2型糖尿病大鼠胰腺微区血液灌流量与空腹血糖的相关性研究

Objective To observe the dynamic change of microcirculatory hemoperfusion in pancreatic head,body and tail of type 2 diabetic rats and its relationship with fasting blood glucose.Method All Wistar rats were randomly divided into control group(n=130)and experimental group(n=150).The rat model of type 2 diabetes mellitus was established by high-fat,high-sugar feeding combined with low-dose streptozotocin(30 mg/kg).At the 0,4,8,12,16 weeks after the occurrence of diabetes,twenty rats were picked up randomly and respectively from two groups,and microcirculatory hemoperfusion in pancreatic head,body and tail and fasting blood slucose were measured in vivo.Results At the 0,4,8,12,16 weeks after the occurrence of diabetes,fasting blood glucose in experimental group were(10.25±7.98),(14.72±7.51),(19.23±6.09),(22.44±7.45),(26.03±4.96)mmol/L respectively,while microcirculatory hemoperfusion in pancreatic body and tail were(2.46±0.90),(2.79±1.34),(3.15 ±1.24),(3.76±0.99),(4.28±0.23)V respectively.They both increased progressively(P<0.05).No significant changes were found in pancreatic head compared with control group(P>0.05). Microcirculatory hemoperfusion in pancreatic body and tail was positively associated with fasting blood glucose(r=0.3786,P<0.05).Conclusion Microcirculatory hemoperfusion in pancreatic body and tail increased with the increase of fasting blood glu cose in type 2 diabetic rats.     

带锁髓内钉治疗长骨骨折47例护理体会

带锁髓内钉治疗骨干骨折是骨科内固定技术一大进展,它具有固定牢靠、创伤小、降低感染率、骨折愈合率高,允许早期功能锻炼等优点[1],带锁髓内钉以其优良的生物力学性能被广泛应用于四肢骨折的治疗,我院2005年11月至2009年11月利用带锁髓内钉治疗股骨和胫骨骨折共47例,术后采取了有效护理措施,效果良好,现将护理体会报告如下.     

延续性护理干预在肾衰竭血液透析患者中的应用

目的探讨延续性护理干预在肾衰竭血液透析患者中的应用效果。方法选取肾衰竭血液透析患者300例按随机数字表法分成观察组和对照组,各150例。对照组实行常规护理,观察组在常规护理的基础上给予延续性护理干预。对比2组患者护理前、后的自护理能力、营养状况及并发症发生率。结果 2组护理前自护理能力相关指标(自我概念、自护责任感、自护技能、健康知识、总得分)及营养状况各指标比较差异无统计学意义(P0.05);观察组护理后自我概念、自护责任感、自护技能、健康知识及自护能力总得分均高于对照组(P0.05);观察组护理后Alb、PA、Hb、TRF高于对照组(P0.05);观察组并发症总发生率低于对照组(P0.05)。结论延续性护理干预能有效地提高肾衰竭血液透析患者的自护能力,并改善营养状况和降低并发症发生率。