平板运动试验多变量分析法对冠心病的诊断价值探讨

近年来,国外一些学者对心电图运动试验不是仅以ST段的改变而是用多变量分析法进行判断,并认为心率、血压、ST段、R波振幅、运动时间以及运动心绞痛等均为检测冠心病的有价值的变量。为了估计运动各变量及多变量分析法对冠心病的诊断意义,我们对比分析了32例正常人和31例冠心病人平板运动试验中上述变量的改变,并比较了ST段标准与多变量分析法的临床诊断价值。     

鼻窦镜辅助下经单鼻孔蝶窦入路显微切除垂体腺瘤

目的研究在鼻窦镜与手术显微镜配合行经单鼻孔-蝶窦入路切除垂体腺瘤手术的临床价值。方法垂体腺瘤70例均行经口气管插管静脉复合全身麻醉后,用直径4mm的0°和30°硬性鼻窦镜及配套摄像系统,配合手术显微镜行经单鼻孔-蝶窦入路垂体腺瘤切除术。结果 70例垂体腺瘤中,59例一次手术全切除,5例分2次手术全切除,6例次全切除。术后患者临床症状均有改善。术后随访1～3年,64例肿瘤全切除者无肿瘤复发,6例次全切除者术后行伽玛刀治疗,残余肿瘤均无明显增大。结论鼻窦镜与手术显微镜配合应用,各有优缺点,能扬长避短,对于提高单鼻孔-蝶窦入路手术疗效、减少副损伤及提高手术安全性具有重要的临床价值。     

散结饮加电针足三里对腹部术后胃肠功能恢复的影响

2005年1~5月,我们对80例腹部手术患者行散结饮加电针足三里治疗,术后肠鸣音恢复和排气、排便时间明显缩短,腹胀和下肢静脉血栓发生率明显减少。现报告如下。临床资料:本文治疗组80例,男51例、女29例,年龄19~86(38.0±9.4)岁,行胃肠手术32例,肝胆手术28例,脾胰手术20例;对照组40例,男27例、女13例,年龄18~84(37.0±9.8)岁,行胃肠手术19例,肝胆手术13例,脾胰手术8例。两组性别、年龄、病情、手术方式等差异无统计学意义。方法:对照组术后常规给予禁食、静脉输液、补充电解质、维生素、抗生素及静脉或肠内营养等。治疗组在上述治疗基础上,术后6…     

磷脂酶Cγ的分子生物学研究进展

磷脂酶Cγ(PLCγ)是磷脂酶C(PLC)的一种,而磷脂酶C又是磷脂酰肌醇信号通路的关键酶,在机体内分布极为广泛.许多细胞外因子,如细胞表面抗原、免疫球蛋白、细胞因子、生长因子等都可以借助PLC的生化途径激活磷脂酰肌醇特异性途径作用于细胞,调控细胞代谢.PLCγ在B淋巴细胞的整个发育过程以及在其他生命活动中都起着重要的作用.     

原发性体液免疫缺陷病基因的分子生物学研究进展

原发性体液免疫缺陷病是原发性免疫缺陷病中常见的一类疾病,其并发症严重威胁患儿健康.近年来,原发性体液免疫缺陷病逐渐受到医学界的重视,对原发性体液免疫缺陷病的研究取得了一些重要进展,特别是遗传学及分子生物学方面.研究原发性体液免疫缺陷病的基因情况,对指导临床的诊断、治疗均有积极意义.     

QRS综合波终末部分在心电图诊断下壁心肌梗塞中的重要性

传统上,诊断心肌梗塞的心电图标准均强调相应导联QRS综占波初始部分的异常,忽视了其终未郭分的诊断价值。作者对64例下壁心肌梗塞(IMI)患者和87例正常人的心电图进行定量分析后发现,IMI患者除Ⅱ、ⅢavF导联有不同程度的Q波外,还出现宽的终未R波。本文探讨这种宽的终末R波单独与传统的Q波标准联用时Ⅱ的对M     

分化型甲状腺癌行简化甲状腺癌改良根治术的合理性及临床应用

Objective To explore rationale and clinical application of simplified modified radical thyroideetomy for differentiated thyroid carcinoma.Methods From Jan.2007 to Jun.2010,349 cases of differentiated thyroid carcinoma received simplified operative procedure based on standard modified radical thyroidectomy.The simplified procedure took a low small collar incision(about 10-12 cm).In separating upper and lower skin flaps,subcutaneous tissues covering posterior triangle of neck and posterior edge of sternoeleidomastoid muscle were spared to protect sensory nerves.Subtotal thyroidectomy Was performed to resect the affected lobe,isthmus,and the majority of opposite lobe without considering the size of primary tumor or whether metastasis to the neck lymph nodes happened.Soft tissues of the mainly metastatic areas(Ⅱ a、Ⅲ、Ⅳ、Ⅴb)were cleared.The accessory nerve was not exposed routinely to avoid stimulation.Lymph nodes metastasis in different areas was recorded respectively.Complications in different operative modes were compared.Results Compared with standard modified radical thyroidectomy,the simplified mode had shorter scar-and no limit of neck mobility.Because of muscles and nerves pemervation,movement dysfunction and abnormal sensation of neck and shoulder decreased obviously.The operation duration was shortened.Cervical lymph node status Was evaluated,which provided basis for prognosis judgment and comprehensive treatment.Conclusions The simplified modified radical procedure has the benefit of decreased trauma while maintains the similar recurrence rate compared to modified radical thyroidectomy.It improvs the life quality of patients.This procedure fits the principle of functional radical neck dissection better.     

~(99m)Tc—热变性红细胞扫描在脾移植中的应用

本文报道~(99)mTc—热变性红细胞脾扫描能较好地反映移植脾的存活、功能、形态、大小和生长情况,并有无损伤、安全等优点