尿液干化学法与常规湿化学法的比较

干化学法在尿液检验中各医院普遍采用方法，简单、快速过筛试验比较方便。但受许多因素(pH值、维生素C及一些药物)影响易出现假阳性，而且也不能全取代镜检。我们与常规湿化学法做了比较，尿胆原、胆红素、尿蛋白检出率都高于湿化学法，尿糖低于斑氏法，这与其针对葡萄特异性强有关。血红蛋白、白细胞、丙酮湿化学法差别不大，但与镜检有明显差别，干化学法不能代替镜检，同时做镜检很有必要。     

胶囊式测压系统在消化道传输功能测定中的初步应用

消化道内压力和传输时间是反映消化道动力功能的重要参数,也是了解慢传输性便秘患者病情程度的重要指标,但一直缺乏反映生理状态的检测方法.     

电视胸腔镜食管癌切除术技巧探讨

2002年10月～2003年12月,我们应用电视胸腔镜(VATS)行食管癌切除术16例,均取得良好效果,现就有关手术技巧探讨如下.     

老年人冠脉搭桥术术后功能状况的改善[英]

目前，美国人均寿命76．4岁，有620万人患有一种或多种心血管疾病。每年施行60万例冠脉搭桥术，并且估计年递增7％-8％。临床工作最关心的是病人最大限度的功能状况改善。通常，对冠脉搭桥术结果成功与否的评价是应用发病率和死亡率。     

影响肿瘤患者的心理社会因素研究

目的 探讨与恶性肿瘤相关的心理社会危险因素.方法 运用心理评定量表对60例已明确诊断的恶性肿瘤患者及55例一般情况与之相匹配的健康对照者分别进行测评,包括生活事件评定量表(LES)、艾森克人格问卷(EPQ)、简易应对方式问卷(SCSQ)、社会支持评定量表(SSRS).结果 恶性肿瘤患者在病前经历的负性生活事件频数及刺激量、神经质得分、消极应对方式得分显著高于健康组(P<0.05);而内外向得分、积极应对方式得分、主观社会支持及支持的利用度得分显著低于健康组(P<0.05).Logistic回归分析显示:影响恶性肿瘤发病的心理社会危险因素为负性生活事件的频数、神经质人格、主观社会支持.结论 心理社会因素是恶性肿瘤发生的重要因素之一,应加强对某些个体的心理社会干预.     

192例原发性肾小球肾炎病理类型及临床特点

１９２例原发性肾小球肾炎病理类型及临床特点８医院（山东泰安２７１０００）谷红霞高鑫张明张玲丁春辉王培杰１４８医院杜玉原发性肾小球肾炎是我国常见的也是最重要的一类肾脏疾患，并存在着各种组织学类型。由于生活环境及体质的不同，各地区肾小球疾病的组织学类型存...     

经皮球囊扩张治疗Budd—Chiari综合征

本文对Ｂｕｄｄ－Ｃｈｉａｒｉ综合征的临床表现、超声检查、下腔静脉及肝静脉造影进行了分析。结合对３２例ＢＣＳ患者的介入治疗体会，提出了ＢＣＳ的类型与介入治疗方法的选择。认为用经皮下腔静脉或／和肝静脉球囊扩张和血管内支架置入是治疗ＢＣＳ的安全、有效的方法。     

老年直肠癌患者105例治疗体会

直肠癌是我国老年人常见的恶性肿瘤之一，老年直肠癌患者早期症状常不明显，就诊时多属晚期，而且老年人常有各种疾病并存，手术风险较大。我科收治的≥60岁的老年直肠癌患者105例，临床治疗体会总结报道如下。     

放射线联合p53基因及内皮抑素治疗小鼠前列腺癌皮下移植瘤

Objective To test the hypothesis that p53 gene therapy combined with endostatin can enhance tumor response to radiation therapy of RM-1 mouse xenograft prostate cancer and to investigate its mechanism. Methods A mouse prostate cancer model was established. Then mice with xenograft tumor were randomly divided into group A (control), B (radiation), C (radiation and rAdp53), D (radiation and rh-endostatin) and E (radiation and rAdp53 and rh-endostatin). On day 1, rAdp53 was injected intra-tumorously with 1 × 1010 vp per animal to group C and E. From day 1 to 14, rh-endostatin was given 15 mg/kg intraperitoneally daily to group D and E. On day 4 single fraction of 15 Gy was given to tumors in groups B, C, D and E. Normal saline was injected intra-tumorously or intraperitoneaUy accordingly as control. No treatment was done to group A. Tumor volume was measured daily. Samples were collected on Days 5, 10 and 15. Ki67, CD31, p53 and VEGF were detected by means of immunohistochemistry. Results (1) Radiation alone, radiation combined with intra-tumorous injection of Adp53 and/or intraperitoneal injection of rh-endostatin resulted in tumor growth arrest of RM-1 cells in vivo (P = 0.000). Radiation combined with both rAdp53 and rh-endostatin was the most effective treatment (P < 0.05). (2) All the four treatment groups had a decreased expression of mutant type P53 (P = 0.000). The expression of Ki67 in groups B and C were equal (P 0.05) and increasing (P = 0.000), respectively. Group D had a up-down-up curve (P < 0.05), but group E had a up-down one. On day 5 the expresion of VEGF in group E was the lowest (P < 0.05). An increased expression of MVD compared with the control was shown, and MVD in groups C, D and E were always higher than that in the control (P < 0.05). Conclusions The limitation of radiotherapy could be overcome by combination with beth p53 gene therapy and endostatin on the growth of mouse prostate cancer cell. Radiation, rAdp53 and endostatin have their own role but they can be interacted with each other.     

血脂诸危险因素与冠心病之间关系的研究

血脂诸危险因素与冠心病之间关系的研究中国医科大学附属第一医院（１１０００１）霍海洋胡健齐国光曾定尹辽宁省人民医院张明血脂代谢异常在冠状动脉粥样硬化性心脏病（冠心病，ＣＨＤ）病因学中的意义多年来一直是人们研究的热点。然而，诸多血脂危险因素中，何者与ＣＨ...