Effect of Captopril on Membrane Currents of Ventricular Myocytes

ＥｆｆｅｃｔｏｆＣａｐｔｏｐｒｉｌｏｎＭｅｍｂｒａｎｅＣｕｒｒｅｎｔｓｏｆＶｅｎｔｒｉｃｕｌａｒＭｙｏｃｙｔｅｓＷＡＮＧＹａｎｇ－ｇａｎ（王扬淦）；ＬＵＺａｉ－ｙｉｎｇ（陆再英）（ＤｅｐａｒｔｍｅｎｔｏｆＣａｒｄｉｏｌｏｇｙ，ＴｏｎｇｊｉＨｏｓｐｉｔ...     

抗心律失常药物对恶性室性快速心律失常疗效的预报因子

平均年龄59岁的94(男66、女28)例致命性心律失常患者经平均2.9种抗心律失常药物治疗无效(血     

冷刺激后无症状性心肌缺血

受试者为平均59.5(39～76)岁的35例冠心病患者,均有典型的稳定型心绞痛而且症状限制性活动平板试验阳性。另以8例健康志愿者和2例虽有胸痛但冠状动脉造影正常而且麦角新碱激发试验阴性者作为对照。采用~(82)铷作正电子发射计算机断层(PECT),分析左室中部层面(包括左室和后壁游离壁,室间隔的2个节段)上局部心肌灌注状况。以对照者检查结果为正常范围,凡是冷刺激或运动后阳离子摄取不均匀和/或局部阳离子摄取量减少(至 <对照者均值-2倍标准差),为PECT异常。     

Experimental Study of the Effect of Autonomic Nervous System on the Transmural Dispersion of Ventricular Repolarization under Acute Myocardial Ischemia in Vivo

The electrophysiologic heterogeneity of the ven-tricular myocardium is an important factor of devel-oping ventricular arrhythmia.Under the pathologiccondition,thedistribution and thefunction of the au-tonomic nerves,especially the sympathetic nerve,can produce the heterogeneity in the myocardium,which can accelerate the electrophysiologic hetero-geneity of the ventricular myocardium.Acute my-ocardial ischemia can induce the dysfunction of theautonomic nerve endings,resulting in the hetero-gene…     

β受体阻滞剂对在体犬跨室壁复极离散度影响的研究

用单相动作电位记录技术 ,在应用β受体阻滞剂前、后刺激交感神经过程中 ,同步记录 18只开胸犬基础及急性缺血条件下左心室游离壁心外膜、中层心肌和心内膜心肌细胞的单相动作电位。结果表明交感神经刺激使跨室壁复极离散度 (TDR)减小。急性缺血可使 TDR增加 ,交感神经刺激使 TDR进一步由 (5 4± 7) ms增加到 (83± 13) m s (P<0 .0 1) ,而且可以在中层心肌诱发出早期后除极 (EAD)。β受体阻滞剂可完全阻断交感神经刺激的作用     

冠心病患者Holter监测中ST段动态变化的分析

本文对117例冠心病并有发作性心肌缺血者的24小时 Holter 监测结果进行分析,共检出缺血发作1123阵;24小时内清晨5～8时发作最多,占21.7％;心率增快时发作缺血者67例(57.3％);有典型心绞痛者11例(9.4％),全程无症状者60例(51.3％);缺血时有无疼痛与 ST 段下降程度及有无心梗病史无关。     

Bipolar Esophageal Electrocardiography by Using Standard Limb Leads

Asearlyasin1906,CremerLl]firstre-portedanesophagealelectrocardiogram(ECG)recording.Sincethen,manystud-ies[2'3]0nthissubjecthavebeenundertakenandesophagcealECGshavebeensh0wntobesuperiortosurfaceECGsinidentificationofatrialactivityduringarrhythmia.InesophagealECGs,bipolarECGissuperiortounipolaroneandthefiltered0neissupe-riortothen0n-filteredone.AsthefilteredandbipolarECGrecordingsrequirespecialequipment,itwasimpracticalt0beusedatthebedside.Forbedsidediagnosisofar-rhythmia,HammilandPritc…