全文获取类型
收费全文 | 219865篇 |
免费 | 20279篇 |
国内免费 | 15469篇 |
专业分类
耳鼻咽喉 | 1902篇 |
儿科学 | 2191篇 |
妇产科学 | 2979篇 |
基础医学 | 26560篇 |
口腔科学 | 3684篇 |
临床医学 | 30819篇 |
内科学 | 32938篇 |
皮肤病学 | 2226篇 |
神经病学 | 12393篇 |
特种医学 | 8223篇 |
外国民族医学 | 138篇 |
外科学 | 21724篇 |
综合类 | 35398篇 |
现状与发展 | 55篇 |
一般理论 | 19篇 |
预防医学 | 13152篇 |
眼科学 | 6698篇 |
药学 | 22721篇 |
194篇 | |
中国医学 | 12348篇 |
肿瘤学 | 19251篇 |
出版年
2024年 | 698篇 |
2023年 | 3558篇 |
2022年 | 9198篇 |
2021年 | 11561篇 |
2020年 | 8596篇 |
2019年 | 7548篇 |
2018年 | 8034篇 |
2017年 | 7085篇 |
2016年 | 6655篇 |
2015年 | 10251篇 |
2014年 | 12549篇 |
2013年 | 10692篇 |
2012年 | 16004篇 |
2011年 | 17948篇 |
2010年 | 10514篇 |
2009年 | 8182篇 |
2008年 | 11113篇 |
2007年 | 11087篇 |
2006年 | 11227篇 |
2005年 | 11322篇 |
2004年 | 6999篇 |
2003年 | 6612篇 |
2002年 | 5498篇 |
2001年 | 4935篇 |
2000年 | 5344篇 |
1999年 | 5686篇 |
1998年 | 3524篇 |
1997年 | 3497篇 |
1996年 | 2813篇 |
1995年 | 2606篇 |
1994年 | 2142篇 |
1993年 | 1376篇 |
1992年 | 1891篇 |
1991年 | 1595篇 |
1990年 | 1290篇 |
1989年 | 1091篇 |
1988年 | 1014篇 |
1987年 | 890篇 |
1986年 | 726篇 |
1985年 | 525篇 |
1984年 | 336篇 |
1983年 | 242篇 |
1982年 | 149篇 |
1981年 | 145篇 |
1980年 | 111篇 |
1979年 | 142篇 |
1978年 | 49篇 |
1977年 | 53篇 |
1975年 | 57篇 |
1974年 | 56篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
131.
石刻雕塑作业劳动卫生学调查及实验研究 总被引:1,自引:0,他引:1
测定了石雕作业粉尘浓度,几何平均浓度为82.35~3.67mg/m3。工人职业性健康检查结果,接尘工人的咽部充血、咳嗽、咯痰检出率高于对照组;肺功能低下的检出率也高于对照组。该厂自1972年以来发生尘肺患者17例,其病情发展和晋期缓慢,发病工龄长。动物实验研究表明,石雕粉尘有轻微的致纤维化作用。 相似文献
132.
133.
D B White C A Walawander D Y Liu T H Grasela 《Journal of pharmacokinetics and biopharmaceutics》1992,20(3):295-313
In a simulation study of inference on population pharmacokinetic parameters, two methods of performing tests of hypotheses comparing two populations using NONMEM were evaluated. These two methods are the test based upon 95% confidence intervals and the likelihood ratio test. Data were simulated according to a monoexponential model and, in that context, power curves for each test were generated for (i) the ratio of mean clearance and (ii) the ratio of the population standard deviations of clearance. To generate the power curves, a range of these parameters was employed; other pharmacokinetic parameters were selected to reflect the variability typically present in a Phase II clinical trial. For tests comparing the means, the confidence interval tests had approximately the same power as the likelihood ratio tests and were consistently more faithful to the nominal level of significance. For comparison of the standard deviations, and when the volume of information available was relatively small, however, the likelihood ratio test was more able to detect differences between the two groups. These results were then compared to results on parameter estimation in order to gain insight into the question of power. As an example, the nonnormality of estimates of the ratio of standard deviations plays an important role in explaining the low power for the confidence interval tests. We conclude that, except for the situation of modeling standard deviations with only sparse information, NONMEM produces tests of significance that are effective at detecting clinically significant differences between two populations. 相似文献
134.
135.
136.
Brenda M Sandmaier Storb Rainer Yanfang Liu Erlinda B Santos Eileen Bryant Friedrich G Schuening H Joachim Deeg Kristy Seidel Theodore Graham 《Transplant immunology》1996,4(4):271-274
920 cGy total body irradiation (TBI) is adequate for consistently successful engraftment of marrow from dog leukocyte antigen (DLA)-identical littermates; however, the dose is inadequate to ensure a marrow graft from DLA-nonidentical unrelated donors. Such mismatched grafts are successful only after 1800 cGy, given in three fractions. While anti-T-cell reagents enhance engraftment of DLA-identical littermate marrow after 920 cGy, they fail to be effective in the DLA-nonidentical setting. However, a monoclonal antibody (mAb) to CD44, S5, was found to be very effective in enhancing engraftment of DLA-nonidentical marrow. The current study asked whether mAb S5 was also effective in the setting of DLA-identical littermate transplants. To this purpose, the TBI dose was lowered to 450 cGy, a dose after which 70% of such grafts failed. Four dogs were treated with antibody S5, 0.2 mg/kg on days −7 though −2 (per previously published protocol), given 450 cGy TBI followed by marrow grafts from their DLA-identical littermates. All four dogs rejected their grafts; two of these died from marrow aplasia, and two survived with endogenous marrow recovery. This result was not statistically significantly different from that in 17, historical (n = 5) and concurrent (n = 12), control dogs where 11 of 17 animals rejected. Even if ten experimental animals were transplanted and all six remaining dogs engrafted, the results still would not have been significantly different from control. This result is in contrast to the successful engraftment promoted by pretreatment with antibody S5 of DLA-nonidentical unrelated dogs, consistent with the notion that different host cells are involved in graft rejection in the two disparate histocompatibility settings. 相似文献
137.
Effects of smoking and drinking on excretion of hippuric acid among toluene-exposed workers 总被引:1,自引:1,他引:0
Osamu Inoue Kazunori Seiji Takao Watanabe Haruo Nakatsuka Chui Jin Shi-Jie Liu Masayuki Ikeda 《International archives of occupational and environmental health》1993,64(6):425-430
Summary In order to investigate possible effects of smoking and drinking on the metabolism of toluence in occupational settings, 206 toluene-exposed men (mean age: 31.4 years) in shoemaking, painting, or surface-coating workshops together with 246 nonexposed control men (36.8 years) were studied for the time-weighted average intensities of exposure to toluene, hippuric acid concentration in shift-end urine samples, and the two social habits of smoking and drinking. The mean daily consumptions of cigarettes and ethanol were about 20 pieces and 10 g among smokers and drinkers, respectively. The geometric mean toluene concentration among the exposed subjects was about 20 ppm, with a maximum of 521 ppm. Regression analysis after classification of the subjects by smoking and drinking clearly demonstrated that the two social habits, when combined, markedly reduce the hippuric acid level in the urine of workers exposed to was a significant association between smoking and drinking habits, which hindered separate evaluation of the effects of the two habits on toluene metabolism. Comparison of the present results with the findings reported in the literature, however, suggested that the observed effects may be attributable to smoking rather than to drinking habits. 相似文献
138.
139.
本文报道三例肾脂肪肉瘤,并结合文献复习,讨论了其病理,临床表现、影像学特征、诊断和治疗。 相似文献
140.
糖对椰酵假单胞菌产毒性能的影响研究 总被引:3,自引:0,他引:3
以半固体LA和营养琼脂为基础培养基,分别加入葡萄糖、蔗糖、可溶性淀粉、甘油等4种成分,研究糖分对椰酵假单胞菌产毒性能影响。结果表明,椰酵假单胞菌在营养琼脂和LA半固体基础培养基上基本不产毒或产毒量很低,而葡萄糖和甘油的加入使椰酵假单胞菌的产毒能力大幅度提高,产毒量不低于在马铃薯葡萄糖琼脂(PDA)中,提示了糖代谢在椰酵假单胞菌生长和产毒过程中的重要作用。建议将LDA(含葡萄糖的LA,新设计)半固体做为一种新的椰酵假单胞菌产毒培养基,有利于实验室研究及不同实验室间的质量控制 相似文献