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61.
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63.
In critical limb ischemia (CLI), an underlying principle of treatment is that it takes more oxygenated blood to heal a wound than to maintain tissue integrity. Urgent restoration of perfusion to the ischemic territory, not long-term patency of the target vessel, is the primary treatment goal. However, in patients with CLI treated by surgical bypass, loss of graft patency is associated with poor outcomes. We decided to address the conventional wisdom that restenosis is not a major concern in CLI as long as tissue healing occurs in patients undergoing endovascular revascularization. We retrospectively reviewed the records of consecutive patients treated for CLI with infra-popliteal percutaneous revascularization from 2007 to 2009. Those with prior ipsilateral percutaneous revascularization for CLI formed the study population. Among 29 CLI patients treated for infra-popliteal revascularization, six patients had a history of prior successful ipsilateral revascularization for CLI. All six patients were free of rest pain and ulcers at the 60-day follow-up. The median time interval between the two percutaneous revascularization procedures was 21 months (quartile ranges: 25th = 4.5 months, 75th = 36 months). Five of the six patients had restenosis of a previous lesion, while the sixth patient had a de novo lesion causing recurrent CLI. In conclusion, we found that one in five patients receiving infra-popliteal angioplasty for CLI has had a similar percutaneous revascularization procedure in the past. Among these patients most cases were for restenosis rather than de novo lesions. Further research is needed to determine whether the incidence of recurrent CLI is due to de novo lesions or restenosis. Close clinical follow-up of these patients and maintaining long-term patency with endovascular techniques will likely reduce CLI recurrence. 相似文献
64.
Sibel Zehra Aydin Pamir Atagunduz Burak Erer Cengiz Bahadir Nevsun Inanc Haner Direskeneli 《Rheumatology international》2010,30(3):415-417
In the current study we aimed to investigate the effect of MBL deficiency in radiographic damage of the spine in a large group
of AS patients. One hundred and ninety-one AS patients and 85 healthy controls were studied. Disease activity, radiological
scores, and demographic features were recorded. MBL levels were measured with standard ELISA kits. Results showed that median
MBL levels in AS and healthy controls were 2,530 (range 0–5,861) ng/ml and 3,415 (0–7,950) ng/ml, respectively (p = 0.1). MBL deficiency (<500 ng/ml) was comparable in both groups (%21.5 in AS, % 17.6; p = 0.5). Disease activity, clinical picture, and therapies were not associated with MBL levels. Both BASRI and mSASSS scores
were found similar in AS patients with or without MBL deficiency [BASRI: MBL < 500 ng/ml: 6(2–12), MBL ≥ 500 ng/ml: 6(2–12);
p = 0.75], [mSASSS: MBL < 500 ng/ml: 3(0–72), MBL ≥ 500 ng/ml: 5(0–72); p = 0.81]. We conclude that MBL deficiency prevalence is not increased in AS patients and it is not a cause of a severe radiographic
damage. 相似文献
65.
Cetuximab is an epidermal growth factor receptor inhibitor used in metastatic colorectal cancer, and head and neck cancers. Several cutaneous side effects due to cetuximab such as acne-like rash, pruritus, dry skin, desquamation, hypertrichosis, and paronychia have been reported so far. A 59-year-old male patient with metastatic colon cancer referred to our outpatient clinic for his lesions on the dorsal surfaces of his hands and wrists, and on thighs developing after the chemotherapy. He was diagnosed as neutrophilic eccrine hydradenitis related to cetuximab in the light of clinical and histopathological findings. According to our knowledge, this is the first reported case of neutrophilic ecrine hydradenitis due to cetuximab. 相似文献
66.
Deniz Evcik Saime Ay Aral Ege Aycan Turel Vural Kavuncu 《Clinical orthopaedics and related research》2009,467(8):2077-2082
The Knee Outcome Survey-Activities of Daily Living Scale (KOS-ADLS), originally developed in English, is a valid and reliable
self-reported instrument used for patients with various painful knee conditions. We adapted the KOS-ADLS to Turkish and tested
its reliability and validity. We enrolled 142 patients with knee pain in the study. The patients were randomized into two
groups: Group 1 (n = 75) completed the questionnaire twice a week for assessing test-retest reliability and Group 2 (n = 67)
answered the questionnaire and performed additional tests for assessing validity. The intraclass correlation coefficient ranged
from 0.98 to 0.99 with high internal consistency (Cronbach’s alpha, 0.89). Validity-related tests included pain measurement
with a visual analog scale and functional tests, including time measurements for the get-up-and-go and ascending/descending
stairs tests. The visual analog scale score correlated with total score (r = 0.56), function total score (r = 0.53), and symptom
total score (r = 0.45). The ascending/descending stairs test correlated with total score (r = 0.47), function total score
(r = 0.49), and symptom total score (r = 0.31). The get-up-and-go test weakly correlated with all three scores. The Turkish
version of the KOS-ADLS is reliable and valid in evaluating the functional limitations of patients with knee pain.
Each author certifies that he or she has no commercial associations (eg, consultancies, stock ownership, equity interest,
patent/licensing arrangements, etc) that might pose a conflict of interest in connection with the submitted article.
Each author certifies that his or her institution has approved the human protocol for this investigation, that all investigations
were conducted in conformity with ethical principles of research, and that informed consent for participation in the study
was obtained.
This study was performed at Ufuk University and Kocatepe University. 相似文献
67.
Fatma Zehra Oztek Osman Ipsiroglu Thomas Mueller Christoph Aufricht 《Pediatric nephrology (Berlin, Germany)》2009,24(10):2081-2085
Abstracts
The XXXIV Spanish Congress of Pediatric Nephrology 4-7 June 2008, Sevilla, Spain 相似文献68.
The aim of this study is to investigate the homocysteine, folic acid, and vitamin B(12) levels in epileptic children receiving antiepileptic drugs. A total of 25 children with idiopathic epilepsy (8 valproate, 11 carbamazepine, and 6 oxcarbazepine) and 10 healthy children were included in the study. The mean homocysteine, folic acid, and vitamin B(12) levels in the study group were 7.57 +/- 3.78 micromol/L (normal = 5-15 micromol/L), 10.19 +/- 4.05 ng/mL (normal = 3.0-17 ng/mL), and 428.20 +/- 256.12 pg/mL (normal = 193-983 pg/mL), respectively. The differences between the mean plasma homocysteine, folic acid, and vitamin B(12) levels of the study and control groups were not significant (P = .522; P = .855; P = .798, respectively). However, plasma homocysteine levels were higher than the normal cutoff point accepted for childhood in 4 (16%) of the study patients. Out of these 4 children, 3 were from the carbamazepine group and 1 was from the valproate group. Although the number of the study patients is limited, the authors recommend assessment of plasma homocysteine, serum vitamin B(12), and folic acid levels in children receiving enzyme-inducing antiepileptic drugs. 相似文献
69.
70.
Ergun K Golbasi Z Cagli K Altinsoy A Mustafa Ulas M Temucin T Arat N Topaloglu S Deveci B Ertan A 《Echocardiography (Mount Kisco, N.Y.)》2007,24(4):425-429
Cardiac papillary fibroelastoma (CPF) is a rare cardiac neoplasm predominantly affecting the cardiac valves. Although it is most commonly an incidental finding, it can result in life-threatening complications, such as coronary and cerebral embolism, acute valvular dysfunction, and sudden death. In this report, we describe a case of a patient with aortic valve papillary fibroelastoma, which presented with sudden vision loss due to branch retinal artery occlusion. To the best of our knowledge, this is the third case of CPF-related retinal artery embolism in English literature. 相似文献