细菌性阴道病及实验室诊断的最新研究进展

细菌性阴道病是育龄妇女最常见的生殖道感染性疾病，原因是阴道的微生物平衡失调，并且与多种妇产科并发症密切相关。传统的检测方法包括测量阴道分泌物的pH值及涂片染色寻找线索细胞等。近年来一些快捷、准确的新方法，如胺实验、唾液酸酶实验、积分法及分子生物学方法逐渐被应用于临床诊断。本文对这这几种新的实验室诊断技术作一综述。     

风寒湿痹的给药护理

风寒湿痹是由于外感风寒湿热之邪痹阻于经络骨节、血气运行失畅所引起的肢体酸痛、着重和麻木，它是临床常见的病症。中医治疗风寒湿痹的主要方法是内服汤剂。因为汤剂具有吸收快、疗效快和灵活加减使用的特点。为保证给药质量，提高药物疗效，给药护理则成为重要环节。笔者对30例痹症给药护理的临床情况报告如下。     

慢性胰腺炎致胃潴留1例

患者男,40岁.因恶心、呕吐7日于1997年12月6日入院,发病后无头昏、头痛,无腹痛、腹泻,伴上腹饱胀不适、纳差,呕吐1次/日～2次/日,呕吐物多为隔日食物,无咖啡色样物.不伴寒战、高热,无黄疸.既往有反复腹痛史十余年.     

注射器消毒法的改进

注射器消毒法的改进ＩｍｐｒｏｖｅｍｅｎｔｏｆＤｉｓｉｎｆｅｃｔｉｏｎＭｅｔｈｏｄｓｆｏｒＳｙｒｉｎｇｅ田红岩王建红辛燕①ＴｉａｎＨｏｎｇｙａｎ，ＷａｎｇＪｉａｎｈｏｎｇ，ＸｉｎＹａｎ（ＴｈｅＳｅｃｏｎｄＷｏｒｋｅｒ’ｓＨｏｓｐｉｔａｌｏｆＸｉｓｈａｎ...     

用人工神经网络研究情志活动异常时下丘脑-垂体-卵巢轴紊乱机理

下丘脑是情志活动重要的调控脑区。情志活动异常时下丘脑神经内分泌免疫物质发生变化,它们参与HPO轴功能的复杂调控。文章提出用人工神经网络分析下丘脑对HPO轴的调控,以探讨情志异常时HPO轴紊乱机理。     

42例青年卒中患者与中年组DSA对比分析

目的 应用数字减影血管造影(DSA)了解青年缺血性脑卒中脑血管病变的特点.方法 选择行DSA检查的青年(年龄15～45岁)缺血性卒中患者42例为观察组,同期行DSA检查的中年(年龄46～64岁)缺血性卒中患者60例为对照组,分析青年患者血管病变的发病特点.结果 42例15～45岁患者中有64.3%出现脑血管异常,2例为椎动脉发育较差,4例moyamoya病,3例颅内动脉炎改变,18例血管狭窄和(或)闭塞.60例46～64岁患者中有60.0%出现脑血管异常,2例为椎动脉发育较差,1例moyamoya病,33例血管狭窄和(或)闭塞.15～45岁组患者危险因素中高血压占28.6%(12/42),糖尿病4.8%(2/42),脂代谢异常16.7%(7/42).而在46～64岁组患者中高血压占58.3%(35/60),糖尿病28.3%(17/60),脂代谢异常 30.0%(18/60).46～64岁组患者中合并高血压和(或)糖尿病较15～45岁组患者更常见,两组差别有统计学意义(P<0.01),脂代谢异常均为两组患者的危险因素,差别无显著差异(P>0.05).结论 高血压、糖尿病在46～64岁组患者中更常见,脂代谢异常均为两组患者的危险因素.15～45岁组患者和46～64岁组脑梗死发病率、DSA异常发生率、血管狭窄和(或)闭塞发生率、mRS评分均无显著差异(P>0.05),行血管造影检查能有效发现青年人缺血性卒中的病因.

Abstract：

Objective To investigate the cerebrovascular features in young adults with ischemic cerebrovascular disease. Methods 102 cases (aged from 15 to 64) with ischemic stroke,admitted by head CT/MRI and DSA,were divided into two groups:aged from 15 to 45 group and aged from 46 to 64 group. These data were reviewed retrospectively to determine the classified type and distribution of the cerebrovascular lesions. Results 27 cases in aged from 15 to 45 group (64.3 % ) were found cerebrovascular lesions. Among them, vertebral artery of 2 cases developed poorly,4 cases had moyamoy disease ,3 cases had arteritis, 18 cases had vascular stenosis and/or occlusion. 36 cases in aged from 46 to 64 group (60.0%) were found cerebrovascular lesions, vertebral artery of 2 cases developed poorly, 1 cases was moyamoy disease ,33 cases had vascular stenosis and/or occlusion. Risk factors of cerebral infarction in aged from 15 to 45 group were hypertension ( 28.6%, 12/42), diabetes (4.8% ,2/42), and abnormal lipid metabolism (16.7% ,7/42). Hypertension and diabetes were more frequently in 46 to 64 group(P < 0.01 ), and there was no defference in the abnormal lipid metabolsm between the 2 groups(P > 0.05 ). Conclusion Hypertension and diabetes were more frequently in 46 to 64 group. There was no defference in the incidence of cerebral infarction and cerebrovascular lesions between the 2 groups(P > 0.05 ). DSA can provide the diagnosis and aid in treatment.     

碱性成纤维细胞生长因子对人牙周膜细胞合成层黏连蛋白的影响

牙周膜成纤维细胞（PDLF）是一种具有多种生物学功能和分化潜能的细胞群,在牙周组织重建过程中起重要作用,其增殖和优先迁移是牙周再生获得成功的首要条件,目前的研究表明,碱性成纤维细胞生长因子（bFGF）能促进体外培养的人牙周膜细胞增殖和分化,还能促使PDLF在牙根面上特别是病变牙根的表面附着和增殖。本研究目的是观察在外源性bFGF对体外的PDLF细胞合成层黏连蛋白（LN）的影响。     

老年人带状疱疹误诊1例

病人,男,84岁。反复右季肋区持续性针刺样剧痛1月余。1个月前无明显诱因出现右侧胸痛,疼痛呈持续性针刺样,无头晕、头痛、无黑蒙现象,咳嗽时无胸痛加重。既往有原发性高血压、冠心病、胆囊炎、肋间神经痛、带状疱疹等病史。门诊检查：血、尿、粪常规化验及生化检查正常。胸片及心电图提示：未见异常。诊断为肋间神经痛,