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81.
82.
Salari Nader Kazeminia Mohsen Shohaimi Shamarina Mohammadi Masoud 《Clinical rheumatology》2021,40(11):4511-4525
Clinical Rheumatology - Rheumatoid arthritis is a chronic inflammatory and systemic autoimmune disease associated with synovial fluid inflammatory lesions and articular changes. The aim of the... 相似文献
83.
Mohamed Tarek M. Youssef Menna Allah M. Bakry Azza A. El-Keiy Mai M. 《Metabolic brain disease》2021,36(2):255-264
Metabolic Brain Disease - The foremost neurodegenerative disease is Alzheimer’s (AD), which is characterized as a gradual decrease in memory, cognitive function, and also personal changes... 相似文献
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The hepatitis C virus (HCV) is a common blood-borne illness that affects up to 2% of the world’s population and almost 4 million
Americans. Cognitive impairment, or difficulty with thinking, has become a well-established symptom in persons with end stage
liver disease. It was previously assumed that cognitive impairment was a consequence of cirrhosis-associated hepatic encephalopathy.
Recent evidence, however, suggests that approximately one-third of people with chronic HCV experience cognitive impairment
even in the absence of cirrhosis and that its occurrence is unrelated to other indices of liver function, such as laboratory
values, viral load, and genotype. In the present review, evidence outlining the presence of cognitive deficits associated
with HCV, possible etiological factors, effects of antiviral therapy, and co-infection with human immunodeficiency virus (HIV)
is presented. Implications of these findings and directions for future work are discussed. 相似文献
86.
Abdel Aziz TA Kumar P Bazargani N Al-Hato E Al Khaja N 《Asian cardiovascular & thoracic annals》2003,11(2):102-106
Twenty-one patients undergoing coronary artery bypass grafting were prospectively evaluated by conventional selective coronary angiography and electron-beam computed tomography. Eighty bypass grafts (60 saphenous vein and 20 left or right internal mammary artery) were evaluated for patency. The sensitivity and specificity of electron-beam computed tomography were 72% and 100%, respectively; positive and negative predictive values were 100% and 92.5%, respectively. Sensitivity and specificity according to coronary region were: left anterior descending artery, 33% and 100%; diagonal artery, 67% and 100%; circumflex artery, 75% and 100%; right coronary artery, 100% and 100%. Electron-beam computed tomography is relatively accurate and a promising tool for noninvasive evaluation of graft patency after coronary artery bypass graft surgery. 相似文献
87.
Mahmoud NOUR Khatim MUSTAFA Khadadah MOUSA Adnan ABUL Hani SHUHAIBAR Abdul Mohsen Mohsen 《Respirology (Carlton, Vic.)》1998,3(1):25-31
Lung function was studied in 24 patients with advanced mitral stenosis scheduled for mitral valve replacement (MVR), and revealed an obstructive ventilatory pattern [rewording of this sentence OK] . Forty per cent of the patients had a forced expiratory volume in 1 s (FEV1)<60% of that predicted in the preoperative period. Twenty-five per cent of those operated upon showed a similar pattern up to 110 weeks postoperatively. A blind study of the effect of placebo and β2 agonist (salbutamol) inhalation was performed preoperatively and 6 months postoperatively, to evaluate the reversibility of airflow obstruction in these patients, flow volume curve and body plethysmographic measurement of airway resistance (Rex) and intrathoracic gas volume (VTG). Patients in the pre and postoperative period showed a significant difference between the placebo and the β2 agonist responses for FEV1, FEV1 as percentage of FVC (FEV1% FVC), peak expiratory flow rate (PEFR), flow rate of 50% of expiratory vital capacity ([¨max50), Rex and VTG (P<0.001). We conclude that salbutamol inhalation improves obstructive impairment in patients with MVR pre- and postoperatively. 相似文献
88.
Alexander J Javois Tarek S Husayni David Thoele Andrew H Van Bergen 《Catheterization and cardiovascular interventions》2006,67(3):485-489
We report a 12-month old patient who presented for murmur evaluation after percutaneous closure of type C patent ductus arteriosus (PDA) using a 10 mm Amplatzer Vascular Plug (AGA Medical Corporation, Golden Valley, MN) at an outside institution. Echocardiography revealed a large left-to-right shunt through the implanted device, inadvertently stenting the PDA instead of closing it. The patient underwent repeat catheterization with successful coil implantation within the Amplatzer Vascular Plug, completely eliminating the large residual ductal shunt. Although challenging, this case illustrates the technique of implanting coils within this occlusion device. This case also illustrates that occlusion of type C PDA utilizing the Amplatzer Vascular Plug may not only result in incomplete occlusion but also create a potentially worse clinical situation in which the PDA is stretched larger and stented open. Without consideration of simultaneous coil implantation within this device, use of the Amplatzer Vascular Plug might be contraindicated in type C PDA, because there may be no way to ensure successful closure by the Vascular Plug alone. 相似文献
89.
M Mohsen Ibrahim 《Current hypertension reports》2018,20(5):38
Purpose of Review
Outline recent epidemiologic data regarding hypertension in developing countries, distinguish differences from developed countries, and identify challenges in management and future perspectives.Recent Findings
Increased sugar intake, air and noise pollution, and low birth weight are emerging hypertension risk factors. The major challenges in management are difficulties in accurate diagnosis of hypertension and adequate blood pressure control.Summary
In contrast to developed countries, hypertension prevalence rates are on the rise in developing countries with no improvement in awareness or control rates. The increasing burden of hypertension is largely attributable to behavioral factors, urbanization, unhealthy diet, obesity, social stress, and inactivity. Health authorities, medical societies, and drug industry can collaborate to improve hypertension control through education programs, public awareness campaigns, legislation to limit salt intake, encourage generic drugs, development and dissemination of national guidelines, and involving nurses and pharmacists in hypertension management. More epidemiologic data are needed in the future to identify reasons behind increased prevalence and poor blood pressure control and examine trends in prevalence, awareness, treatment, and control. National programs for better hypertension control based on local culture, economic characteristics, and available resources in the population are needed. The role of new tools for hypertension management should be tested in developing world.90.
Israa A. Seliem Siva S. Panda Adel S. Girgis Yosra I. Nagy Riham F. George Walid Fayad Nehmedo G. Fawzy Tarek S. Ibrahim Amany M. M. Al‐Mahmoudy Rajeev Sakhuja Zakaria K. M. Abdel‐samii 《Chemical biology & drug design》2020,95(2):248-259
A series of new fluoroquinolone conjugates 8a–g and 9a–f were synthesized via benzotriazole‐mediated synthetic approach with good yield and purity. Some of the synthesized analogs exhibited significant antibacterial properties against Escherichia coli and Staphylococcus aureus with potency higher than that of the parent drugs through in vitro standard bioassay procedure (conjugates 8c and 8d reveal antimicrobial properties with potency 1.9, 61.9, 20.7 and 2.4, 37.1, 8.3 folds relative to the parent antibiotic 6 against E. coli, S. aureus, and Enterococcus faecalis, respectively). The observed experimental data were supported by enzymatic DNA gyrase inhibitory property. Developed BMLR‐QSAR model validates the observed experimental data and recognizes the parameters responsible for the enhanced antibacterial properties. 相似文献