胸腺类癌6例

我院1980年1月至2004年5月共收治6例胸腺类癌，现报道如下。     

表达端粒酶逆转录酶siRNA的溶瘤腺病毒对裸鼠肾癌移植瘤的治疗作用

Objective To investigate the antitumor effect of oncolytic adenovirus armed with small interference RNA targeting hTERT gene for renal cancer therapy. Methods Nude mice were divid-ed randomly into 4 groups (8 mice/group),and were treated by intratumoral injections of ZD55-hTERT ( an oncolytic adenovirus armed with small interference RNA targeting hTERT gene) ,ZD55-EGFP ( an on-colytic adenovirus) and Ad-hTERT (replication-defective adenovirus armed with small interference RNA targeting hTERT gene) with three consecutive daily at 7 × 108 pfu/day or treated with PBS as a control. The expression of E1A and hTERT, and apoptosis of tumor xenografts were assessed by immunohistochemi-cal technique at the 7th day after injections. The tumor volume was measured at the 50th day after injec-tions. Results The tumor volume in ZD55-hTERT treatment group ( 124.1±27.5) was significantly less than that in ZD-EGFP (499.8±77.1 ) and Ad-hTERT ( 609.0±102.5 ) treatment groups. The E 1A pos-itive expression in ZD55-hTERT treatment group was significantly higher than that in Ad-hTERT treatment group. The hTERT positive expression in ZD55-hTERT treatment group was significantly lower than that in Ad-hTERT treatment group. ZD55-hTERT treatment of tumor xenografts resulted in an increased apoptotie cell death as compared with ZD55-EGFP and Ad-hTERT treatment. Conclusion The antitumor effect of ZD55-hTERT was more potent than oneolytie adenovirus ZD55-EGFP and Ad-hTERT.     

异位恶性脉络丛乳头状瘤三例报告

例1,女,48岁,头痛半年伴呕吐1月余于1986年6月10日入院。查:神清,双侧视乳头水肿,余未见明显神经系统定位征。CT示:左顶后5cm×4cm×4cm类园形病灶,周边为稍高密度环,中央为等密度及低密度,CT值49HU,增强后为不规则环状及结节状强化。周围大片水肿区。考     

成人非梗阻性巨十二指肠--附2例报告及文献复习

目的：探讨成人非梗阻性巨十二指肠的临床、影像特点和诊断方法。方法：报告2例成人巨十二指肠临床、影像检查资料和对有关献进行回顾性复习。结果：2例均为男性，年龄分别为25岁和41岁，经上消化道气钡双重造影及胃十二指肠镜检查证实，为十二指肠降部显扩张，远端无狭窄。结论：成人非梗阻性巨十二指肠是一种特发性的先天畸形，临床可无明显症状。继发性的以十二指肠隔膜症多见。X线检查表现特殊具有重要价值。     

气功也能治疗急病实证

气功也能治疗急病实证湖南省永兴县文化馆易高超中医学上的八纲辨证之中，有虚实两纲，主要是判断病邪的盛衰与人体抗病能力的强弱。虚，指正气不足；实，指邪气有余。例如胃病，由于病人气虚体弱，长期患慢性胃炎、胃溃疡等，此为虚证。由于吃过量难于消化的食物；或者吃...     

三脑室前部病灶手术入路选择

三脑室前部肿瘤包括原发性和继发性肿瘤:前者起源于三脑室壁,后者起源于三脑室邻近结构。该区域毗邻视神经、视交叉、视束、下丘脑-垂体系、Willi's环及其穿支动脉和大脑深部引流静脉,此外还与诸多记忆功能相关结构毗邻,如丘脑、乳头体、乳头丘脑束、穹隆和内髓板,手术难度及风险均较高。神经内镜在治疗三脑室囊性病变,具有明显优势。目前应用较为广泛的手术方式包括经终板入路、经额叶皮层入路和经胼胝体入路。     

小议外守远目标

小议外守远目标易高超气功界有一句俗语：“气功非气功，全在意念中。”这说明气功与意念如同鱼和水的关系一样，十分密切。如果气功离开了意念，也就不成其为气功了。意念的运用有内守与外守之分，现在来议论一下外守远目标的选择，对我们学练气功、研究气功大有益处。外...     

消痔灵治疗内痔5240例

<正> 治疗方法:患者取侧卧位,常规消毒,铺无菌巾,局麻或不用麻醉。在嗽叭型肛门镜直视下用0.1‰的新洁尔灭消毒痔区,取10毫升注射器用5号针头吸取消痔灵稀释液四步注射。(广安门医院注射法)。1.直肠上动脉区:用稀释液1:1的浓度(消痔灵1毫升,1%盐酸普鲁卡因1毫升)刺入痔核上端0.5厘米处,深约粘膜下3～5毫米,抽无回血后,注药3～5毫升。2.痔区粘膜下层:用2:1的浓度(消痔灵1毫升,1%盐酸普鲁卡因2毫升),在痔中部进针至粘膜下层,行扇行注射,使药液均匀地充盈到粘膜下层中,痔核呈弥漫水泡状肿胀为宜,每痔核注药4～8毫升。3.粘膜固有层:当第二步注射完毕后,缓慢退针,