全文获取类型
收费全文 | 679篇 |
免费 | 23篇 |
国内免费 | 4篇 |
专业分类
耳鼻咽喉 | 3篇 |
儿科学 | 41篇 |
妇产科学 | 11篇 |
基础医学 | 65篇 |
口腔科学 | 16篇 |
临床医学 | 43篇 |
内科学 | 118篇 |
皮肤病学 | 6篇 |
神经病学 | 43篇 |
特种医学 | 38篇 |
外科学 | 92篇 |
综合类 | 12篇 |
预防医学 | 22篇 |
眼科学 | 13篇 |
药学 | 69篇 |
1篇 | |
中国医学 | 13篇 |
肿瘤学 | 100篇 |
出版年
2024年 | 1篇 |
2023年 | 5篇 |
2022年 | 11篇 |
2021年 | 15篇 |
2020年 | 10篇 |
2019年 | 12篇 |
2018年 | 23篇 |
2017年 | 10篇 |
2016年 | 10篇 |
2015年 | 12篇 |
2014年 | 31篇 |
2013年 | 33篇 |
2012年 | 50篇 |
2011年 | 55篇 |
2010年 | 30篇 |
2009年 | 25篇 |
2008年 | 30篇 |
2007年 | 29篇 |
2006年 | 35篇 |
2005年 | 30篇 |
2004年 | 37篇 |
2003年 | 24篇 |
2002年 | 19篇 |
2001年 | 15篇 |
2000年 | 13篇 |
1999年 | 10篇 |
1998年 | 6篇 |
1997年 | 4篇 |
1996年 | 4篇 |
1995年 | 9篇 |
1994年 | 1篇 |
1993年 | 1篇 |
1992年 | 19篇 |
1991年 | 17篇 |
1990年 | 18篇 |
1989年 | 10篇 |
1988年 | 9篇 |
1987年 | 9篇 |
1986年 | 10篇 |
1985年 | 3篇 |
1984年 | 2篇 |
1981年 | 2篇 |
1979年 | 1篇 |
1977年 | 1篇 |
1974年 | 1篇 |
1972年 | 1篇 |
1971年 | 2篇 |
1970年 | 1篇 |
排序方式: 共有706条查询结果,搜索用时 15 毫秒
91.
Attitudes towards suicide among medical students: comparison between Madras (India) and Vienna (Austria) 总被引:1,自引:0,他引:1
E. Etzersdorfer L. Vijayakumar W. Schöny A. Grausgruber G. Sonneck 《Social psychiatry and psychiatric epidemiology》1998,33(3):104-110
Attitudes towards suicide among medical students in Madras (India) and Vienna (Austria) were compared using the SUIATT questionnaire
by Diekstra and Kerkhof (1989). Results show a very restrictive attitude in Madras, rejecting the right to commit suicide,
nearly always judging suicide as a cowardly act, and rejecting the idea of assisted suicide. On the other hand, in Vienna
a more permissive attitude was found. It is interpreted that the Indian pattern comes close to a “medical” or “disease model”,
with stronger emphasis on mental illness, impulsiveness and emotional aspects, whereas the Viennese pattern reflects a “theoretical”,
“rational model”, concentrating on cognitive factors and minimizing the influence of mental illness, emotional difficulties
and restrictions related to suicidal behaviour. This pattern may be influenced by the public discussion on assisted suicide
and the right to die in Europe in the last decade. Possible relations to the risk for actual suicidal behaviour are discussed
using respective answers concerning previous suicidal ideation and suicide attempts. The answers concerning suicidal ideation
seem to be strongly influenced by the different attitude patterns: only 16.8% reported previous suicidal ideation in Madras,
compared to 51.5% in Vienna, whereas the percentage of reported suicide attempts is equal in both centres (5.9%:4.9%).
Accepted: 27 April 1997 相似文献
92.
Circulating immune complexes as an immunological marker in premalignant and malignant lesions of the oral cavity 总被引:1,自引:0,他引:1
P Remani R Ankathil K K Vijayan V M Haseena Beevi R Rajendran T Vijayakumar 《Cancer letters》1988,40(2):185-191
Circulating immune complexes and their immunoglobulin contents were estimated in the sera of 50 patients with oral leukoplakia, 50 patients with oral submucous fibrosis and 50 oral cancer patients. The values were compared with that of 50 normal controls. The circulating immune complexes and their immunoglobulin contents were found to be elevated significantly both in oral submucous fibrosis and oral cancer. This study seems to be of help in monitoring the malignant transformation of oral submucous fibrosis to oral cancer. 相似文献
93.
T C Ng S Grundfest S Vijayakumar N J Baldwin A W Majors I Karalis T F Meaney K H Shin F J Thomas R Tubbs 《Magnetic resonance in medicine》1989,10(1):125-134
In situ phosphorous MRS was employed to study the metabolites of normal and cancerous breasts, and the alterations of tumor response to therapy. In a group of 7 normal volunteers and 12 patients, the total mobile phosphate content of breast carcinomas was found to be at least two to three times higher than that of the normal breast measured off menstruation. The metabolite profiles of normal and tumorous breasts are coarsely similar. In both cases the intracellular pH (pHi) was either neutral or slightly alkaline (pH greater than 7.0). Prior to treatments, the metabolite levels of phosphoryl monoester-to-ATP ratio of breast neoplasms were higher than those of the controls and decreased after the patients received a few treatments while the pHi fluctuated at a value greater than 7.0. The phosphoryl diester-to-ATP ratio also demonstrated to a lesser extent a decreasing trend in response to therapy. 相似文献
94.
95.
Mota HC; Vijayakumar S; Sibata C; Higgins PD; Thomas FJ; Saxton J; Weinstein M 《Radiology》1988,168(3):859-861
To determine the optimal width of a midline posterior spinal block (MPSB) (to avoid delivering too great a dose to the cord and too small a dose to adjacent tissue), the authors determined with magnetic resonance (MR) imaging normal ranges of cord depth and width and correlated them with film dosimetric data. In 59 randomly selected patients there was a wide range for both depth and width. The average depths of the anterior and posterior surfaces of the cord were 6.7 cm +/- 1.4 and 5.4 cm +/- 1.3, respectively. The average cord width was 1.6 cm +/- 0.4. Optimal cord block width as a function of cord width was determined for a 6-MV photon beam. The optimal cord block width at the surface (half-value layer [HVL] thickness = 6) varied from 1.5 to 3.0 cm for cord widths of 0.8-2.4 cm, which correspond to two standard deviations from the average. There was no significant dependence on depth of the cord. For optimal treatment outcome, the MPSB width may have to be determined for each patient individually. 相似文献
96.
Metastases to the pineal gland is an uncommon event. Bronchogenic carcinomas are the most frequent source of the primary lesion. A case of small cell carcinoma of the lung with solitary metastases to the pineal gland is reported; the literature is reviewed. 相似文献
97.
PURPOSE: To study the effect of piperine, an alkaloid, on thyroid hormones and apolipoproteins in high-fat-diet (HFD) and antithyroid drug-induced hyperlipidemic rats. EXPERIMENTAL: Male Wistar rats were first divided into two groups, control diet and high-fat diet (HFD) and then subdivided into four subgroups of ten animals each. The animals were treated with the following regimens for 10 weeks: 1% carboxymethyl cellulose; 10 mg carbimazole (CM)/kg body weight; 10 mg CM + 40 mg piperine/kg body weight, and 10 mg CM + 2 mg atorvastatin /ATV//kg body weight. Lipid profiles, hormone levels, and apolipoprotein levels were studied in all groups. RESULTS: HFD and/or CM administration significantly elevated the plasma levels of total cholesterol, VLDL, LDL, triglycerides, free fatty acids, and phospholipids, but significantly reduced the HDL levels. Moreover, CM administration significantly reduced apo A-I levels and T3, T4 and testosterone levels while significantly elevating plasma apo B, thyroid stimulating hormone (TSH) and insulin levels. The simultaneous administration of piperine and HFD significantly reduced plasma lipids and lipoproteins levels, except for HDL, which was significantly elevated. Piperine supplementation also improved the plasma levels of apo A-I, T3, T4, testosterone, and I and significantly reduced apo B, TSH, and insulin to near normal levels. CONCLUSIONS: The data presented here provide evidence that piperine possesses thyrogenic activity, thus modulating apolipoprotein levels and insulin resistance in HFD-fed rats, opening a new view in the management of dyslipidemia by dietary supplementation with nutrients. 相似文献
98.
Narasimhan S Govindarajan R Madhavan V Thakur M Dixit VK Mehrotra S Madhusudanan KP 《Planta medica》2006,72(15):1421-1424
A fructo-oligosaccharide was isolated from Chlorophytum borivilianum and identified as O-beta-D-fructofuranosyl-(2-->1)-(beta-D-fructofuranosyl) (n)-(2-->1)-alpha-D-glucopyranoside (n = 5 - 30) using high-pressure anion exchange chromatography, MALDI-MS, NMR, GC, HPTLC and chemical analysis. The extract and the fructo-oligosaccharide were found to have significant antidiabetic activity with the blood sugar levels being 118.32 +/- 3.56 and 110.21 +/- 4.22, respectively, as compared to the control value of 231.25 +/- 3.03 along with moderate antioxidant activity in streptozotocin-induced diabetic animals. 相似文献
99.
Lohith K Vijayakumar GR Somashekar BR Sivakumar R Divakar S 《European journal of medicinal chemistry》2006,41(9):1059-1072
About 12 glycosides prepared through amyloglucosidase catalysis and 23 amino acyl esters of carbohydrates prepared through lipase catalysis in organic solvents showed angiotensin converting enzyme (ACE) inhibition activity. Both amino acyl esters of carbohydrates and glycosides exhibited IC50 values for ACE inhibition in the 0.5 mM to 15.7 mM range. Eugenyl-D-glucoside (IC50: 0.5+/-0.04 mM), L-isoleucyl-D-glucose (IC50: 0.7+/-0.067 mM), vanillyl-D-sorbitol (IC50: 0.8+/-0.09 mM), L-histidyl-D-fructose (IC50: 0.9+/-0.087 mM), L-tryptophanyl-D-fructose (IC50: 0.9+/-0.092 mM), octyl-D-glucoside (IC50: 1.0+/-0.093 mM), vanillyl-D-mannoside (IC50: 1.0+/-0.089 mM), L-valyl-D-mannitol (IC50: 1.0+/-0.092 mM) and L-phenylalanyl-D-glucose (IC50: 1.0+/-0.089 mM) were the compounds, which showed the best ACE inhibitory activities. 相似文献
100.
Total rosette forming cells (TRFC) and high affinity rosette forming cells (HARFC) were enumerated in 534 patients with carcinoma of oral cavity, uterine cervix or breast, and the results were compared with adult controls. The HARFC levels were found to be significantly decreased in cancer patients, and this decrease was more pronounced in advanced clinical stages. The HARFC levels returned to normal in patients who had a clinical cure but remained low in patients having residual disease. Enumeration of HARFC may therefore be useful in assessing the cell mediated immunity in cancer patients. 相似文献