针刺联合点扳抖手法治疗腰椎间盘突出症缓解期50例随机对照试验

目的 评价针刺联合点扳抖手法治疗腰椎间盘突出症缓解期的临床疗效与安全性。方法 104例腰椎间盘突出症缓解期患者随机分为治疗组和对照组各52例。治疗组采用针刺联合点扳抖手法治疗,针刺选取腰部夹脊穴（双侧）、阿是穴、肾俞穴（双侧）、环跳穴（双侧）、委中穴（患肢对侧）、承山穴（患肢对侧）;对照组采用腰椎牵引联合穴位超声脉冲透入治疗（穴位同治疗组针刺穴位）,每次20 min,两组均每周3次,共3周。主要结局指标为腰椎间盘突出症症状与体征的评分改善率,分别于治疗1周、治疗3周、1个月随访时、3个月随访时计算;次要结局指标为日本整形外科学会（JOA）评分、视觉模拟评分法（VAS）评分和Oswestry功能障碍指数问卷表（ODI）评分（包括ODI总积分、坐位评分和站立评分）,分别于治疗前、治疗1周、治疗3周、1个月随访时、3个月随访时各评价1次;3个月随访时评定临床疗效;记录患者不良事件发生情况,以及治疗前后血常规、尿常规、大便常规及心电图情况,评价安全性。结果 两组患者各脱落2例,最终纳入分析各50例。治疗1周、治疗3周、1个月随访时及3个月随访时,治疗组腰椎间盘突出症症状与体征的评分改善率均高于...     

骨折愈合应力适应性的研究

本研究通过传感器电测技术、光导纤维在体植入观察与X线灰度分析方法研究了骨折愈合的应力适应性，探讨了骨折端受力、肌肉动力、骨痂密度、血管再生与骨折愈合的关系。对骨折愈合过程活体断端力学环境、活体组织学变化过程及愈合组织的物质梯度连续变化进行了开创性的实验和理论研究。     

中药改善地方性氟骨症患者症状和能力的临床观察

目的观察中药改善地方性氟骨症患者症状和能力的疗效。方法对根据地方性氟中毒诊断标准确诊的30例氟骨症患者,给予以马钱子为主要成分的中药12服治疗,疗程为3个月。观察治疗前后患者自身症状和能力的改善情况。结果30例中显效21例,有效9例,总有效率100％。结论以马钱子为主的中药治疗地方性氟骨症疗效确切。     

全内脏反位腰椎椎管狭窄症1例报告

<正>全内脏反位(situs inversus totalis,SIT)是一种少见的先天发育结构异常,胸腹腔脏器及血管分布呈镜像反位状态,据报道内脏反位的发生率约1/10 000左右^[1]。国内外文献多报道全内脏反位行胸腹部外科及血管介入手术,鲜有全内脏反位脊柱疾患病例报道^[2～4]。本科成功对1例全内脏反位腰椎椎管狭窄症患者行腰椎融合术,现报道如下。     

骨折愈合应力适应性的研究

本研究通过传感器电测技术、光导纤维在体植入观察与X线灰度分析方法研究了骨折愈合的应力适应性,探讨了骨折端受力、肌肉动力、骨痂密度、血管再生与骨折愈合的关系。对骨折愈合过程活体断端力学环境、活体组织学变化过程及愈合组织的物质梯度连续变化进行了开创性的实验和理论研究。     

椎间隙灌洗法治疗腰椎后路内固定术后切口早期深部感染的疗效分析

目的:探讨腰椎内固定术后切口早期深部感染的原因、诊断要点及治疗手段。方法:自2001年1月至2011年12月,对10例采用椎间隙灌注冲洗法治疗的腰椎后路内固定术后切口早期深部感染患者的临床资料进行回顾性分析。其中男1例,女9例;平均年龄63岁,感染发病时间平均为术后第6天。主要临床表现包括不同程度腰腿痛加重、体温升高、伤口新鲜渗液及血炎性指标增高等,疗效评估则以伤口是否Ⅰ期愈合为主要标准。结果:10例患者均获得随访,随访时间平均为1年5个月。9例伤口Ⅰ期愈合,无复发,也无术后并发症出现,1例患者后续进行多次清创术,疗程共7个月,最后将椎弓根螺钉取出后伤口愈合,随访1.5年未复发。结论:腰椎内固定术后深部感染尽早行手术清创及椎间隙灌注冲洗法治疗,可获得满意疗效并能最终保留内固定,避免过多切除软组织及椎间隙深层置管是手术成功的关键。     

中药疗法改善中度氟骨症患者肢体关节功能的随机对照研究

Objective To observe the improving effect in joint function of moderate skeletal fluorosis treated by traditional Chinese medication(main ingredient was Strychnine).Methods From December 2007 to July 2009,120 moderate skeletal fluorosis patients met the inclusion criteria were divided into the treatment group(60 cases)and the control group(60 cases)in the skeletal fluorosis hospital of Xinzhou,the treatment group was given basic treatment and traditional Chinese medication,the control group wa8 given basic treatment and placebo.The treatment lasted 12 weeks,follow up 24 weeks.Before treatment,after treatment 4 weeks,8 weeks,12 weeks,36 weeks,a third party evaluate comprehensive function of both upper and lower limb and joint dysfunction.Results The main effect of both drugs was statistically significance in the scores of the upper forearm in the finger by touching the posterior contralateral ear, upper arm touched by the finger back in the opposite corner subscapularis function, lower limb function and single-joint dysfunction(F values were 4.08,14.32,35.81,13.02, all P<0.05), the main effect of time also was significant (F values were 82.63,72.82,277.33,328.16, all P<0.05),①the upper forearm in the finger by touching the posterior contralateral ear functions:At the time of 8,12 weeks,scores of the treatment group were lower than those of before treatment and control group (all P<0.05);At the time of 36 weeks,scores of the treatment group were lower than that 12 weeks(all P<0.05);At the time of 8,12,36 weeks, scores of the control group were lower than those of before treatment(all P < 0.05);②upper arm function, namely fingers touching the opposite corner subscapularis:At the time of 4,8,12 weeks, scores of the treatment group were lower than those of before treatment(all P<0.05); At the time of 36 weeks, scores of the treatment group were lower than that 12 weeks(all P<0.05); At the time of 8,12,36 weeks, scores of the treatment group were lower than those of the control group (all P<0.05);③Lower extremity functions: At the time of 8,12 weeks,scores of the treatment group were lower than those of before treatment and control group (all P<0.05);At the time of 36 weeks, scores of the treatment group were lower than that 12 weeks(all P<0.05) ; At the time of 8,12,36 weeks, scores of the control group were lower than those of before treatment (all P<0.05);④single joint functions:At the time of 4,8,12 weeks,scores of the treatment group were lower than those of before treatment(all P<0.05); At the time of 36 weeks,scores of the treatment group were lower than that 12 weeks(all P<0.05) ; At the time of 8,12,36 weeks, scores of the control group were lower than those of before treatment(all P<0.05);At the time of 4,8,12,36 weeks, scores of the treatment group were lower than those of control group(all P<0.05);⑤At the end of treatment and follow-up,the improvement rate in joint functions in the treatment group were 88.33% (53/60),93.33% (56/60); the control group were 28.07%(16/57),40.35%(23/57), (Fisher test, P<0.01,X2=56.21, P<0.01). Conclusion Traditional Chinese medication(its main ingredient is Strychnine), an effective drug for improving joint dysfunction in patients suffering from moderate skeletal fluorosis, is simple and effective.     

经皮椎间孔镜技术结合选择性神经根阻滞在单节段退行性腰椎管狭窄症的临床应用

目的探讨经皮椎间孔镜技术(percutaneous transforaminal endoscopic discectomy,PTED)结合选择性神经根阻滞(selective nerve root block,SNRB)治疗单节段退行性腰椎管狭窄症(lumbar spinal stenosis,LSS)的临床效果。方法纳入2015年3月~2017年3月于手术治疗的84例单节段LSS患者,采用PTED髓核摘除治疗的38例设为对照组,在此基础上加用SNRB治疗的46例设为观察组。对两组患者进行综合疗效评价,记录术后并发症发生情况。结果两组治疗后各随访时间VAS评分、ODI指数均显著低于治疗前,且治疗1 d、1个月时观察组显著低于对照组(P0.05),治疗6个月、末次随访时的差异无统计学意义(P0.05);观察组末次随访手术疗效优良率为95.65%,对照组为94.74%,组间差异无统计学意义(P0.05);观察组术后切口感染、麻木发生率显著低于对照组(P0.05),慢性疼痛、神经损伤发生率差异无统计学意义(P0.05)。结论与单纯的PTED手术相比,SNRB结合PTED手术治疗LSS能显著降低术后早期疼痛症状,腰椎功能恢复更快,能显著降低切口感染、麻木等并发症发生率。     

郭氏马钱汤对中度氟骨症肘、膝关节屈伸运动的影响

目的 观察治疗前后中度氟骨症患者的肘、膝关节屈伸活动度数,评价郭氏马钱汤对中度氟骨症患者肘、膝关节届伸功能的改善作用.方法 将54例中度氟骨症患者随机分为两组,治疗组采用郭氏马钱汤治疗,8周后改服骨康宁胶囊;对照组采用空白安慰剂,8周后改服骨康宁胶囊安慰剂.结果 治疗结束时两组肘关节的屈伸功能改善明显,治疗组优于对照组(P<0.05),而膝关节的屈伸功能改善差异无统计学意义;24周随访时肘、膝关节的屈伸功能均明显改善,治疗组较对照组差异有统计学意义(P<0.05).结论 郭氏马钱汤可改善中度氟骨症患者的肘、膝关节属伸功能.     

郭氏马钱汤对中度氟骨症肘、膝关节屈伸运动的影响

目的 观察治疗前后中度氟骨症患者的肘、膝关节屈伸活动度数,评价郭氏马钱汤对中度氟骨症患者肘、膝关节届伸功能的改善作用.方法 将54例中度氟骨症患者随机分为两组,治疗组采用郭氏马钱汤治疗,8周后改服骨康宁胶囊;对照组采用空白安慰剂,8周后改服骨康宁胶囊安慰剂.结果 治疗结束时两组肘关节的屈伸功能改善明显,治疗组优于对照组(P<0.05),而膝关节的屈伸功能改善差异无统计学意义;24周随访时肘、膝关节的屈伸功能均明显改善,治疗组较对照组差异有统计学意义(P<0.05).结论 郭氏马钱汤可改善中度氟骨症患者的肘、膝关节属伸功能.