinoma MIN6 cells or pancreatic beta‐cells. Collectively, we report the first monoclonal antibodies recognizing recombinant and native mouse melatonin receptors that will be valuable tools for future studies. 相似文献
29.
30.
A. Cattapan K. Browne D.M. Halperin A. Di Castri P. Fullsack J. Graham J.M. Langley B.A. Taylor S.A. McNeil S.A. Halperin 《Vaccine》2019,37(2):289-295