双眼视差视觉诱发电位与立体视觉的关系初探

作者采用双眼视差视觉诱发电位（VEP）记录了18名正常人和9名斜视患者（立体盲），结果正常人视觉刺激VEP P₁₀₀振幅明显高于非视差刺激者；斜视患者视差刺激与非视差刺激VEP P₁₀₀振幅差异无显著性；正常人视差刺激VEP P₁₀₀振幅增加的幅度值[（DSA-NDA）/NDA]明显高于斜视患者。 （中华眼底病杂志，1992，8：10-13）     

病毒性肝炎病人血浆VitE水平及其临床意义

观测了急性肝炎和重症肝炎病人血浆ＶｉｔＥ及Ｌｐｏ水平及其动态变化。急性肝炎和重症肝炎病人血浆ＶｉｔＥ低于对照组，Ｌｐｏ高于对照组，均以重症肝炎更明显，且死亡病例血浆ＶｉｔＥ低于存活者。部份病人口服ＶｉｔＥ不能提高其血浆水平，并随病情加重而逐渐降低。讨论了病毒性肝炎病人血浆ＶｉｔＥ降低与Ｌｐｏ升高的关系及其临床意义，认为动态观测血浆ＶｉｔＥ可作为判断重症肝炎病情进展及预后的参考。     

实验性单纯疱疹病毒Ⅰ型感染兔眼部扫描电镜观察研究

应用ＤＭＳＯ（Ｄｉｍｅｔｈｙｌｓｕｌｆｏｘｉｄｅ二甲基亚砜）冷冻割断制样扫描电镜技术首次动态观察了不同感染阶段（ｐｏｓｔＩｎｆｅｃｔｉｏｎ，ＰＩ）实验性单纯疱疹病毒性角膜炎（ＨＳＫ）兔的角膜、三叉神经节（ＴＧ）泪腺等组织的病变情况。初步报告并分析了各组织病变的扫描图像结果，并对冷冻割断法观察扫描电镜的原理及优缺点予以讨论，认为该技术应用于眼部单疱病毒感染的研究图像清晰、直观、简便可行，是一种有实用价值的方法。     

阳城县居民吸烟状况调查分析

对阳城县3646名15岁以上人群吸烟状况分析表明,男性吸烟率63.71％,女性吸烟率0.64％,男女合计吸烟率31.49％,并对不同年龄、职业、文化程度与吸烟率的关系进行了分析。吸烟心理动机:“烟草成瘾”占32.06％,“消遣”占28.48％,“解除疲劳”占16.90％,“交际”占22.56％。吸烟人群的4周患病率和慢性病患病率均高于不吸烟人群,两组差别有显著性(P<0.05,P<0.001)。     

城市污灌废水的致突变性检测及色谱/质谱分析

应用Ames致突变试验,对比研究了武汉市易家墩、黄孝河污灌区污灌废水与土壤的致突变性。同时应用色谱/质谱(GC/MS)分析技术。测定了主要污水中有机污染物的化学组成。结果表明:罗家渠废水的致突变活性最强;受各条污水灌溉的土壤的致突变活性顺序与相应废水的强弱顺序一致;罗家渠废水中致突变致癌物主要是萘、联苯等。     

F344／N－Smu－D大鼠生长发育若干生物学特性的检测

Ｆｉｓｃｈｅｒ３４４大鼠在国外广泛应用于肿瘤研究与慢性毒性试验，八十年代中期引入我国。我们对Ｆ３４４／Ｎ－Ｓｍｕ－Ｄ大鼠的生长发育的若干生物学特性进行了检测。结果表明，该品系大鼠体型较ＳＤ大鼠与Ｗｉｓｔａｒ大鼠小，除睾丸、垂体、肾上腺、乳腺外的大部分器官与组织的自发性肿瘤的发生率相对较低，将Ｆ３４４／Ｎ－Ｓｍｕ－Ｄ大鼠种群与Ｆ３４４／ＤｕＣｒｊ种群比较，在体重、耗食量，血液学与生化学等方面的若干特性差异较大，肿瘤发生率与死亡差别不大。     

Hwa-byung. A community study of Korean Americans.

One hundred nine Korean American community subjects were interviewed regarding their experiences with hwa-byung (HB), a Korean folk illness label commonly used by Koreans with a myriad of physiological and psychological complaints. During these interviews, standard instruments were also used to assess their depressive and somatic symptoms. The results indicated that a relatively high proportion (12%) of the subjects labeled themselves as having suffered from HB. While no apparent sociodemographic differences were found between HB and non-HB subjects, significantly more HB subjects fulfilled the diagnosis of DSM-III major depression and also had previous diagnoses of depression. The HB subjects also had significantly higher scores for the total, depressive, and somatic subscales and 16 of the 20 individual items of the Center for Epidemiologic Studies-Depression Scale. These data confirm previous observations of substantial overlap between HB and DSM-III major depression among Koreans and Korean Americans, and suggest that HB may be a culturally patterned way of expression for Koreans experiencing major depression and related conditions. The clinical and theoretical implications of these findings are also discussed.     

不同时辰刺激大鼠的交叉上核对血浆中皮质酮含量的影响

应用拉丁方设计，在不同体重组的大鼠，于不同时辰，对交叉上核采取不同强度的刺激，用放射免疫法测定外周血中皮质酮的含量。其结果显示：各体重组间无显著性差异，不同时辰血浆皮质酮的平均含量各组呈现基本相同的节律性变化，无论何时辰刺激交叉上核使之兴奋，均可显著提高血浆皮质酮的含量。完全损毁交叉上核后７２小时血浆皮质酮含量和正常对照组无显著性差异，且其节律性也没有出现明显变化。     

我国胆石病的治疗策略——排、溶、碎、取并举

胆石病在我国的发病率日渐增多。据我国多省市普查结果,该病发病率在2.4～16.8%之间。按中年以上5亿人口5%计算,专家们认为在我国至少有2500万胆石病患者,较美国人中有2000万人患胆石病,而每年约有100万新患者及50万人施行胆囊切除术为多。胆石病在我国的治疗,不同时期有着不同特点。50年代以前,基本上是属于外科治疗范围;60年代随着中西医结合的开展,非手术疗法的应用日益广泛,排石疗法日益成熟;70年代随着新溶石剂的发现,溶石疗法形成高潮;80年代西德慕尼黑大学医学院发明体外冲击波碎石术(ESWL)治疗胆囊结石,我国迅速开展;90年代我国从大的综合性医院至卫生院,均可     

Morphology of griseofulvin-resistant isolates of Mongolian variant of Trichophyton schoenleini.

Clinical, experimental and electronmicroscopic observations, and computer-enhanced images were made on 5 patients with tinea favosa resistant to griseofulvin. The pathologic fungus was identified as the Mongolian variant of Trichophyton schoenleini. The results of physical examinations, routine tests of blood, urine and stool, liver and immunologic function examinations were normal in all of the 5 patients. Under scanning electron microscopy, the surface of the spore showed pineapple-like form, the cluster of the acrogenous spores presented flower shape, and the antler-like hyphae appeared twisted in the culture. They were observed by transmission electron microscope and the images were processed by microcomputer. It was found that the cell walls of the fungi consisted of 8 layers, among which the inner layer was loose and contained cytoplasm. It was also found that all structures within the cytoplasm possessed a 1-3 layer intact envelope and there was chromatin in the nucleus. These may be contributing factors in the development of resistance to griseofulvin. This multiple-layered thick cell wall may act as a barrier responsible for the impermeability of the cell of fungi to griseofulvin.