全文获取类型
收费全文 | 1339341篇 |
免费 | 96502篇 |
国内免费 | 3312篇 |
专业分类
耳鼻咽喉 | 19746篇 |
儿科学 | 40273篇 |
妇产科学 | 38732篇 |
基础医学 | 187824篇 |
口腔科学 | 39939篇 |
临床医学 | 113187篇 |
内科学 | 262942篇 |
皮肤病学 | 30336篇 |
神经病学 | 106595篇 |
特种医学 | 53940篇 |
外国民族医学 | 436篇 |
外科学 | 208632篇 |
综合类 | 32146篇 |
现状与发展 | 7篇 |
一般理论 | 436篇 |
预防医学 | 92491篇 |
眼科学 | 31512篇 |
药学 | 100624篇 |
7篇 | |
中国医学 | 3340篇 |
肿瘤学 | 76010篇 |
出版年
2018年 | 11966篇 |
2015年 | 12123篇 |
2014年 | 17022篇 |
2013年 | 25550篇 |
2012年 | 33417篇 |
2011年 | 35282篇 |
2010年 | 21024篇 |
2009年 | 20463篇 |
2008年 | 33883篇 |
2007年 | 37073篇 |
2006年 | 37586篇 |
2005年 | 36277篇 |
2004年 | 35482篇 |
2003年 | 34530篇 |
2002年 | 33993篇 |
2001年 | 63933篇 |
2000年 | 65513篇 |
1999年 | 55490篇 |
1998年 | 14705篇 |
1997年 | 13522篇 |
1996年 | 12983篇 |
1995年 | 12263篇 |
1994年 | 11487篇 |
1992年 | 42775篇 |
1991年 | 41296篇 |
1990年 | 40565篇 |
1989年 | 39564篇 |
1988年 | 36966篇 |
1987年 | 36418篇 |
1986年 | 34905篇 |
1985年 | 33110篇 |
1984年 | 24825篇 |
1983年 | 21057篇 |
1982年 | 12666篇 |
1981年 | 11570篇 |
1980年 | 10773篇 |
1979年 | 23925篇 |
1978年 | 17069篇 |
1977年 | 14834篇 |
1976年 | 13388篇 |
1975年 | 15268篇 |
1974年 | 18080篇 |
1973年 | 17560篇 |
1972年 | 16806篇 |
1971年 | 15694篇 |
1970年 | 14874篇 |
1969年 | 14321篇 |
1968年 | 13441篇 |
1967年 | 11994篇 |
1966年 | 11242篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
151.
Saisanjana Kalagara Adam E.M. Eltorai J. Mason DePasse Alan H. Daniels 《The spine journal》2019,19(1):182-185
BACKGROUND
Online physician rating websites are increasingly used by patients to evaluate their doctors. The purpose of this investigation was to evaluate factors associated with better spine surgeon ratings.METHODS
Orthopedic spine surgeons were randomly selected from the North American Spine Society directory utilizing a random number generator. Surgeon profiles on three physician rating websites, namely, www.HealthGrades.com, www.Vitals.com, and www.RateMDs.com, were analyzed to gather qualitative and quantitative data on patients’ perceptions of the surgeons. Independent variables from the websites were analyzed in relation to overall physician or patient satisfaction rating. Comments were coded by subject into following three categories: professional competence, bedside manner, and practice characteristics.RESULTS
A total of 250 surgeons were evaluated, and 92% (n=230) of these doctors had at least one rating among the three websites. The surgeons with a higher average rating had significantly better trust (p<.01), scheduling (p<.01), staff (p<.01), helpfulness (p<.01), and punctuality (p<.01) scores but significantly less experience (p<.05). A linear regression model for the average rating of each surgeon (R2 value=0.754) yielded only following three significant variables: trustworthiness (p<.01), experience match (p<.05), and the average number of negative comments on surgeon's professional competence (p<.05). Trustworthiness (β=0.749) was the strongest predictor variable of physician rating, followed by the number of negative professional competence comments (β=?0.132) and experience match (β=?0.112).CONCLUSIONS
This investigation assessed spine surgeon online patient ratings and categorized factors that patients associate with quality care. Trustworthiness was the most significant predictor of positive ratings, whereas ease of scheduling, quality of staff, helpfulness, and punctuality were also associated with higher patient ratings. Understanding what patients value may help optimize care of spine surgery patients. 相似文献152.
B. Davido R. Batista H. Fessi H. Michelon L. Escaut C. Lawrence M. Denis C. Perronne J. Salomon A. Dinh 《Médecine et maladies infectieuses》2019,49(3):214-218
Objective
A rapid and worrying emergence of vancomycin-resistant enterococci (VRE) gut colonization is occurring worldwide and may be responsible for outbreaks, especially in healthcare facilities. While no efficient decolonization strategies are recommended, we assessed fecal microbiota transplantation (FMT) to eradicate VRE colonization.Patients and method
Our main objective was to measure the impact of FMT on decolonization of VRE carriers, confirmed by at least two consecutive negative rectal swabs at one-week interval during a 3-month follow-up period. Patients received no antibiotic prior to the FMT.Results
After a month only three patients remained colonized with VRE. Decolonization was associated with 87.5% (n = 7) of success after three months as only one patient remained colonized.Conclusion
Our first results confirm that the FMT seems to be safe, with an impact on VRE colonization over time that may help control outbreaks. 相似文献153.
154.
155.
156.
157.
158.
Cécile Vicier Lillian Werner Jonathan Chipman Lauren C. Harshman Dattatraya H. Patil Raina N. Fichorova Jennifer R. Rider Martin G. Sanda Lorelei A. Mucci Christopher J. Sweeney 《Clinical genitourinary cancer》2019,17(1):32-37
Background
Inflammation and infections have been associated with prostate cancer progression. We assessed whether elevated serum cytokines or T. vaginalis seropositivity at the time of diagnosis was associated with higher grade or lethal prostate cancer.Patients and Methods
Men with localized or metastatic prostate cancer were included in this study. Cytokine serum levels including interleukin (IL)-1α, IL-1β, IL-2, IL-6, IL-8, monocyte chemotactic protein 1 (CCL-2), tumor necrosis factor α, and growth-regulated oncogene α (CXCL-1) using a multiplex enzyme-linked immunosorbent assay and T. vaginalis serology were measured in blood samples at diagnosis.Results
A total of 324 patients were identified at time of localized disease and 118 at time of metastatic disease. Of the 189 patients with localized disease and clinical follow-up data (median, 73 months), 28 developed lethal disease. There was no association between circulating cytokine levels above median concentrations nor T. vaginalis seropositivity and risk of intermediate- to high-risk or lethal prostate cancer.Conclusion
Higher levels of serum cytokine levels and T. vaginalis seropositivity at diagnosis are not associated with high-grade or lethal prostate cancer and do not aid risk stratification of localized prostate cancer. 相似文献159.
C. Jacquet F. Goehringer E. Baux J.A. Conrad M.O. Ganne Devonec J.L. Schmutz G. Mathey H. Tronel T. Moulinet I. Chary-Valckenaere T. May C. Rabaud 《Médecine et maladies infectieuses》2019,49(2):112-120
Objective
The teaching hospital of Nancy, France, implemented a specific multidisciplinary care pathway (French acronym AMDPL) to improve the management of patients presenting with Lyme borreliosis (LB) suspicion. We aimed to assess the first year of activity of this care pathway.Patients and methods
We included all patients managed in the AMDPL pathway from November 1, 2016 to October 31, 2017. The first step was a dedicated Lyme disease consultation with an infectious disease specialist. Following this consultation, the LB diagnosis was either confirmed and adequate treatment was prescribed, or a differential diagnosis was established and patients received adequate management, or further investigations were required and patients were offered multidisciplinary management as part of a day hospitalization.Results
A total of 468 patients were included. LB diagnosis was confirmed in 15% of patients (69/468), 49% of patients received a differential diagnosis, and 26% (122/468) of patients had the LB diagnosis ruled out without receiving any other diagnosis.Conclusions
This is to our knowledge the first multidisciplinary center implemented in France for the management of patients presenting with LB suspicion related to polymorphous signs and symptoms. Several diagnoses could be confirmed or corrected, although some symptoms and complaints could not be explained. This cohort could improve our knowledge of LB and its differential diagnoses. 相似文献160.