椎间孔注射治疗下腰部急慢性腰腿痛65例疗效分析

本文报道用强的松龙,透明质酸酶椎间孔或其外口注射治疗65例急慢性腰腿痛病人的疗效。介绍了操作方法,椎间孔局部解剖及效果进行了分析,结论认为本法尤其适合于急性腰腿痛病人,优良率达67%.     

两种固体炮制辅料的选材与制备

两种固体炮制辅料的选材与制备唐永明(安徽省安庆市中医院246003)本文仅将容易引起混乱或被忽视的两种固体辅料的选材与制备工艺简述如下。1砂1.1选材无名异:主含二氧化锰和氧化铁(Fe2O3)。生品在炒制过程中有爆裂现象发生,须经蜜炙后方可使用。且不易购得真品,故大部分地区早已废弃不用。石英:即氧化硅石荧类的乳石英。本品乃河砂和海岩砂的主要成分,质地坚硬,炒制过程不易破碎(纯品价钱虽贵,但河砂广泛易得),故为首选材料。1.....     

Study on Distribution of HFRS Virus in the Tissuses and Cells of Human Body

Immunochemical rnethods,viral tissue culture and dlectron microscopic observationtechiniques were used to study the distribution of HFRS virus in the tissues and cells of patients withHFRS and sorne of their abotive faus.The results showed that HFRS virus could infect many hu-man organs and cells and pass through plaoenta and blood-brain barrier,and was characteristic ofpantropical infection,the duration of the viremia of the patients being mostly near a week.Thestudy is valuable for elucidation pathogenesis of the disease.     

中国非小细胞肺癌患者血清DAPK基因、p16基因启动子甲基化的分析

Objective： To evaluate the clinical significance of the aberrant methylation of DAPK gene and p16 gene in sera from 65 NSCLC patients from Nanjing General Hospital of Nanjing Command, China. Methods： A methylation-specific PCR （MSP） was performed for the detection of promoter hypermethylation of DAPK gene and p16 gene in blood DNA from 65 cases of NSCLC, and to analyze the relation of the aberrant methylation of DAPK gene and p16 gene and the clinicopathological data. Results： 30.8% （20/65） of the sera from 65 cases of NSCLC showed hypermethylation for DAPK promoter and 43.1% （28/65） the same for p16 promoter, whereas no methylated DAPK gene promoter and p16 gene promoter were found in sera from the patients with lung benign diseases and normal controls. Methylated DAPK gene promoter and p16 gene promoter in sera were not closely correlated with the pathological classification, stage, metastasis and differentiation in NSCLC. Conclusion： Detection of the aberrant methylation of DAPK gene and p16 gene in blood DNA from NSCLC patients might offer an effective means for the earlier auxiliary diagnosis of the malignancy.     

中药固体炮制辅料探源

中药固体炮制辅料探源唐永明①赵秋蕊②传统上，习惯于把中药炮制工作归纳为“水制”、“火制”、和“水火共制”三类。本文所讨论的中药固体炮制辅料（以下简称“辅料”），乃是专指参与“火制”过程的各种固体物质。作为辅料，除极少数外，一般都在炮制结束时被弃去不用...     

中国非小细胞肺癌患者血清DAPK基因、p16基因启动子甲基化的分析(英文)

目的分析65名中国南京军区南京总医院的非小细胞肺癌(NSCLC)住院患者血清中DAPK、p16启动子区域甲基化的改变状况及其临床意义。方法运用甲基化特异性PCR技术,检测65例NSCLC患者血清DAPK、p16基因启动子区域甲基化的改变情况,并分析与临床病理资料的关系。结果 NSCLC患者血清DAPK基因甲基化检出率为30．8％(20/65),p16基因甲基化检出率为43．1％(28/65),而正常对照组和良性肺部疾病组血清未检出DAPK基因、p16基因甲基化,DAPK基因、p16基因甲基化检出率与NSCLC病理类型、分期及转移状态无明显关系。结论 DAPK基因、p16基因检出启动子区域异常甲基化是NSCLC早期辅助诊断的分子标志物之一。