全文获取类型
收费全文 | 3923篇 |
免费 | 277篇 |
国内免费 | 28篇 |
专业分类
耳鼻咽喉 | 47篇 |
儿科学 | 80篇 |
妇产科学 | 87篇 |
基础医学 | 511篇 |
口腔科学 | 142篇 |
临床医学 | 362篇 |
内科学 | 752篇 |
皮肤病学 | 89篇 |
神经病学 | 178篇 |
特种医学 | 89篇 |
外科学 | 365篇 |
综合类 | 169篇 |
一般理论 | 2篇 |
预防医学 | 471篇 |
眼科学 | 94篇 |
药学 | 442篇 |
中国医学 | 77篇 |
肿瘤学 | 271篇 |
出版年
2024年 | 5篇 |
2023年 | 81篇 |
2022年 | 240篇 |
2021年 | 369篇 |
2020年 | 204篇 |
2019年 | 178篇 |
2018年 | 229篇 |
2017年 | 152篇 |
2016年 | 166篇 |
2015年 | 177篇 |
2014年 | 209篇 |
2013年 | 233篇 |
2012年 | 342篇 |
2011年 | 344篇 |
2010年 | 186篇 |
2009年 | 131篇 |
2008年 | 173篇 |
2007年 | 160篇 |
2006年 | 127篇 |
2005年 | 96篇 |
2004年 | 95篇 |
2003年 | 70篇 |
2002年 | 67篇 |
2001年 | 11篇 |
2000年 | 13篇 |
1999年 | 15篇 |
1998年 | 8篇 |
1997年 | 8篇 |
1996年 | 8篇 |
1995年 | 8篇 |
1994年 | 6篇 |
1993年 | 6篇 |
1992年 | 11篇 |
1991年 | 4篇 |
1990年 | 7篇 |
1989年 | 8篇 |
1988年 | 10篇 |
1987年 | 9篇 |
1986年 | 9篇 |
1985年 | 5篇 |
1984年 | 5篇 |
1983年 | 5篇 |
1982年 | 3篇 |
1981年 | 3篇 |
1979年 | 5篇 |
1975年 | 3篇 |
1974年 | 3篇 |
1973年 | 2篇 |
1972年 | 4篇 |
1945年 | 2篇 |
排序方式: 共有4228条查询结果,搜索用时 0 毫秒
121.
Mohammed AlSheef Mastourah Alotaibi Abdul Rehman Z. Zaidi Areej Alshamrani Aroub Alhamidi Syed Ziauddin A. Zaidi Noor Alanazi Sarah Alhathlool Ohoud Alarfaj Mohammed AlHazzaa Ghaydaa Kullab Amany Alboghdadly Amani Abu-Shaheen 《Saudi medical journal》2020,41(10):1063
Objectives:To identify the epidemiologic profile of cerebral vein thrombosis (CVT) among fasting women using oral contraceptive pills (OCPs) during the holy month of Ramadan.Methods:This retrospective study was conducted on all patients diagnosed with CVT and using OCPs from records at a tertiary care hospital in Riyadh, Saudi Arabia during 2016-2017. The study participants were categorized into 2 groups (an intermittently fasting group during the holy month of Ramadan and a non-fasting group).Results:Out of 108 female patients with CVT, 36.1% were secondary to OCP, of whom 41% participants were fasting. The most affected site was the transverse sinus. Holocephalic headache was more common amongst fasting group (68.8%) compared to non-fasting group (30.4%) (p=0.025). Dehydration (p=0.003) amongst the fasting group and protein S deficiency (p=0.027) in the non-fasting group were identified as the 2 prominent risk factors. Unfractionated heparin was the most common anticoagulant therapies used during the initiation phase for non-fasting (36.4%) and fasting groups (50%).Conclusion:All women who are using OCP should undergo formal written risk assessments for factors of CVT. Our study suggests that the negative effects of OCPs use might outweigh its benefits; thus, it should be prescribed with caution, more so in fasting patients. 相似文献
122.
Roshan Mazhar Noor Azhar Shazili Faizah Shaharom Harrison 《Parasitology research》2014,113(10):3737-3743
In February 2013, forty-seven Notched threadfin bream, the Nemipterus peronii, were sampled from the eastern coastal waters of the South China Sea. The concentration of various elements, namely cadmium (Cd), chromium (Cr), copper (Cu), mercury (Hg), strontium (Sr), manganese (Mn), selenium (Se), Lead (Pb), nickel (Ni), aluminum (Al), arsenic (As), iron (Fe), and Zinc (Zn) were analyzed in the liver, muscle, and kidney organs of the host, as well as in their parasites Hysterothalycium reliquens (nematode) and the Paraphilometroides nemipteri (nematode), using inductively coupled plasma mass spectrometry (ICP-MS). The former group of parasites showed highest accumulation capacity for Cr, Cu, Fe, Mn, Se, Ni, and Zn while the latter group had high accumulation potential of As, Hg, Cd, Al, Pb, and Sr. The divergence in heavy-metal accumulation profiles of both nematodes is linked with the specificity of microhabitats, cuticle morphology, and interspecific competition. The outcome of this study indicates that both parasite models can be used for biomonitoring of metal pollution in marine ecosystems. 相似文献
123.
Azizullah Azizullah Zia Ur Rehman Imran Ali Waheed Murad Noor Muhammad Waheed Ullah Donat-Peter Häder 《Parasitology research》2014,113(12):4321-4326
Dengue, a mosquito-borne viral infection, is one of the major public health concerns in the tropical and subtropical regions of the world. Approximately, 2.5 billion people across the world are at risk from dengue and 50 to 100 million new infections of dengue occur annually. There is yet no vaccine or medicine available against dengue, and treatment remains only supportive. Targeting its vector by a combination of biological and chemical approaches and management of breeding sites are currently the only existing approaches to control or eliminate dengue. Chlorophyll derivatives like chlorophyllin and pheophorbide have been reported as effective natural photosensitizers against larvae of several insects including flies. Chlorophyll derivatives were also reported effective against larval stages of freshwater snails as well as against certain parasites of fish. This article briefly discusses the possible application of chlorophyll derivatives in controlling dengue vectors and hence the disease itself. Chlorophyll derivatives can prove to be a good contributor in an integrated approach against dengue. 相似文献
124.
Badriya Al-Rahbi Rahimah Zakaria Zahiruddin Othman Asma Hassan Zul Izhar Mohd Ismail Sangu Muthuraju 《Acta histochemica》2014
Recently, our research team has reported that Tualang honey was able to improve immediate memory in postmenopausal women comparable with that of estrogen progestin therapy. Therefore the aim of the present study was to examine the effects of Tualang honey supplement on hippocampal morphology and memory performance in ovariectomized (OVX) rats exposed to social instability stress. Female Sprague-Dawley rats were divided into six groups: (i) sham-operated controls, (ii) stressed sham-operated controls, (iii) OVX rats, (iv) stressed OVX rats, (v) stressed OVX rats treated with 17β-estradiol (E2), and (vi) stressed OVX rats treated with Tualang honey. These rats were subjected to social instability stress procedure followed by novel object recognition (NOR) test. Right brain hemispheres were subjected to Nissl staining. The number and arrangement of pyramidal neurons in regions of CA1, CA2, CA3 and the dentate gyrus (DG) were recorded. Two-way ANOVA analyses showed significant interactions between stress and OVX in both STM and LTM test as well as number of Nissl-positive cells in all hippocampal regions. Both E2 and Tualang honey treatments improved both short-term and long-term memory and enhanced the neuronal proliferation of hippocampal CA2, CA3 and DG regions compared to that of untreated stressed OVX rats. 相似文献
125.
Mohd. Aamir Kundan Mittal Jaya Shankar Kaushik Haripal Kashyap Gurpreet Kaur 《Indian journal of pediatrics》2014,81(11):1167-1170
Objective
To determine the sociodemographic and clinical factors leading to stress among parents whose children are admitted in pediatric intensive care unit (PICU).Methods
A prospective observational study was conducted in PICU of a tertiary care hospital of north India. Parents of children admitted to PICU for at least 48 h duration were eligible for participation. At the end of 48 h, parental stress was assessed using parental stress scale (PSS:PICU) questionnaire which was administered to the parents. Baseline demographic and clinical parameters of children admitted to PICU were recorded. The parental stress was compared with demographic and clinical characteristics of children using appropriate statistical methods.Results
A total of 49 parents were finally eligible for participation. Mean (SD) parental stress scores was highest in domains of procedures [1.52 (0.66)] and behavior and emotional [1.32 (0.42)] subscales. Mean (SD) total parental stress score among intubated children [1.31 (0.25)] was significantly more than among non intubated children [0.97 (0.26)] (p?0.001). However, parental stress score were comparable in terms of gender (p?=?0.15) and socioeconomic status (p?=?0.32). On subscale analysis, it was found that professional communication is a significant stressor in age groups 0–12 mo [0.61(0.41)] (p?=?0.02). It was observed that parents of intubated children were significantly stressed by the physical appearance of their children (p?0.001), procedures performed on them (p?=?0.008) and impairment in parental role (p?=?0.002). Total parental stress score had a positive correlation with PRISM score (r?=?0.308).Conclusions
Indian parents are stressed maximally with environment of PICU. Factor leading to parental stress was intubation status of the child and was not affected by gender or socio demographic profile of the parents. 相似文献126.
Lamellar bending habits, as influenced by molecular‐chain chirality, in packing into dendritic spherulites with specific optical patterns are discussed using two model polymers of opposite chirality that are blended with a common polymer as examples: i) poly(l ‐lactic acid)/poly(butylene adipate) (PLLA/PBA) and ii) poly(d ‐lactic acid)/PBA (PDLA/PBA) blends. The bending habits in the spherulites of PLLA or PDLA blended with PBA are dictated by the chirality, specifically the counterclockwise and clockwise directions for the PLLA/PBA (50:50) and PDLA/PBA (50:50) blends, respectively. Straight lamellae in spiral lozenge crystals are packed with crystal aggregates of PLLA on top of the flat‐on lamellae plates acting as a basal plane during crystallization at Tc; spiral lozenge‐crystal frameworks are surrounded by needle‐like crystals resembling PBA crystals.
127.
Din Syafruddin Michael J. Bangs Dian Sidik Iqbal Elyazar Puji BS Asih Krisin Chan Siti Nurleila Christian Nixon Joko Hendarto Isra Wahid Hasanuddin Ishak Claus B?gh John P. Grieco Nicole L. Achee J. Kevin Baird 《The American journal of tropical medicine and hygiene》2014,91(6):1079-1087
A randomized, double-blinded, placebo-controlled study was conducted to examine the effect of spatial repellent (SR) in households at risk of malaria in Indonesia. Following presumptive radical cure for malaria in 180 adult men representing sentinels of new infection in four clusters within two villages, all households were given either metofluthrin or placebo mosquito coils. Weekly blood smear screening and human-landing mosquito catches were done throughout the 6 months intervention. Malaria infections occurred in 61 subjects living in placebo households and 31 subjects living in SR coil households, suggesting a 52% protective effect of SR. Likewise, anopheles indoor human landing rates were 32% lower in homes receiving SR coils. Differences in the malaria attack rate between SR- and placebo-treated homes was significant when not accounting for the effects of clustering. When the analysis was adjusted for intra-cluster correlation, the differences between SR- and placebo-treated homes were not statistically significant. The findings provide evidence of SR public health benefit and support a larger trial statistically powered to detect those effects. 相似文献
128.
Nafeeza Mohd Ismail Ibrahim Abdel Aziz Ibrahim Najihah Binti Mohd Hashim Kamsiah Jaarin 《Archives of Medical Science》2013,9(6):1132-1137
Introduction
Captopril is an angiotensin-converting enzyme inhibitor, which is used as an antihypertensive agent and has shown antioxidant properties. This study aims at determining the effects of captopril on factors affecting gastric mucosal integrity in aspirin-induced gastric lesions.Material and methods
Eighteen male Sprague-Dawley (200-250 g) rats that were given aspirin (40 mg/100 g body weight) were divided into three groups: the control, captopril (1 mg/100 g body weight daily) and ranitidine (2.5 mg/100 g body weight twice daily) groups. Ranitidine and captopril were given orally for 28 days. Rats in all groups were sacrificed and the parameters measured.Results
Captopril reduced gastric acidity, and increased gastric glutathione (GSH) and prostaglandin E2 (PGE2) significantly in comparison to the control group. Captopril also reduced malondialdehyde (MDA) and gastric lesions insignificantly compared to the control group. Ranitidine healed the lesions significantly compared to the control group. There was no difference between ranitidine and captopril on the severity of lesions, gastric acidity, MDA and GSH. Captopril increased PGE2 compared to ranitidine (p < 0.05).Conclusions
Captopril has desirable effects on the factors affecting gastric mucosal integrity (acidity, PGE2 and GSH) and is comparable to ranitidine in ulcer healing. 相似文献129.
Jamaludin Mohamed Saw Wuan Shing Muhd Hanis Md Idris Siti Balkis Budin Satirah Zainalabidin 《Clinics (S?o Paulo, Brazil)》2013,68(10):1358-1363