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121.
I. P. Smirnova S. B. Alekseev S. V. Diorditsa V. S. Vesa I. Z. Zaitsev 《Bulletin of experimental biology and medicine》1999,128(6):1226-1228
Positive effect of local treatment with L-lysine-a-oxidase on the course of herpes genital infection was demonstrated on guinea
pigs even after the appearance of infection symptoms. In animals treated with L-lysine-a-oxidase, the severity of the disease,
virus reproduction and virus-induced changes in cells were significantly less pronounced than in untreated animals. The preparations
exerted no toxic effects.
Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 128, No. 12, pp. 654–656, December, 1999. 相似文献
122.
I. N. Tyurenkov V. N. Perfilova L. A. Smirnova A. F. Ryabukha E. A. Suchkov S. A. Lebedeva 《Pharmaceutical Chemistry Journal》2011,44(12):702-704
An ion-pair chromatography method is developed using a reversed-phase C18 column with UV detection for the quantitative analysis
of phenibut. The proposed method possesses sufficient selectivity and high sensitivity that enable its effective use during
pharmacokinetic studies of phenibut in addition to other GABA derivatives in biological samples. 相似文献
123.
124.
A study was made of the causes and factors that determine disability in 102 able-bodied patients suffering from essential hypertension (a random sample), who were acknowledged invalids for the first time in 1989. Analysis of the shortcomings in the organization of the treatment and prophylactic aid to the population made it possible to outline the main trends in disability prevention in patients suffering from essential hypertension. 相似文献
125.
Smirnova A. P. Krasnoshchekova S. P. Nikitina A. M. Shvachkin Yu. P. 《Pharmaceutical Chemistry Journal》2002,36(8):443-444
Pharmaceutical Chemistry Journal - 相似文献
126.
Boris Lebedev Natal'ya Smirnova Nina Novosyolova Kiryll Makovetskii Irina Ostrovskaya 《Macromolecular chemistry and physics.》1994,195(5):1807-1822
Thermodynamic properties of 5-trimethylsilyl-2-norbornene (TMSNB) and poly(5-trimethyl-silyl-2-norbornene) (PTMSNB), viz. the temperature dependence of the isobaric heat capacity Cop of the monomer between 10 and 330 K and of the polymer from 7 to 600 K, were studied by adiabatic vacuum and differential dynamic calorimetry. Temperature and enthalpy of monomer melting as well as parameters of glass transition and glassy state of the monomer and the polymer were determined. From the experimental data, the thermodynamic functions H°(T)-H°(0), S°(T) and G°(T)-H°(0) were calculated for TMSNB in the range of 0 to 330 K and for PTMSNB from 0 to 380 K. In a differential automatic calorimeter, the enthalpy of polymerization of TMSNB to PTMSNB in toluene solution was measured at T = 301 K and p = 101,325 kPa. Under similar physical conditions and in the same calorimeter, enthalpies of dissolution for the monomer and the polymer were estimated. The results were used to calculate the enthalpy, entropy and Gibbs function of bulk polymerization of TMSNB in the range of 0 to 380 K at standard pressure. The ceiling temperature of the polymerization process was also evaluated. 相似文献
127.
Atko Viru Livian Laaneots Kalle Karelson Tamara Smirnova Mehis Viru 《European journal of applied physiology》1998,77(5):401-408
The dependence of exercise-induced hormone responses on sexual maturation was tested in a 3-year longitudinal experiment on 34 girls (aged 11–12 years at the beginning). Sexual maturation was evaluated by Tanners five-stage scale. Children cycled for 20-min at 60% maximal oxygen uptake once a year. Cortisol, insulin, growth hormone, β-oestradiol, progesterone and testosterone concentrations in venous blood were determined by radioimmunoassay procedures. Basal concentrations of growth hormone increased and of cortisol decreased when breast stage III was reached. Reaching breast stage IV was associated with an increase in basal concentrations of β-oestradiol, progesterone and testosterone. The exercise induced significant increases in concentrations of cortisol, growth hormone and β-oestradiol and a decrease in insulin concentration. At breast stage III the increase in cortisol concentration was to a lower level [467 (SEM 42) vs 567 (SEM 46)nmol · l?1] and growth hormone concentration to a higher level [29.4 (SEM 0.5) vs 12.8 (SEM 0.4)ng · ml?1], while the fall in insulin concentration was less pronounced [postexercise level 10.6 (SEM 0.9) vs 7.8 (SEM 0.8)mU · l?1] than in stage II. The magnitude of the cortisol response was reduced in the last stage of breast development (+42.1% vs +55.5% at stage II, +66.2% at stage III, and +50.0% at stage IV). The magnitude of β-oestradiol response was the lowest in breast stage IV (+15.8%) and the highest at stage V (+41.1%). The progesterone response became significant at stage IV and testosterone response at stage V. In conclusion, we found that reaching breast stage III was associated with altered responses of cortisol, insulin and growth hormone concentrations while the responses of the sex hormone concentrations became pronounced in the last stages of sexual maturation. 相似文献
128.
JH Raphael JL Southall TV Gnanadurai GJ Treharne GD Kitas 《BMC musculoskeletal disorders》2002,3(1):17-8
Background
Continuous intrathecal drug delivery has been shown in open studies to improve pain and quality of life in those with intractable back pain who have had spinal surgery. There is limited data on long term effects and and even less for patients with mechanical back pain without prior spinal surgery. 相似文献129.
I. D. Bystryakova O. A. Burova G. M. Chelysheva S. V. Zhilinkova N. M. Smirnova T. S. Safonova 《Pharmaceutical Chemistry Journal》1991,25(12):874-876
Translated from Khimiko-farmatsevticheskii Zhurnal, Vol. 25, No. 12, pp. 31–33, December, 1991. 相似文献
130.
A P Chudina L A Savluchinskaia A V Mikha?lovski? N A Smirnova 《Vestnik dermatologii i venerologii》1990,(9):72-73
Basal-cell nevus was diagnosed in a 60-year-old patient who suffered for 20 years from multiple basal-cell carcinomas. Autopsy has revealed congenital absence of the right kidney and ureter after his death at the age of 61. 相似文献