论著性文稿中摘要的书写

论著性文稿须附中、英文摘要 ,内容包括目的、方法、结果 (应给出主要数据 )、结论四部分 ,各部分冠似相应的标题 ,采用第三人称撰写 ,不用“本文”、“作者”等主语。考虑到我国读者可参考中文原著资料 ,为节省篇幅 ,中文摘要可简略些 ( 2 0 0字左右 ) ,英文摘要则要相对具体些 ( 4 0 0个实词左右 )。英文摘要尚应包括文题、作者姓名 (汉语拼音 )、单位名称、单位所在城市名及邮政编码、国别。作者应列出前 3位 ,3位以上加“ｅｔａｌ” ;作者不属同一单位时 ,在第一作者姓名右上角加“ ” ,同时在单位名称首字母左上角加“ ”。例如 :Ｚ…     

Survival of cervical cancer patients in Germany in the early 21st century: A period analysis by age, histology, and stage

Abstract Purpose. Population-based studies on cervical cancer providing survival estimates by age, histology, and stage have been sparse. We aimed to derive most up-to-date and detailed survival estimates for cervical cancer patients in Germany. Methods. We used a pooled German national dataset including data from 11 cancer registries covering a population of 33 million people. Included were 15 685 patients diagnosed with cervical cancer from 1997 to 2006. Period analysis was performed to calculate the five-year relative survival (RS) 2002-2006. Trends in survival between 2002 and 2006 were examined using model-based period analysis. Age-adjustment was done using five age groups (15-44, 45-54, 55-64, 65-74, and 75 + years). Results. Overall, age-adjusted five-year relative survival in 2002-2006 was 64.7%. A strong age gradient was observed, with five-year RS decreasing from 81.7% in age group 15-49 years to 46.3% in age group 70 + years. Prognosis furthermore strongly varied by stage, with age-adjusted five-year RS reaching 84.6% for localized, 48.2% for regional, and 17.9% for distant stage. From 2002 to 2006, a significant improvement (4.7 percent units) in overall age-adjusted five-year RS was seen. The improvement was most pronounced for age groups 55-64 years (from 54.2 to 65.6%) and 65-74 years (from 50.0 to 58.1%). Conclusion. In this first comprehensive population-based study from Germany, prognosis of cervical cancer strongly varied by age and stage. Prognosis continued to improve, in particular in age range 55-74 years, in the five-year period assessed.     

原发性子宫淋巴瘤的MRI诊断（5例报告及文献复习）

目的探讨子宫淋巴瘤的MRI特点,以提高对其认识及诊断能力。方法回顾性分析5例经临床及病理证实的原发性子宫淋巴瘤的MRI表现并作文献复习。3例患者行MR平扫及增强检查,2例行平扫,行横断面SE T1WI、FSE T2WI以及矢状面、冠状面FSE T2WI。增强病例均行DWI扫描。结果5例患者病理结果均为弥漫性大B细胞淋巴瘤,其中肿瘤位于宫颈2例,宫体2例,1例宫体宫颈均受累,最大者16cm×12cm,最小者直径3cm。MRI表现T1WI均呈等低信号（以肌肉信号为参照）,信号均匀,无明显出血信号改变,T2WI呈稍高信号,其中4例肿瘤内均可见多个形态不规则结节灶,且之间可见条索状低信号带分隔,未见明显囊变及坏死信号,1例呈均匀高信号,无结节灶及条索状分隔。增强扫描1例呈轻度均匀强化,边界清晰,2例可见肿瘤内结节灶轻度强化,而结节间条状分隔线强化程度略高于结节灶。4例T2WI肿瘤内可见子宫内膜线或宫颈黏膜线完整存在于肿瘤内。3例DWI呈显著高信号。结论子宫淋巴瘤MRI表现有一定特征性,MRI对该病的诊断具有很高的价值。     

脐血中CD56brightCD16dim/-NK细胞亚群的检测

目的了解新生儿脐血NK细胞和CD56brightCD16dim/-NK细胞亚群的比率,探讨CD56bright CD16dim/-NK细胞在脐血低免疫应答中的作用.方法使用血细胞分析仪计数淋巴细胞;采用流式细胞术检测脐血、母亲及对照组中NK细胞和CD56brightCD16dim/-NK细胞亚群的比率.结果脐血中淋巴细胞计数显著高于母亲及对照组;NK细胞比率无显著性差异;CD56brightCD16dim/-NK细胞高于母亲及对照组;母亲组CD56brightCD16dim/-NK细胞高于对照组.结论脐血中丰富的CD56brightCD16dim/-NK细胞是脐血低免疫应答的原因之一.     

MALDI质谱成像的样本制备技术及应用研究进展

MALDI质谱成像技术(Maldi tof ImagingMass Spectrometry,MALDI-IMS),是利用MALDI质谱技术将得到的蛋白组学数据,结合计算机辅助成像产生分子图像,进而描绘出组织上已知及未知分子分布情况的新技术。该技术已被广泛应用于生命科学的很多领域,如动植物生理学、病理学[1-3]、药物研发[4-6]等。1样品制备技术MALDI质谱成像实验的关键是样品的制备[7],它主要包括冰冻切片的制备和基质的选择及应用等。